←Back to structures

thymidine_kinase

Euk-Vir

Papiine_alphaherpesvirus_2

thymidine_kinase__YP_443869__Papiine_alphaherpesvirus_2__340907

Identity

Accession:
YP_443869 ↗
Protein ID:
thymidine_kinase
Kingdom:
euk

Quality

84.4 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Simplexvirus› Papiine_alphaherpesvirus_2

TaxID: 340907

Cluster

View cluster (35 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 34-267
PDB
Domain cluster: rep: thymidine_kinase__YP_009230154__Leporid_alphaherpesvirus_4__481315__D1-149_256-295
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00693.25 best Herpes_TK 274.7 1.20e-81 97.0% 77.1%
CATH (10)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1e2jA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.98 86.0 7.66e-01 100.0% 68.3%
1osnC00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.91 84.0 7.47e-01 100.0% 70.6%
1p72A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.90 85.0 7.41e-01 100.0% 69.7%
1zm7B00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.80 61.0 6.61e-01 97.0% 90.9%
1p5zB00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.76 61.0 6.22e-01 86.8% 84.3%
3a4lB01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.73 44.0 5.04e-01 85.5% 78.1%
3lv8A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.72 51.0 5.46e-01 84.6% 82.8%
2plrA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.68 51.0 5.32e-01 84.6% 83.5%
2yevA03 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.58 38.0 4.22e-01 77.8% 82.1%
2zy9A03 1.10.357.20 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › SLC41 divalent cation transporters, integral membrane domain 0.51 30.0 3.40e-01 87.2% 75.3%
ECOD (18)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1322887 2004.1.1.52 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Herpes_TK 0.98 86.0 7.64e-01 100.0% 68.0%
9545 2004.1.1.52 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Herpes_TK 0.90 88.0 7.60e-01 100.0% 70.6%
9546 2004.1.1.52 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Herpes_TK 0.88 85.0 7.42e-01 100.0% 71.4%
5072526 2004.1.1.70 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › dNK 0.85 58.0 6.42e-01 85.5% 84.2%
3753842 2004.1.1.70 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › dNK 0.84 62.0 6.31e-01 85.5% 77.3%
5072252 2004.1.1.79 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin 0.81 59.0 6.37e-01 96.6% 84.9%
5034778 2004.1.1.79 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin 0.77 52.0 5.79e-01 84.2% 83.7%
4240907 2004.1.1.79 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin 0.77 54.0 5.89e-01 85.5% 84.6%
4969776 2004.1.1.79 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin 0.77 54.0 5.81e-01 84.6% 81.5%
4314340 2004.1.1.79 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin 0.76 53.0 5.71e-01 85.5% 81.0%
5043901 2004.1.1.79 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin 0.75 55.0 5.94e-01 96.6% 86.5%
4435067 2004.1.1.70 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › dNK 0.74 62.0 6.04e-01 85.9% 80.0%
3281753 2004.1.1.208 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_33 0.70 44.0 4.85e-01 84.2% 75.9%
None — 0.59 32.0 3.61e-01 94.4% 65.6%
4278244 140.1.1.5 ↗ alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon_1 0.58 32.0 3.53e-01 94.4% 62.1%
4066781 140.1.1.5 ↗ alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon_1 0.57 30.0 3.23e-01 94.4% 55.6%
3277496 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.54 44.0 4.08e-01 84.2% 77.2%
5064613 140.1.1.5 ↗ alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon_1 0.54 31.0 3.09e-01 74.8% 51.2%