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transmembrane_domain-containing_protein

Euk-Vir

Noumeavirus

transmembrane_domain-containing_protein__YP_009345323__Noumeavirus__1955558

Identity

Accession:: YP_009345323 ↗
Protein ID:: transmembrane_domain-containing_protein
Kingdom:: euk

Quality

73.9 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Megaviricetes› Pimascovirales› Marseilleviridae› Marseillevirus› Noumeavirus

TaxID: 1955558

Cluster

Singleton — not in a non-trivial cluster

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 16-132_287-344

PDB

Domain cluster: rep: conserved_putative_glycosyltransferase__YP_009094754__Melbournevirus__1560514__D7-144_250-270_296-310

CATH (16)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1st6A02	1.20.120.810	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle	0.69	43.0	3.93e-01	96.6%	46.6%
5b00A00	1.10.600.10	Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase	0.59	45.0	3.99e-01	78.9%	83.5%
6kd7A00	1.10.600.10	Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase	0.59	45.0	3.69e-01	78.9%	89.3%
2jlnA00	1.10.4160.10	Mainly Alpha › Orthogonal Bundle › Hydantoin permease › Hydantoin permease	0.59	46.0	3.41e-01	81.7%	87.0%
3ucaA00	1.10.600.10	Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase	0.58	44.0	3.88e-01	80.0%	87.2%
3tc1B00	1.10.600.10	Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase	0.58	45.0	3.73e-01	79.4%	58.7%
5eroA00	1.10.600.10	Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase	0.58	44.0	3.69e-01	79.4%	94.0%
3dbyL00	1.20.1260.120	Mainly Alpha › Up-down Bundle › Ferritin › Protein of unknown function DUF2935	0.57	43.0	3.79e-01	78.3%	86.5%
3aqbA00	1.20.120.1450	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) ›	0.56	37.0	4.16e-01	71.4%	84.4%
1orsC00	1.20.120.350	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C	0.53	37.0	4.16e-01	96.0%	93.2%
7zd5C01	1.20.1560.10	Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain	0.52	38.0	3.18e-01	75.4%	84.5%
3caxA01	1.20.120.520	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like	0.52	47.0	4.34e-01	97.1%	86.2%
3axjB01	1.20.58.190	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1	0.52	32.0	3.42e-01	76.0%	69.0%
6c1qB02	1.20.1070.10	Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins	0.52	40.0	3.42e-01	80.6%	72.4%
4od4A01	1.10.357.140	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › UbiA prenyltransferase	0.51	36.0	3.80e-01	70.9%	99.4%
7w9wA01	1.20.1070.10	Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins	0.51	39.0	3.47e-01	82.3%	96.2%

ECOD (21)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
5075952	601.1.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin	0.68	47.0	5.39e-01	95.4%	95.3%
4580475	3684.1.1.28 ↗	alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PF26154	0.66	44.0	5.06e-01	94.3%	92.8%
3827837	611.9.1.2 ↗	alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › RPW8	0.63	36.0	4.31e-01	82.9%	83.5%
3971025	601.4.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains	0.62	42.0	4.90e-01	94.3%	96.0%
3760737	601.16.1.17 ↗	alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › PF27561	0.62	46.0	5.06e-01	94.9%	95.7%
4956823	5069.1.1.3 ↗	alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cyt_bd_oxida_I	0.62	53.0	3.95e-01	91.4%	92.1%
2841860	601.4.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains	0.60	43.0	4.74e-01	96.0%	90.2%
4987504	192.29.1.299 ↗	alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › HepT-like	0.60	39.0	4.55e-01	95.4%	94.1%
4930083	141.1.1.1 ↗	alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › polyprenyl_synt	0.60	46.0	3.77e-01	79.4%	59.1%
4957307	141.1.1.1 ↗	alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › polyprenyl_synt	0.59	45.0	3.63e-01	78.9%	88.2%
3662351	611.9.1.4 ↗	alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N	0.58	36.0	4.15e-01	82.9%	85.6%
3888840	5059.1.1.1 ↗	alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA	0.57	41.0	3.39e-01	72.0%	90.8%
4033272	192.8.1.0 ↗	alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain	0.56	32.0	3.83e-01	96.0%	81.7%
4964919	7064.1.1.1 ↗	alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1	0.55	39.0	3.88e-01	71.4%	90.2%
4177197	5059.1.1.9 ↗	alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Sugar_transport	0.55	38.0	3.26e-01	70.3%	84.4%
4607769	6151.1.1.1 ↗	alpha bundles › Helical bundle domain in S46 peptidase › Helical bundle domain in S46 peptidase › Helical bundle domain in S46 peptidase › Peptidase_S46	0.53	38.0	3.17e-01	72.0%	83.1%
3737856	196.1.1.1 ↗	alpha bundles › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › RGS	0.52	36.0	3.81e-01	96.0%	78.1%
3904807	5001.1.1.1 ↗	alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1	0.52	41.0	3.27e-01	82.3%	61.2%
3704183	5050.1.1.9 ↗	alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1	0.52	43.0	4.01e-01	100.0%	71.6%
5024741	5051.1.1.9 ↗	alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Transp_cyt_pur	0.51	45.0	3.33e-01	94.9%	84.2%
3652864	5076.1.1.1 ↗	alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr	0.51	39.0	3.29e-01	78.9%	89.3%

D2 medium residues 135-243_345-370

PDB

Domain cluster: representative

CATH (2)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1q8cA00	1.10.940.10	Mainly Alpha › Orthogonal Bundle › N-utilizing Substance Protein B Homolog; Chain A › NusB-like	0.52	39.0	3.94e-01	77.0%	100.0%
1ca1A01	1.10.575.10	Mainly Alpha › Orthogonal Bundle › P1 Nuclease › P1 Nuclease	0.50	39.0	3.10e-01	80.0%	82.0%

D3 medium residues 371-501

PDB

D4 medium residues 502-624

PDB

Domain cluster: rep: glycosyltransferase__YP_003407018__Marseillevirus_marseillevirus__694581__D509-628