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thymidylate_synthase

Euk-Vir

Common_midwife_toad_virus

thymidylate_synthase__YP_009508652__Common_midwife_toad_virus__540070

Identity

Accession:
YP_009508652 ↗
Protein ID:
thymidylate_synthase
Kingdom:
euk

Quality

91.7 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 39-95
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00303.25 best Thymidylat_synt 63.9 1.80e-17 100.0% 21.9%
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3egyX00 3.30.572.10 Alpha Beta › 2-Layer Sandwich › Thymidylate Synthase; Chain A › Thymidylate synthase/dCMP hydroxymethylase domain 0.96 85.0 5.36e-01 93.0% 22.6%
1bo7A00 3.30.572.10 Alpha Beta › 2-Layer Sandwich › Thymidylate Synthase; Chain A › Thymidylate synthase/dCMP hydroxymethylase domain 0.91 83.0 5.07e-01 100.0% 18.0%
1bkpA00 3.30.572.10 Alpha Beta › 2-Layer Sandwich › Thymidylate Synthase; Chain A › Thymidylate synthase/dCMP hydroxymethylase domain 0.87 78.0 4.90e-01 100.0% 20.5%
1tisA00 3.30.572.10 Alpha Beta › 2-Layer Sandwich › Thymidylate Synthase; Chain A › Thymidylate synthase/dCMP hydroxymethylase domain 0.73 62.0 3.99e-01 100.0% 24.1%
5awwY00 1.10.3370.10 Mainly Alpha › Orthogonal Bundle › Preprotein translocase SecY subunit › SecY subunit domain 0.55 40.0 2.53e-01 87.7% 97.4%
ECOD (9)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3479792 266.1.1.0 a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase 0.96 87.0 5.27e-01 96.5% 17.7%
4664958 266.1.1.0 a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase 0.93 87.0 5.40e-01 100.0% 21.6%
2540892 266.1.1.1 a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt 0.92 86.0 5.16e-01 100.0% 17.3%
4108234 266.1.1.1 a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt 0.91 82.0 4.94e-01 96.5% 17.2%
1900468 266.1.1.1 a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt 0.89 82.0 5.08e-01 100.0% 20.4%
4151800 266.1.1.1 a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt 0.89 82.0 5.01e-01 100.0% 18.8%
4225236 266.1.1.1 a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt 0.88 79.0 4.96e-01 100.0% 20.1%
3732819 4019.1.1.1 alpha complex topology › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › Beta-lactamase 0.52 42.0 2.61e-01 94.7% 98.3%
3416836 7516.1.1.112 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Fringe, CHGN 0.50 39.0 2.61e-01 91.2% 84.0%