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transcriptional_regulator_ICP4

Euk-Vir

Chimpanzee_herpesvirus_strain_105640

transcriptional_regulator_ICP4__YP_009011047__Chimpanzee_herpesvirus_strain_105640__332937

Identity

Accession:: YP_009011047 ↗
Protein ID:: transcriptional_regulator_ICP4
Kingdom:: euk

Quality

60.8 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Simplexvirus› Chimpanzee_herpesvirus_strain_105640

TaxID: 332937

Cluster

View cluster (8 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 313-504

PDB

Domain cluster: rep: hypothetical_protein__YP_009230205__Leporid_alphaherpesvirus_4__481315__D118-301

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03584.21 best	Herpes_ICP4_N	279.4	1.60e-83	90.1%	100.0%

D2 high residues 546-558_578-623_639-737

PDB

Domain cluster: rep: transcriptional_regulator_ICP4__YP_009137226__Human_alphaherpesvirus_2__10310__D637-670_685-768

D3 medium residues 833-887

PDB

Domain cluster: rep: transcriptional_regulator_ICP4__NP_851933__Macacine_alphaherpesvirus_1__10325__D749-813

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03585.20 best	Herpes_ICP4_C	69.1	4.60e-19	94.5%	10.1%

D4 medium residues 888-935_953-1024

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03585.20 best	Herpes_ICP4_C	173.6	9.10e-51	100.0%	30.4%

CATH (9)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3ffrA02	3.40.640.10	Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain)	0.59	33.0	2.63e-01	96.7%	26.7%
3crmA01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.58	40.0	3.75e-01	85.0%	56.6%
2c81A01	3.40.640.10	Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain)	0.57	34.0	2.67e-01	97.5%	28.2%
1lluA02	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.56	32.0	3.09e-01	85.0%	46.4%
6ouvA03	3.40.50.920	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.54	38.0	3.69e-01	98.3%	65.2%
2o1sB03	3.40.50.920	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.52	36.0	3.59e-01	98.3%	66.9%
2afbB00	3.40.1190.20	Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase	0.52	42.0	3.08e-01	85.8%	56.4%
3sc6A02	3.90.25.10	Alpha Beta › Alpha-Beta Complex › UDP-galactose 4-epimerase; domain 1 › UDP-galactose 4-epimerase, domain 1	0.51	24.0	2.91e-01	81.7%	63.6%
1gg1A00	3.20.20.70	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I	0.50	42.0	3.10e-01	93.3%	87.9%

ECOD (11)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3273876	7569.1.1.0 ↗	a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like	0.66	61.0	4.76e-01	100.0%	66.1%
3673420	7514.1.1.1 ↗	a/b three-layered sandwiches › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › NAD_binding_1	0.60	30.0	3.39e-01	91.7%	61.1%
4946402	2006.1.3.11 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › TOP6A-Spo11_Toprim	0.56	40.0	3.42e-01	85.8%	46.6%
3588059	247.1.1.24 ↗	a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B+Lactamase_B_2	0.55	40.0	3.10e-01	74.2%	94.1%
4982215	247.1.1.11 ↗	a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_2	0.55	40.0	3.19e-01	75.8%	96.9%
4994367	2004.1.1.123 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_RecD	0.53	39.0	3.31e-01	75.8%	80.0%
3481159	2007.2.3.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II	0.53	41.0	2.95e-01	82.5%	53.7%
4244185	7522.1.1.1 ↗	a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › Transketolase_C	0.52	39.0	3.80e-01	100.0%	71.1%
4229738	2006.1.3.0 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain	0.50	33.0	3.38e-01	90.0%	69.0%
3703483	2004.1.1.135 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › PIF1	0.50	28.0	2.28e-01	95.0%	25.1%
4326257	2006.1.3.7 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim_4	0.50	32.0	3.36e-01	90.0%	69.0%

D5 medium residues 936-952_1025-1087

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03585.20 best	Herpes_ICP4_C	94.8	7.10e-27	80.0%	14.2%

CATH (1)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1o7dC01	1.20.1270.50	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Glycoside hydrolase family 38, central domain	0.51	33.0	3.67e-01	81.2%	85.2%

D6 medium residues 1100-1229

PDB