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tyrosine_kinase
Euk-VirAnopheles_minimus_iridovirus
tyrosine_kinase__YP_009021181__Anopheles_minimus_iridovirus__1465751
Identity
- Accession:
- YP_009021181 ↗
- Protein ID:
- tyrosine_kinase
- Kingdom:
- euk
Quality
70.1
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Megaviricetes›
Pimascovirales›
Iridoviridae›
Chloriridovirus›
Chloriridovirus_anopheles1
TaxID: 1465751
Cluster
View cluster (5 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 39-160
D2
high
residues 165-351
Domain cluster:
rep: Ser_Thr_protein_kinase__YP_009325839__Only_Syngen_Nebraska_virus_5__1917232__D131-313
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05445.18 best | Pox_ser-thr_kin | 27.4 | 2.40e-06 | 93.6% | 21.0% |
| PF12330.15 | Haspin_kinase | 27.2 | 2.90e-06 | 88.8% | 22.5% |
CATH (37)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4qtcA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.73 | 66.0 | 6.64e-01 | 95.7% | 99.0% |
| 4otpA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.73 | 45.0 | 5.13e-01 | 95.2% | 81.1% |
| 7szaA01 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.69 | 45.0 | 5.45e-01 | 87.7% | 97.6% |
| 4ix3A02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.67 | 61.0 | 5.64e-01 | 96.8% | 97.0% |
| 3m2wA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.66 | 54.0 | 5.36e-01 | 97.3% | 82.1% |
| 1yhsA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.65 | 57.0 | 5.79e-01 | 98.9% | 93.9% |
| 3gniB02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.64 | 57.0 | 5.61e-01 | 98.4% | 89.3% |
| 1yhvA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.63 | 57.0 | 5.68e-01 | 98.4% | 91.3% |
| 5l2qB02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.63 | 58.0 | 5.77e-01 | 97.3% | 93.3% |
| 2rioA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.63 | 57.0 | 5.78e-01 | 95.7% | 98.4% |
| 4g3dB02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.63 | 58.0 | 5.77e-01 | 97.9% | 96.4% |
| 6ziwI02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.63 | 57.0 | 5.86e-01 | 96.8% | 100.0% |
| 3c0iA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.63 | 57.0 | 5.53e-01 | 97.3% | 89.5% |
| 1tkiA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.63 | 57.0 | 5.25e-01 | 97.3% | 77.2% |
| 4c0tA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.62 | 58.0 | 5.74e-01 | 98.4% | 96.4% |
| 4nfnA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.62 | 58.0 | 5.62e-01 | 98.4% | 95.1% |
| 5f9eB02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.62 | 56.0 | 5.42e-01 | 99.5% | 86.8% |
| 2wtkC02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.62 | 57.0 | 5.65e-01 | 97.3% | 92.9% |
| 1tr8A01 | 2.20.70.30 | Mainly Beta › Single Sheet › Ubiquitin Ligase Nedd4; Chain: W; › Nascent polypeptide-associated complex domain | 0.62 | 18.0 | 3.39e-01 | 76.5% | 90.4% |
| 4y85A02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.62 | 56.0 | 5.75e-01 | 96.3% | 99.4% |
| 3is5F02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.61 | 54.0 | 5.62e-01 | 96.8% | 99.4% |
| 1csnA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.61 | 57.0 | 5.45e-01 | 98.4% | 95.3% |
| 4eutB02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.61 | 55.0 | 5.28e-01 | 94.1% | 99.5% |
| 3oz6B02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.61 | 58.0 | 5.33e-01 | 100.0% | 92.7% |
| 4krdA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.61 | 57.0 | 5.52e-01 | 99.5% | 100.0% |
| 4uyaA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.61 | 52.0 | 5.18e-01 | 96.8% | 85.3% |
| 8jpdG02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.61 | 57.0 | 5.55e-01 | 100.0% | 90.8% |
| 6fdyU02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.61 | 55.0 | 5.61e-01 | 99.5% | 98.3% |
| 1phkA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.61 | 56.0 | 5.66e-01 | 99.5% | 98.4% |
| 6qavC02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.61 | 55.0 | 5.61e-01 | 96.3% | 100.0% |
| 2h96A02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.61 | 57.0 | 5.40e-01 | 100.0% | 98.2% |
| 1j3hA01 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.61 | 55.0 | 5.25e-01 | 99.5% | 84.6% |
| 7zvsA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.60 | 54.0 | 5.56e-01 | 94.1% | 100.0% |
