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topoisomerase_2

Euk-Vir

Ostreococcus_lucimarinus_virus_OlV5

topoisomerase_2__YP_007674675__Ostreococcus_lucimarinus_virus_OlV5__754064

Identity

Accession:
YP_007674675 ↗
Protein ID:
topoisomerase_2
Kingdom:
euk

Quality

89.5 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 52-238
PDB
D2 high residues 244-385
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00204.32 best DNA_gyraseB 52.9 4.40e-14 96.5% 55.2%
D3 high residues 959-1071
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00521.27 best DNA_topoisoIV 32.8 5.20e-08 99.1% 26.5%
D4 medium residues 390-542_577-602
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01751.29 best Toprim 31.5 2.20e-07 65.9% 84.4%
D5 medium residues 603-667
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF16898.11 best TOPRIM_C 39.6 8.10e-10 90.8% 40.6%
CATH (6)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3zgkA00 1.10.10.2460 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.60 44.0 4.30e-01 92.3% 72.2%
2wv2A00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.59 49.0 3.01e-01 95.4% 40.4%
4cq4B00 6.10.340.10 Special › Helix non-globular › hypothetical protein mp506/mpn330, domain 1 › 0.54 40.0 3.45e-01 100.0% 50.0%
1eniA00 1.10.440.10 Mainly Alpha › Orthogonal Bundle › Endonuclease V › T4 endonuclease V 0.53 43.0 3.56e-01 96.9% 67.9%
3ceiA01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.52 39.0 3.96e-01 81.5% 90.5%
4mndA02 1.20.120.1760 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain 0.51 40.0 2.97e-01 89.2% 38.2%
ECOD (10)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3789608 2006.1.3.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain 0.89 81.0 5.14e-01 100.0% 22.9%
3971654 1075.3.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold 0.60 44.0 2.98e-01 80.0% 95.6%
3708680 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.59 50.0 3.63e-01 98.5% 69.5%
3170794 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.57 46.0 4.19e-01 90.8% 88.9%
3507297 109.4.1.839 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Maestro_HEAT 0.56 47.0 3.05e-01 96.9% 20.8%
4603635 109.4.1.356 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.53 43.0 2.72e-01 100.0% 34.7%
3797507 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.53 44.0 3.04e-01 100.0% 68.3%
3667494 2003.1.1.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.52 36.0 2.43e-01 75.4% 18.6%
3806665 109.4.1.1495 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF26522 0.51 43.0 2.79e-01 100.0% 56.3%
3232086 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.50 39.0 3.54e-01 87.7% 67.4%
D6 medium residues 668-797
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00521.27 best DNA_topoisoIV 164.3 6.30e-48 100.0% 29.9%
D7 medium residues 848-930
PDB