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transmembrane_domain-containing_protein

Euk-Vir

Noumeavirus

transmembrane_domain-containing_protein__YP_009345255__Noumeavirus__1955558

Identity

Accession:
YP_009345255 ↗
Protein ID:
transmembrane_domain-containing_protein
Kingdom:
euk

Quality

81.7 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 20-57_181-205
PDB
Domain cluster: representative
CATH (54)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4mrsA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.78 69.0 4.32e-01 100.0% 34.5%
2xubA05 6.10.140.1450 Special › Helix non-globular › Helix Hairpins › 0.78 70.0 6.03e-01 100.0% 94.8%
4abmD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.77 65.0 6.13e-01 93.7% 100.0%
1qsdA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.76 67.0 5.70e-01 100.0% 75.5%
2mtqA00 1.20.58.130 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.75 52.0 4.98e-01 100.0% 63.0%
1y1uA01 1.20.1050.20 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain 0.75 65.0 4.64e-01 100.0% 51.3%
1gpjA03 1.10.1200.70 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Glutamyl tRNA-reductase dimerization domain 0.75 56.0 5.10e-01 81.0% 77.6%
2uv8A07 6.10.140.1410 Special › Helix non-globular › Helix Hairpins › 0.74 62.0 5.62e-01 92.1% 81.2%
3icxA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.74 64.0 6.11e-01 98.4% 100.0%
6r1nA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.74 64.0 5.53e-01 100.0% 75.7%
2xokP00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.74 65.0 6.20e-01 100.0% 86.5%
4aflA00 6.10.140.1740 Special › Helix non-globular › Helix Hairpins › 0.73 65.0 5.54e-01 100.0% 73.5%
1h7cA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.73 63.0 5.43e-01 100.0% 81.6%
1u7lA02 1.20.1460.10 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 0.73 62.0 4.55e-01 100.0% 50.3%
2vkzA02 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.73 64.0 4.24e-01 100.0% 82.8%
1vctA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.72 64.0 5.30e-01 100.0% 56.9%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.72 62.0 5.26e-01 100.0% 70.9%
4g6dB02 6.10.140.1800 Special › Helix non-globular › Helix Hairpins › 0.72 62.0 5.74e-01 98.4% 100.0%
2dq0A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.71 63.0 5.33e-01 100.0% 61.7%
1wp7A00 1.10.287.770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like 0.71 63.0 6.32e-01 98.4% 96.9%
3favD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.71 61.0 5.78e-01 98.4% 100.0%
3l9fA02 6.10.140.1570 Special › Helix non-globular › Helix Hairpins › 0.71 59.0 5.39e-01 90.5% 79.0%
3fd9A03 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.70 61.0 5.83e-01 100.0% 83.6%
1x0tA01 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.70 54.0 5.48e-01 81.0% 88.5%
1jadA00 1.20.1230.10 Mainly Alpha › Up-down Bundle › Phospholipase C Beta; Chain: A › Phospholipase C beta, distal C-terminal domain 0.70 61.0 4.12e-01 100.0% 44.6%
3hr0B01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.70 62.0 5.79e-01 100.0% 79.7%
3r84A00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.69 60.0 5.55e-01 100.0% 90.1%
1skvA00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.67 60.0 5.97e-01 100.0% 100.0%
1x4tA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.67 55.0 5.71e-01 100.0% 100.0%
1uurA01 1.20.58.240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 0.67 59.0 4.89e-01 98.4% 59.1%
1urfA00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.66 55.0 5.14e-01 95.2% 95.1%
2wzkA03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.66 53.0 4.45e-01 88.9% 57.3%
3mq1A01 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 59.0 5.22e-01 100.0% 71.7%
1a7eA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.66 50.0 4.12e-01 87.3% 44.1%
3e22A03 1.10.287.600 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.66 50.0 5.31e-01 100.0% 94.4%
4nb5B02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.66 55.0 5.52e-01 100.0% 93.8%
1td6A03 1.10.472.40 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Hypothetical protein mg237 homolog; domain 3 0.65 44.0 3.89e-01 92.1% 47.8%
1rfyB00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.65 55.0 4.98e-01 100.0% 68.2%
2rp4A00 6.10.280.60 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Transcription factor p53, C-terminal domain 0.65 47.0 4.52e-01 76.2% 67.6%
4l8jA04 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.65 53.0 5.44e-01 90.5% 96.6%
1vf7A03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.64 53.0 5.46e-01 93.7% 100.0%
3ns4A00 1.10.357.110 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Vacuolar protein sorting-associated protein 53, C-terminus 0.64 54.0 3.88e-01 100.0% 31.7%
1wncB00 1.20.5.300 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.64 55.0 5.11e-01 100.0% 77.8%
2j5iA02 6.10.250.2850 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.63 38.0 4.51e-01 93.7% 100.0%
4okvE00 6.10.140.1890 Special › Helix non-globular › Helix Hairpins › 0.63 54.0 5.43e-01 100.0% 96.9%
4e6nA02 6.10.140.1010 Special › Helix non-globular › Helix Hairpins › 0.62 53.0 5.28e-01 95.2% 90.9%
2lw1A00 1.10.287.380 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain 0.62 54.0 4.97e-01 100.0% 83.5%
7c1iA01 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.62 54.0 4.66e-01 100.0% 92.0%
3zsuA00 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.59 50.0 4.16e-01 100.0% 99.2%
1t33A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.58 50.0 3.79e-01 100.0% 81.6%
8igrI01 2.40.270.10 Mainly Beta › Beta Barrel › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6 › DNA-directed RNA polymerase, subunit 2, domain 6 0.56 46.0 3.35e-01 90.5% 82.4%
