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transactivating_tegument_protein_VP16
Euk-VirEquid_alphaherpesvirus_9
transactivating_tegument_protein_VP16__YP_002333493__Equid_alphaherpesvirus_9__55744
Identity
- Accession:
- YP_002333493 ↗
- Protein ID:
- transactivating_tegument_protein_VP16
- Kingdom:
- euk
Quality
73.2
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Varicellovirus›
Equid_alphaherpesvirus_9
TaxID: 55744
Cluster
View cluster (32 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 57-147_162-249_335-395
Domain cluster:
representative
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02232.20 best | Alpha_TIF | 158.1 | 4.60e-46 | 75.4% | 56.0% |
| PF02232.20 | Alpha_TIF | 38.1 | 1.50e-09 | 25.8% | 17.2% |
CATH (7)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 16vpA00 | 1.10.1290.10 | Mainly Alpha › Orthogonal Bundle › Conserved core of transcriptional regulatory protein vp16 › Alpha trans-inducing (Alpha-TIF) | 0.94 | 78.0 | 6.96e-01 | 83.7% | 96.1% |
| 6xxvC00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.71 | 33.0 | 4.88e-01 | 72.5% | 96.4% |
| 1dd5A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.69 | 32.0 | 4.66e-01 | 72.5% | 95.4% |
| 4kb2A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.66 | 31.0 | 4.50e-01 | 71.7% | 96.3% |
| 3rv0C02 | 1.10.1520.10 | Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain | 0.58 | 27.0 | 3.36e-01 | 79.2% | 68.1% |
| 2a2fX02 | 1.20.58.670 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain D | 0.54 | 28.0 | 3.59e-01 | 93.3% | 86.0% |
| 7ae2A01 | 1.20.120.580 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › bsu32300-like | 0.52 | 24.0 | 3.19e-01 | 82.9% | 76.6% |
ECOD (20)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 7584 | 816.1.1.1 ↗ | a+b complex topology › Conserved core of transcriptional regulatory protein vp16 › Conserved core of transcriptional regulatory protein vp16 › Conserved core of transcriptional regulatory protein vp16 › Alpha_TIF | 0.94 | 78.0 | 7.04e-01 | 83.7% | 98.7% |
| 3524385 | 3881.1.1.2 ↗ | alpha bundles › CNOT9 binding domain CN9BD (DUF3819) › CNOT9 binding domain CN9BD (DUF3819) › CNOT9 binding domain CN9BD (DUF3819) › Codanin-1_C | 0.59 | 34.0 | 4.08e-01 | 72.5% | 83.7% |
| 5077440 | 1075.1.2.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX | 0.58 | 32.0 | 4.03e-01 | 82.1% | 88.6% |
| 5051910 | 1075.3.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold › BPD_transp_1 | 0.56 | 45.0 | 3.98e-01 | 83.3% | 88.3% |
| 3722363 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.55 | 37.0 | 4.45e-01 | 87.1% | 100.0% |
| 3286359 | 1075.3.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold › BPD_transp_1 | 0.55 | 41.0 | 4.26e-01 | 76.2% | 94.8% |
| 4574845 | 1075.3.1.4 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold › BPD_transp_1+BPD_transp_1_N | 0.55 | 43.0 | 3.93e-01 | 80.4% | 93.9% |
| 3772061 | 109.4.1.809 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Codanin-1_C | 0.55 | 31.0 | 2.73e-01 | 72.5% | 35.3% |
| 3957614 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.55 | 39.0 | 4.08e-01 | 72.9% | 88.0% |
| 4995375 | 1075.3.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold › BPD_transp_1 | 0.54 | 42.0 | 3.93e-01 | 80.4% | 95.7% |
| 4352941 | 1075.3.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold › BPD_transp_1 | 0.54 | 42.0 | 3.97e-01 | 80.4% | 96.8% |
| 3837397 | 310.2.1.57 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › DUF7798 | 0.53 | 31.0 | 3.79e-01 | 73.3% | 85.6% |
| 4951507 | 1075.1.2.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain | 0.53 | 33.0 | 3.60e-01 | 74.6% | 72.5% |
| 4230264 | 1075.3.1.4 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold › BPD_transp_1+BPD_transp_1_N | 0.53 | 41.0 | 3.69e-01 | 80.8% | 94.4% |
| 3290449 | 1075.3.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold › BPD_transp_1 | 0.53 | 41.0 | 3.96e-01 | 80.4% | 94.9% |
| 4952597 | 1075.3.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold › BPD_transp_1 | 0.52 | 42.0 | 3.92e-01 | 82.5% | 92.5% |
| 3287705 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.52 | 38.0 | 3.89e-01 | 72.9% | 81.3% |
| 5046307 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.52 | 31.0 | 3.33e-01 | 92.9% | 65.1% |
| 4931441 | 604.39.1.1 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › CbiM | 0.51 | 35.0 | 3.83e-01 | 89.6% | 82.5% |
| 3629748 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.51 | 36.0 | 3.84e-01 | 70.0% | 97.1% |
D2
medium
residues 148-161_250-334_396-411
Domain cluster:
rep: transactivating_tegument_protein_VP16__YP_009137200__Human_alphaherpesvirus_2__10310__D69-91_250-335
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02232.20 best | Alpha_TIF | 107.2 | 1.40e-30 | 85.2% | 25.7% |
D3
medium
residues 412-447