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transcriptional_control_protein
Euk-VirAlcelaphine_gammaherpesvirus_1
transcriptional_control_protein__NP_065556__Alcelaphine_gammaherpesvirus_1__35252
Identity
- Accession:
- NP_065556 ↗
- Protein ID:
- transcriptional_control_protein
- Kingdom:
- euk
Quality
74.2
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Macavirus›
Alcelaphine_gammaherpesvirus_1
TaxID: 35252
Cluster
View cluster (20 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 216-305_424-436
Domain cluster:
rep: ORF57__YP_010084605__Macaca_nemestrina_rhadinovirus_2__123630__D216-320_435-447
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05459.19 best | Herpes_UL69 | 86.3 | 3.20e-24 | 97.1% | 41.1% |
CATH (14)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3fnrA01 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.63 | 44.0 | 3.92e-01 | 71.8% | 54.5% |
| 1rcwB00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.62 | 53.0 | 4.21e-01 | 95.1% | 93.5% |
| 1su0B00 | 3.90.1010.10 | Alpha Beta › Alpha-Beta Complex › Sufe protein. Chain: A › | 0.60 | 41.0 | 3.81e-01 | 70.9% | 99.3% |
| 1to9A00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.59 | 43.0 | 3.35e-01 | 75.7% | 92.4% |
| 5a4eC00 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.58 | 43.0 | 3.22e-01 | 77.7% | 54.0% |
| 6grjB01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.58 | 42.0 | 3.00e-01 | 75.7% | 75.6% |
| 2uubT00 | 1.20.58.110 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 | 0.56 | 39.0 | 3.99e-01 | 74.8% | 74.7% |
| 1mhyD00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.56 | 45.0 | 2.95e-01 | 89.3% | 35.7% |
| 3o7pA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.54 | 43.0 | 3.40e-01 | 87.4% | 97.7% |
| 2optA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.51 | 36.0 | 3.25e-01 | 71.8% | 53.5% |
| 1b5lA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.51 | 40.0 | 3.51e-01 | 82.5% | 66.4% |
| 2yhwA02 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.51 | 37.0 | 3.19e-01 | 76.7% | 60.4% |
| 2pusA04 | 6.10.140.300 | Special › Helix non-globular › Helix Hairpins › | 0.50 | 40.0 | 3.96e-01 | 84.5% | 87.0% |
| 7zghA01 | 3.40.50.1240 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphoglycerate mutase-like | 0.50 | 44.0 | 2.95e-01 | 97.1% | 92.1% |
ECOD (14)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2390527 | 3977.1.1.1 ↗ | alpha duplicates or obligate multimers › ICP27 homology domain › ICP27 homology domain › ICP27 homology domain › Herpes_UL69 | 0.94 | 89.0 | 6.22e-01 | 98.1% | 78.2% |
| 2418879 | 3977.1.1.1 ↗ | alpha duplicates or obligate multimers › ICP27 homology domain › ICP27 homology domain › ICP27 homology domain › Herpes_UL69 | 0.93 | 89.0 | 6.24e-01 | 99.0% | 81.0% |
| 1562404 | 3977.1.1.1 ↗ | alpha duplicates or obligate multimers › ICP27 homology domain › ICP27 homology domain › ICP27 homology domain › Herpes_UL69 | 0.83 | 78.0 | 5.54e-01 | 98.1% | 60.4% |
| 3567382 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.68 | 48.0 | 4.63e-01 | 72.8% | 93.0% |
| 3512422 | 109.4.1.869 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › INT1_R3 | 0.66 | 53.0 | 4.59e-01 | 87.4% | 58.1% |
| 5021452 | 5048.1.1.7 ↗ | alpha complex topology › Aquaporin-like › Aquaporin-like › Aquaporin-like › DUF389 | 0.60 | 43.0 | 3.33e-01 | 75.7% | 64.6% |
| 3960897 | 191.1.1.0 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain | 0.56 | 39.0 | 3.59e-01 | 72.8% | 72.5% |
| 3599441 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.56 | 45.0 | 3.45e-01 | 87.4% | 71.0% |
| 5022203 | 5082.1.1.5 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › DUF389 | 0.56 | 45.0 | 3.45e-01 | 86.4% | 88.9% |
| 4196666 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.54 | 44.0 | 3.48e-01 | 87.4% | 88.8% |
| 3423539 | 109.4.1.153 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › FANCF | 0.53 | 40.0 | 3.21e-01 | 87.4% | 39.0% |
| 4166810 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.53 | 41.0 | 3.30e-01 | 81.6% | 91.3% |
| 161422 | 191.1.1.42 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_41 | 0.52 | 36.0 | 3.49e-01 | 72.8% | 70.8% |
