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transactivating_tegument_protein_VP16
Euk-VirTestudinid_alphaherpesvirus_3
transactivating_tegument_protein_VP16__YP_009176885__Testudinid_alphaherpesvirus_3__2560801
Identity
- Accession:
- YP_009176885 ↗
- Protein ID:
- transactivating_tegument_protein_VP16
- Kingdom:
- euk
Quality
68.7
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Scutavirus›
Testudinid_alphaherpesvirus_3
TaxID: 2560801
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 247-324
Domain cluster:
rep: transactivating_tegument_protein_VP16__YP_009252238__Canid_alphaherpesvirus_1__170325__D230-289
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02232.20 best | Alpha_TIF | 33.7 | 3.20e-08 | 87.2% | 16.3% |
D2
medium
residues 132-171_186-238_328-350
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02232.20 best | Alpha_TIF | 33.6 | 3.30e-08 | 93.1% | 28.0% |
CATH (17)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 16vpA00 | 1.10.1290.10 | Mainly Alpha › Orthogonal Bundle › Conserved core of transcriptional regulatory protein vp16 › Alpha trans-inducing (Alpha-TIF) | 0.92 | 88.0 | 6.17e-01 | 99.1% | 62.7% |
| 1t72A02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.71 | 39.0 | 4.29e-01 | 72.4% | 64.3% |
| 7e84A03 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.65 | 47.0 | 4.61e-01 | 74.1% | 100.0% |
| 4ip8A00 | 1.10.132.110 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Serum amyloid A protein | 0.65 | 38.0 | 3.96e-01 | 99.1% | 62.9% |
| 1quuA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 37.0 | 3.63e-01 | 72.4% | 51.6% |
| 2m6bA00 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.62 | 46.0 | 4.25e-01 | 78.4% | 95.3% |
| 6xxvC00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.58 | 47.0 | 4.83e-01 | 98.3% | 90.1% |
| 1dd5A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.58 | 46.0 | 4.77e-01 | 94.8% | 89.0% |
| 4kb2A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.56 | 45.0 | 4.69e-01 | 96.6% | 92.7% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.55 | 47.0 | 4.72e-01 | 98.3% | 92.3% |
| 3cf6E03 | 1.20.870.10 | Mainly Alpha › Up-down Bundle › Son of sevenless (SoS) protein; Chain S, domain 1 › Son of sevenless (SoS) protein Chain: S domain 1 | 0.55 | 35.0 | 3.35e-01 | 90.5% | 56.5% |
| 2oexA02 | 1.20.140.50 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › alix/aip1 like domains | 0.54 | 41.0 | 3.45e-01 | 79.3% | 78.7% |
| 4mh6A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.52 | 38.0 | 3.46e-01 | 76.7% | 97.5% |
| 2xubA05 | 6.10.140.1450 | Special › Helix non-globular › Helix Hairpins › | 0.52 | 36.0 | 3.89e-01 | 96.6% | 85.4% |
| 1bgfA00 | 1.10.532.10 | Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain | 0.51 | 36.0 | 3.56e-01 | 94.0% | 67.7% |
| 4hehA01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.51 | 29.0 | 3.41e-01 | 93.1% | 79.5% |
| 2i0mA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.50 | 36.0 | 3.79e-01 | 93.1% | 82.1% |
ECOD (15)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3943069 | 3291.1.1.136 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PF27688 | 0.66 | 40.0 | 3.78e-01 | 75.9% | 51.1% |
| 3772061 | 109.4.1.809 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Codanin-1_C | 0.65 | 58.0 | 4.09e-01 | 98.3% | 33.6% |
| 3501095 | 6108.1.1.0 ↗ | alpha bundles › Middle and GTPase effector domains in dynamin-related proteins › Middle and GTPase effector domains in dynamin-related proteins › Middle and GTPase effector domains in dynamin-related proteins | 0.65 | 57.0 | 3.60e-01 | 96.6% | 27.4% |
| 3483574 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.64 | 56.0 | 3.55e-01 | 96.6% | 25.4% |
| 3477521 | 3456.1.1.3 ↗ | extended segments › NADH-quinone oxidoreductase subunit A › NADH-quinone oxidoreductase subunit A › NADH-quinone oxidoreductase subunit A › OPA1_C | 0.63 | 55.0 | 5.34e-01 | 95.7% | 90.0% |
| 4590339 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.63 | 53.0 | 3.83e-01 | 91.4% | 86.3% |
| 3386694 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.56 | 51.0 | 4.17e-01 | 100.0% | 79.0% |
| 3559586 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.56 | 42.0 | 3.86e-01 | 80.2% | 60.7% |
| 3921802 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.55 | 42.0 | 3.74e-01 | 79.3% | 81.8% |
| 4930330 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.54 | 43.0 | 3.60e-01 | 84.5% | 100.0% |
| 3641196 | 5041.1.1.27 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › PRA1 | 0.54 | 38.0 | 3.89e-01 | 73.3% | 97.4% |
| 3881583 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.53 | 47.0 | 4.15e-01 | 97.4% | 83.5% |
| 3742628 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.52 | 46.0 | 4.18e-01 | 97.4% | 79.2% |
| 3653751 | 5058.1.1.11 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › TerC | 0.51 | 46.0 | 3.66e-01 | 98.3% | 60.9% |
| 3906208 | 604.7.1.12 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › TBCA_PH | 0.50 | 41.0 | 3.82e-01 | 87.1% | 93.8% |