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transcriptional_control_factor

Euk-Vir

Phascolarctid_gammaherpesvirus_1

transcriptional_control_factor__YP_010087498__Phascolarctid_gammaherpesvirus_1__2249313

Identity

Accession:: YP_010087498 ↗
Protein ID:: transcriptional_control_factor
Kingdom:: euk

Quality

73.2 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Manticavirus› Phascolarctid_gammaherpesvirus_1

TaxID: 2249313

Cluster

View cluster (20 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 252-343_462-475

PDB

Domain cluster: rep: ORF57__YP_001129410__Human_gammaherpesvirus_8__37296__D221-304

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF05459.19 best	Herpes_UL69	61.1	1.70e-16	80.2%	36.0%

CATH (7)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3mekA03	1.10.220.160	Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 ›	0.59	45.0	4.90e-01	82.1%	97.7%
4cruB00	1.25.10.10	Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant	0.57	49.0	3.63e-01	93.4%	39.6%
4hehA01	1.10.1240.10	Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain	0.57	40.0	4.37e-01	73.6%	92.8%
4v1sA00	1.50.10.20	Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase ›	0.53	43.0	3.00e-01	86.8%	34.3%
6m9sB01	1.20.910.10	Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like	0.51	43.0	3.47e-01	93.4%	92.6%
3fr3B02	1.20.1050.10	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 ›	0.51	39.0	3.81e-01	81.1%	77.4%
3lewA01	1.25.40.390	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat ›	0.51	41.0	2.95e-01	86.8%	46.9%

ECOD (4)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2418879	3977.1.1.1 ↗	alpha duplicates or obligate multimers › ICP27 homology domain › ICP27 homology domain › ICP27 homology domain › Herpes_UL69	0.90	85.0	6.09e-01	100.0%	82.1%
4983960	4995.1.1.1 ↗	alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2	0.56	39.0	4.33e-01	72.6%	100.0%
3283530	142.1.1.3 ↗	alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2	0.53	28.0	2.89e-01	75.5%	55.0%
4928408	7516.1.1.2 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2	0.51	40.0	2.82e-01	86.8%	58.1%

D2 medium residues 344-439

PDB

Domain cluster: rep: transcriptional_control_protein__NP_065556__Alcelaphine_gammaherpesvirus_1__35252__D306-423

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF05459.19 best	Herpes_UL69	64.0	2.10e-17	100.0%	44.9%

CATH (19)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1yo7A00	1.20.120.230	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like	0.72	54.0	5.02e-01	79.2%	97.5%
1rj1A00	1.20.140.40	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein	0.69	51.0	4.49e-01	79.2%	68.2%
2r5sA02	1.25.40.10	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain	0.68	47.0	4.91e-01	70.8%	79.5%
4q5nA02	1.20.1050.10	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 ›	0.65	49.0	4.74e-01	81.2%	100.0%
1sj8A02	1.20.120.230	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like	0.61	45.0	4.22e-01	78.1%	86.9%
2olpA00	1.10.490.10	Mainly Alpha › Orthogonal Bundle › Globin-like › Globins	0.59	44.0	3.88e-01	81.2%	100.0%
2f07B00	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.58	41.0	3.33e-01	74.0%	79.1%
5fglA00	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.57	41.0	3.31e-01	76.0%	80.0%
3mkrA00	1.25.40.10	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain	0.56	46.0	3.25e-01	88.5%	62.5%
4q65A00	1.20.1250.20	Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains	0.55	44.0	2.88e-01	86.5%	45.1%
4xxiA00	1.10.490.20	Mainly Alpha › Orthogonal Bundle › Globin-like › Phycocyanins	0.55	45.0	3.95e-01	89.6%	82.3%
1vluA01	3.40.605.10	Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1	0.54	46.0	3.50e-01	96.9%	59.0%
1ym3A00	3.40.1050.10	Alpha Beta › 3-Layer(aba) Sandwich › Beta-carbonic Anhydrase; Chain A › Carbonic anhydrase	0.54	44.0	3.59e-01	91.7%	81.3%
2xqyA01	3.30.500.50	Alpha Beta › 2-Layer Sandwich › Murine Class I Major Histocompatibility Complex, H2-DB; Chain A, domain 1 ›	0.54	46.0	3.83e-01	96.9%	89.9%
1s2xA00	1.20.190.30	Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › CAG pathogenicity island protein, CagZ	0.53	39.0	3.31e-01	81.2%	90.0%
3i2fA02	1.10.3020.10	Mainly Alpha › Orthogonal Bundle › alpha-amino acid ester hydrolase ( Helical cap domain) › alpha-amino acid ester hydrolase ( Helical cap domain)	0.52	38.0	3.90e-01	96.9%	80.0%
4qhpA05	1.25.50.10	Mainly Alpha › Alpha Horseshoe › Zincin-like fold › Peptidase M1, alanyl aminopeptidase, C-terminal domain	0.52	45.0	3.16e-01	99.0%	63.9%
2ddhA04	1.20.140.10	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3	0.51	39.0	3.51e-01	100.0%	59.8%
1yfmA01	1.10.275.10	Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain)	0.50	43.0	3.91e-01	100.0%	70.6%