| 8hk0B03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.60 | 29.0 | 3.30e-01 | 98.4% | 60.1% |
| 2zmdA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.59 | 51.0 | 5.36e-01 | 96.3% | 100.0% |
| 7aqbB02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.55 | 51.0 | 5.07e-01 | 97.3% | 100.0% |
| 1r2jA01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.53 | 30.0 | 3.85e-01 | 94.7% | 97.1% |
ECOD (31)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3241635 | 206.1.1.28 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase | 0.82 | 60.0 | 6.41e-01 | 98.9% | 85.5% |
| 3222568 | 206.1.1.28 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase | 0.81 | 59.0 | 5.17e-01 | 96.8% | 52.2% |
| 3227288 | 206.1.1.28 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase | 0.81 | 59.0 | 6.01e-01 | 97.3% | 76.7% |
| 3230153 | 206.1.1.28 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase | 0.79 | 60.0 | 5.31e-01 | 98.9% | 56.5% |
| 3231695 | 206.1.1.28 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase | 0.79 | 57.0 | 4.87e-01 | 94.1% | 47.6% |
| 3242068 | 206.1.1.28 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase | 0.78 | 57.0 | 5.01e-01 | 97.3% | 51.9% |
| 3216195 | 206.1.1.28 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase | 0.78 | 58.0 | 5.07e-01 | 98.4% | 53.0% |
| 377116 | 206.1.1.28 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase | 0.73 | 66.0 | 5.27e-01 | 95.7% | 53.6% |
| 3412722 | 206.1.1.28 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase | 0.72 | 64.0 | 5.04e-01 | 92.0% | 51.4% |
| 3791557 | 206.1.1.28 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase | 0.72 | 68.0 | 5.36e-01 | 100.0% | 52.5% |
| 3512772 | 206.1.1.28 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase | 0.72 | 68.0 | 6.10e-01 | 99.5% | 75.5% |
| 3926228 | 206.1.1.28 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase | 0.72 | 66.0 | 5.30e-01 | 97.3% | 53.3% |
| 3485481 | 206.1.1.28 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase | 0.71 | 67.0 | 5.08e-01 | 98.9% | 55.0% |
| 3481008 | 206.1.1.28 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase | 0.71 | 67.0 | 5.35e-01 | 100.0% | 55.0% |
| 3271955 | 206.1.1.28 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase | 0.70 | 67.0 | 4.74e-01 | 100.0% | 50.3% |
| 3740166 | 206.1.1.28 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase | 0.69 | 63.0 | 4.96e-01 | 95.2% | 61.7% |
| 3686862 | 206.1.1.28 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase | 0.68 | 64.0 | 4.82e-01 | 100.0% | 60.2% |
| 3593083 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.67 | 62.0 | 4.36e-01 | 97.3% | 62.8% |
| 4013490 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.67 | 63.0 | 4.76e-01 | 100.0% | 59.5% |
| 3186307 | 206.1.1.28 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase | 0.66 | 62.0 | 4.81e-01 | 100.0% | 58.5% |
| 3706195 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.66 | 60.0 | 4.82e-01 | 97.3% | 60.0% |
| 3170528 | 206.1.1.28 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase | 0.66 | 60.0 | 4.95e-01 | 95.2% | 59.7% |
| 3197551 | 206.1.1.28 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase | 0.65 | 61.0 | 4.61e-01 | 100.0% | 58.1% |
| 3599006 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.63 | 60.0 | 4.95e-01 | 100.0% | 67.0% |
| 3715317 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.63 | 58.0 | 4.58e-01 | 97.3% | 57.3% |
| 3181363 | 206.1.1.72 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, Pkinase_fungal | 0.63 | 60.0 | 4.98e-01 | 100.0% | 62.6% |
| 3683670 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.63 | 59.0 | 4.80e-01 | 98.9% | 66.0% |
| 4020559 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.61 | 56.0 | 4.52e-01 | 96.8% | 69.6% |
| 3171544 | 206.1.1.71 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, Kdo | 0.61 | 57.0 | 4.73e-01 | 100.0% | 68.3% |
| 3744034 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.59 | 54.0 | 4.33e-01 | 97.3% | 52.0% |
| 4408522 | 389.1.2.1 ↗ | few secondary structure elements › EGF-like › EGF-related › Complement control module/SCR domain › Sushi | 0.55 | 12.0 | 2.33e-01 | 72.7% | 60.0% |
D3
high
residues 368-498