| 5014402 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.51 | 39.0 | 3.25e-01 | 82.5% | 90.8% |
D2
medium
residues 306-423
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05459.19 best | Herpes_UL69 | 85.6 | 5.10e-24 | 100.0% | 53.7% |
CATH (15)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4dloB02 | 1.25.40.610 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.63 | 45.0 | 4.59e-01 | 73.7% | 81.2% |
| 3fp3A01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.58 | 42.0 | 4.00e-01 | 75.4% | 64.4% |
| 1e52A00 | 4.10.860.10 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › UVR domain | 0.57 | 27.0 | 3.59e-01 | 73.7% | 89.3% |
| 5tqbB01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.56 | 50.0 | 3.65e-01 | 99.2% | 51.8% |
| 1yo7A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.55 | 40.0 | 4.02e-01 | 100.0% | 73.3% |
| 3vadA01 | 1.20.140.20 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain | 0.55 | 40.0 | 3.64e-01 | 100.0% | 56.4% |
| 1sqmA04 | 1.25.40.320 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal domain | 0.55 | 40.0 | 3.69e-01 | 75.4% | 69.1% |
| 2xubA05 | 6.10.140.1450 | Special › Helix non-globular › Helix Hairpins › | 0.55 | 28.0 | 3.08e-01 | 79.7% | 58.3% |
| 1vctA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.54 | 34.0 | 3.55e-01 | 93.2% | 67.9% |
| 5an3A01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.54 | 45.0 | 4.37e-01 | 89.8% | 93.8% |
| 2kw6A00 | 6.10.140.1300 | Special › Helix non-globular › Helix Hairpins › | 0.54 | 27.0 | 3.39e-01 | 75.4% | 83.1% |
| 1kmiZ02 | 1.10.287.500 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.54 | 32.0 | 3.10e-01 | 83.1% | 51.5% |
| 1t72A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.53 | 35.0 | 3.59e-01 | 94.1% | 67.5% |
| 2fozA00 | 1.10.4080.10 | Mainly Alpha › Orthogonal Bundle › ADP-ribosylglycohydrolase fold › ADP-ribosylation/Crystallin J1 | 0.52 | 45.0 | 3.31e-01 | 96.6% | 87.6% |
| 1t98A02 | 1.20.58.590 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain | 0.51 | 38.0 | 3.48e-01 | 79.7% | 95.1% |
ECOD (15)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2418879 | 3977.1.1.1 ↗ | alpha duplicates or obligate multimers › ICP27 homology domain › ICP27 homology domain › ICP27 homology domain › Herpes_UL69 | 0.91 | 87.0 | 6.39e-01 | 100.0% | 44.0% |
| 2390527 | 3977.1.1.1 ↗ | alpha duplicates or obligate multimers › ICP27 homology domain › ICP27 homology domain › ICP27 homology domain › Herpes_UL69 | 0.89 | 85.0 | 6.23e-01 | 100.0% | 42.5% |
| 4180004 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.65 | 47.0 | 4.15e-01 | 74.6% | 75.9% |
| 5041952 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.61 | 42.0 | 4.09e-01 | 71.2% | 100.0% |
| 3721237 | 109.4.1.1255 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Adaptin_N, Cnd1 | 0.61 | 44.0 | 3.71e-01 | 74.6% | 70.3% |
| 3392973 | 109.4.1.32 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MIF4G | 0.59 | 43.0 | 3.12e-01 | 76.3% | 51.5% |
| 3379886 | 604.12.1.85 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › 14-3-3 | 0.58 | 32.0 | 3.50e-01 | 92.4% | 64.9% |
| 3634571 | 109.4.1.1241 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HIR3_bundle | 0.57 | 50.0 | 3.70e-01 | 99.2% | 73.3% |
| 3638003 | 109.4.1.97 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_2,TPR_12 | 0.57 | 47.0 | 3.37e-01 | 89.8% | 37.8% |
| 1406322 | 109.4.1.2096 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_6, TPR_19, PF30363, PF30475 | 0.57 | 41.0 | 2.65e-01 | 77.1% | 54.0% |
| 3599624 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.56 | 44.0 | 2.85e-01 | 84.7% | 51.7% |
| 3942717 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.56 | 47.0 | 4.38e-01 | 92.4% | 89.3% |
| 3243589 | 109.4.1.590 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › NopRA1 | 0.55 | 43.0 | 2.92e-01 | 84.7% | 61.1% |
| 3995294 | 1065.1.1.0 ↗ | alpha bundles › SPX domain › SPX domain › SPX domain | 0.54 | 39.0 | 3.86e-01 | 74.6% | 87.2% |
| 5073131 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.50 | 38.0 | 3.85e-01 | 80.5% | 95.8% |