ECOD (19)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2390527	3977.1.1.1 ↗	alpha duplicates or obligate multimers › ICP27 homology domain › ICP27 homology domain › ICP27 homology domain › Herpes_UL69	0.90	86.0	5.91e-01	100.0%	35.0%
2418879	3977.1.1.1 ↗	alpha duplicates or obligate multimers › ICP27 homology domain › ICP27 homology domain › ICP27 homology domain › Herpes_UL69	0.90	86.0	5.94e-01	100.0%	36.3%
3717847	604.1.1.0 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat	0.80	58.0	4.85e-01	76.0%	77.5%
3228302	601.1.2.0 ↗	alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608)	0.75	56.0	5.19e-01	78.1%	99.2%
3928597	633.21.1.0 ↗	alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107	0.75	56.0	4.95e-01	79.2%	85.7%
3393338	174.1.1.0 ↗	few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain	0.73	54.0	4.62e-01	78.1%	80.4%
3905848	633.23.1.0 ↗	alpha bundles › Bromodomain-like › Claudin › Claudin	0.72	54.0	4.72e-01	79.2%	76.6%
3651030	633.4.1.1 ↗	alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI	0.72	54.0	4.40e-01	79.2%	64.6%
3613860	601.1.2.105 ↗	alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Transmemb_17	0.68	51.0	4.52e-01	80.2%	85.0%
3251841	601.1.2.0 ↗	alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608)	0.63	46.0	4.20e-01	78.1%	83.7%
3436979	109.4.1.1401 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_RPAP1	0.63	46.0	3.44e-01	77.1%	54.3%
4001975	109.4.1.517 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Med24_N	0.61	52.0	3.33e-01	94.8%	100.0%
3368836	109.4.1.189 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_2	0.61	49.0	4.28e-01	86.5%	70.3%
5047547	310.2.1.0 ↗	a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF	0.59	42.0	3.97e-01	74.0%	89.6%
3642331	109.4.1.1370 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT, XMAP215_CLASP_TOG	0.59	47.0	4.22e-01	87.5%	86.7%
3397028	603.1.1.23 ↗	alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Sec20	0.58	43.0	3.56e-01	81.2%	83.6%
3473044	633.6.1.1 ↗	alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1	0.58	44.0	3.71e-01	83.3%	71.1%
3227811	5001.1.1.0 ↗	alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like	0.57	45.0	3.84e-01	100.0%	52.9%
4002586	622.4.1.31 ↗	alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › TPR_SYVN1_N	0.57	49.0	3.94e-01	97.9%	73.3%