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topoisomerase_2
Euk-VirOstreococcus_lucimarinus_virus_OlV5
topoisomerase_2__YP_007674675__Ostreococcus_lucimarinus_virus_OlV5__754064
Identity
- Accession:
- YP_007674675 ↗
- Protein ID:
- topoisomerase_2
- Kingdom:
- euk
Quality
89.5
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Megaviricetes›
Algavirales›
Phycodnaviridae›
Prasinovirus›
Ostreococcus_lucimarinus_virus_OlV5
TaxID: 754064
Cluster
View cluster (39 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 52-238
Domain cluster:
rep: IMGVR_UViG_3300039190_000305-3300039190-Ga0399989_003201_3_1937__D82-97_167-336
D2
high
residues 244-385
Domain cluster:
rep: DNA_gyrase_subunit_B__YP_009352802__Kaumoebavirus_Viruses.__X__D311-415
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00204.32 best | DNA_gyraseB | 52.9 | 4.40e-14 | 96.5% | 55.2% |
D3
high
residues 959-1071
Domain cluster:
rep: MH494197.1__AXC39168.1__X__00456__D116-252
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00521.27 best | DNA_topoisoIV | 32.8 | 5.20e-08 | 99.1% | 26.5% |
D4
medium
residues 390-542_577-602
Domain cluster:
rep: DNA_topoisomerase_2__YP_009162467__Salmon_gill_poxvirus__1680908__D385-517_553-621_640-664
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01751.29 best | Toprim | 31.5 | 2.20e-07 | 65.9% | 84.4% |
D5
medium
residues 603-667
Domain cluster:
rep: DNA_topoisomerase_II__YP_009238657__Brazilian_marseillevirus__1813599__D609-672
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF16898.11 best | TOPRIM_C | 39.6 | 8.10e-10 | 90.8% | 40.6% |
CATH (6)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3zgkA00 | 1.10.10.2460 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.60 | 44.0 | 4.30e-01 | 92.3% | 72.2% |
| 2wv2A00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.59 | 49.0 | 3.01e-01 | 95.4% | 40.4% |
| 4cq4B00 | 6.10.340.10 | Special › Helix non-globular › hypothetical protein mp506/mpn330, domain 1 › | 0.54 | 40.0 | 3.45e-01 | 100.0% | 50.0% |
| 1eniA00 | 1.10.440.10 | Mainly Alpha › Orthogonal Bundle › Endonuclease V › T4 endonuclease V | 0.53 | 43.0 | 3.56e-01 | 96.9% | 67.9% |
| 3ceiA01 | 1.10.287.990 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain | 0.52 | 39.0 | 3.96e-01 | 81.5% | 90.5% |
| 4mndA02 | 1.20.120.1760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain | 0.51 | 40.0 | 2.97e-01 | 89.2% | 38.2% |
ECOD (10)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3789608 | 2006.1.3.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain | 0.89 | 81.0 | 5.14e-01 | 100.0% | 22.9% |
| 3971654 | 1075.3.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold | 0.60 | 44.0 | 2.98e-01 | 80.0% | 95.6% |
| 3708680 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.59 | 50.0 | 3.63e-01 | 98.5% | 69.5% |
| 3170794 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.57 | 46.0 | 4.19e-01 | 90.8% | 88.9% |
| 3507297 | 109.4.1.839 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Maestro_HEAT | 0.56 | 47.0 | 3.05e-01 | 96.9% | 20.8% |
| 4603635 | 109.4.1.356 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans | 0.53 | 43.0 | 2.72e-01 | 100.0% | 34.7% |
| 3797507 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.53 | 44.0 | 3.04e-01 | 100.0% | 68.3% |
| 3667494 | 2003.1.1.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains | 0.52 | 36.0 | 2.43e-01 | 75.4% | 18.6% |
| 3806665 | 109.4.1.1495 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF26522 | 0.51 | 43.0 | 2.79e-01 | 100.0% | 56.3% |
| 3232086 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.50 | 39.0 | 3.54e-01 | 87.7% | 67.4% |
D6
medium
residues 668-797
Domain cluster:
rep: DNA_topoisomerase_2__YP_009162467__Salmon_gill_poxvirus__1680908__D669-796
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00521.27 best | DNA_topoisoIV | 164.3 | 6.30e-48 | 100.0% | 29.9% |
D7
medium
residues 848-930
Domain cluster:
rep: IMGVR_UViG_3300007985_000017-3300007985-Ga0100381_100027569__D212-299