1wfdA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.55 41.0 3.80e-01 100.0% 59.1%
4u2vA02 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.55 37.0 3.49e-01 82.5% 55.0%
2zgyA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.53 45.0 3.60e-01 100.0% 58.6%
ECOD (44)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4052085 150.8.1.4 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PPE › PPE › Hydro_N_hd 0.79 71.0 4.86e-01 100.0% 46.7%
4960548 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.79 70.0 5.00e-01 100.0% 47.2%
3880637 3755.3.1.465 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF21A 0.77 68.0 5.29e-01 100.0% 62.1%
5051528 2004.1.1.85 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ArsA_ATPase 0.76 62.0 3.87e-01 100.0% 17.0%
4263341 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.76 66.0 5.32e-01 100.0% 51.3%
3376917 192.24.1.8 alpha bundles › Long alpha-hairpin › RPC62 helical hairpin domain › RPC62 helical hairpin domain › CDK5RAP3 0.76 62.0 5.72e-01 88.9% 100.0%
4257134 192.5.1.35 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › Hobbit 0.76 67.0 5.78e-01 100.0% 76.0%
3691415 2004.1.1.748 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_15, AAA_23, SbcC_Walker_B 0.76 67.0 3.91e-01 100.0% 13.1%
4654983 605.2.1.3 alpha duplicates or obligate multimers › ROP-like › Hypothetical protein D-63 › Hypothetical protein D-63 › Seryl_tRNA_N 0.75 63.0 5.25e-01 100.0% 53.6%
3973636 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.74 66.0 6.26e-01 100.0% 97.3%
5005097 3710.1.1.0 alpha bundles › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain 0.72 65.0 5.07e-01 100.0% 49.6%
4499889 192.24.1.1 alpha bundles › Long alpha-hairpin › RPC62 helical hairpin domain › RPC62 helical hairpin domain › RPC3_helical 0.72 65.0 5.69e-01 100.0% 87.1%
5056477 5058.1.1.2 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st 0.72 62.0 5.45e-01 96.8% 65.6%
3948872 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.72 64.0 5.06e-01 100.0% 56.2%
4120406 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.72 64.0 5.30e-01 100.0% 60.9%
4385365 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.72 62.0 5.23e-01 100.0% 66.4%
185321 109.4.1.262 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › COG4_C 0.71 62.0 4.17e-01 100.0% 33.6%
3504922 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.71 59.0 5.51e-01 93.7% 97.5%
4954843 604.5.1.2 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.71 63.0 5.46e-01 100.0% 65.3%
4009031 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.70 60.0 5.50e-01 100.0% 94.1%
4952853 5058.1.1.2 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st 0.70 61.0 5.31e-01 96.8% 64.2%
3491110 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.70 59.0 5.06e-01 100.0% 67.3%
2409294 601.52.1.1 alpha bundles › Four-helical up-and-down bundle › Flagellar hook-associated protein 1 helical domain › Flagellar hook-associated protein 1 helical domain › Flagellin_N 0.69 60.0 4.66e-01 95.2% 83.7%
4958384 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.69 57.0 5.11e-01 92.1% 78.9%
4460898 2003.1.1.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.69 61.0 3.98e-01 96.8% 25.4%
4025710 3871.1.1.0 alpha duplicates or obligate multimers › PHIST › PHIST › PHIST 0.69 60.0 4.86e-01 100.0% 63.2%
4349607 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.69 61.0 5.09e-01 100.0% 60.0%
3967813 5086.1.1.93 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_EMRA 0.69 61.0 4.81e-01 100.0% 48.5%
4045132 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.69 61.0 5.07e-01 100.0% 87.3%
4222581 547.1.1.1 alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer 0.68 59.0 4.89e-01 95.2% 58.2%
3712805 129.1.1.16 alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › NAD_binding_11 0.68 48.0 3.48e-01 73.0% 30.0%
3470897 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.68 58.0 4.29e-01 100.0% 36.8%
3561223 5021.1.1.0 extended segments › Subunit IX of photosystem I reaction centre, PsaJ › Subunit IX of photosystem I reaction centre, PsaJ › Subunit IX of photosystem I reaction centre, PsaJ 0.68 57.0 5.35e-01 100.0% 75.0%
3505608 192.29.1.1 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB_dom 0.67 58.0 5.54e-01 100.0% 84.0%
1675309 601.51.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-helical domain in phase 1 flagellin › alpha-helical domain in phase 1 flagellin › Flagellin_N 0.67 60.0 5.12e-01 100.0% 73.0%
5060252 632.23.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Helical linker domain in nicking endonuclease N.BspD6I › Helical linker domain in nicking endonuclease N.BspD6I 0.66 52.0 4.79e-01 98.4% 64.7%
4575830 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.66 53.0 3.18e-01 88.9% 13.3%
4291487 1128.1.1.2 alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR_2 0.66 45.0 3.76e-01 76.2% 40.9%
3386973 5086.1.1.84 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.66 57.0 5.15e-01 100.0% 70.0%
4946455 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.64 55.0 5.14e-01 100.0% 78.8%
4945751 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.64 56.0 4.70e-01 100.0% 57.3%
3965415 3827.1.1.1 alpha duplicates or obligate multimers › Hypothetical protein PA0856 › Hypothetical protein PA0856 › Hypothetical protein PA0856 › DUF2059 0.64 49.0 4.05e-01 85.7% 51.7%
3617518 632.15.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) 0.63 48.0 4.65e-01 81.0% 74.3%
3968484 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.62 53.0 5.20e-01 100.0% 100.0%