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tyrosine_kinase
Euk-VirPhascolarctid_gammaherpesvirus_1
tyrosine_kinase__YP_010087478__Phascolarctid_gammaherpesvirus_1__2249313
Identity
- Accession:
- YP_010087478 ↗
- Protein ID:
- tyrosine_kinase
- Kingdom:
- euk
Quality
85.7
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Manticavirus›
Phascolarctid_gammaherpesvirus_1
TaxID: 2249313
Cluster
View cluster (78 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 43-155
Domain cluster:
rep: LacPavin_0818_WC40_scaffold_75050_prodigal-single.1__X__X__00028__D32-119
D2
medium
residues 177-201_259-338
Domain cluster:
representative
CATH (8)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3v5uA01 | 6.10.280.80 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NCX, peripheral helical region | 0.60 | 29.0 | 3.35e-01 | 81.0% | 63.2% |
| 3terA00 | 1.10.287.3550 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.59 | 34.0 | 3.31e-01 | 84.8% | 50.4% |
| 1ic8A01 | 1.10.260.40 | Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains | 0.56 | 43.0 | 4.52e-01 | 82.9% | 91.5% |
| 1l8dA00 | 1.10.287.510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.55 | 32.0 | 3.30e-01 | 84.8% | 59.2% |
| 4it1B01 | 3.30.390.10 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain | 0.55 | 39.0 | 3.45e-01 | 100.0% | 51.0% |
| 1jq5A02 | 1.20.1090.10 | Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain | 0.54 | 38.0 | 3.11e-01 | 73.3% | 95.1% |
| 7lb8B01 | 1.10.3470.10 | Mainly Alpha › Orthogonal Bundle › ABC transporter involved in vitamin B12 uptake, BtuC › ABC transporter involved in vitamin B12 uptake, BtuC | 0.52 | 45.0 | 3.26e-01 | 99.0% | 47.3% |
| 3pvlA03 | 1.20.80.10 | Mainly Alpha › Up-down Bundle › Acyl-CoA Binding Protein › | 0.51 | 37.0 | 3.60e-01 | 76.2% | 100.0% |
ECOD (8)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3927014 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.58 | 34.0 | 2.99e-01 | 92.4% | 40.0% |
| 4979715 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.56 | 36.0 | 3.19e-01 | 71.4% | 44.7% |
| 3928106 | 632.7.1.25 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › PF27508 | 0.55 | 39.0 | 3.70e-01 | 72.4% | 84.2% |
| 3611880 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.55 | 43.0 | 3.32e-01 | 84.8% | 80.4% |
| 4267497 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.52 | 37.0 | 2.93e-01 | 71.4% | 60.1% |
| 4680153 | 7015.1.1.1 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › DHHC | 0.52 | 38.0 | 3.45e-01 | 76.2% | 74.3% |
| 3255565 | 2002.1.1.17 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › PEPcase | 0.52 | 41.0 | 2.43e-01 | 85.7% | 93.6% |
| 3164482 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.52 | 40.0 | 3.26e-01 | 82.9% | 54.2% |
D3
medium
residues 339-432
Domain cluster:
representative
CATH (15)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 7dwqL01 | 1.20.1240.10 | Mainly Alpha › Up-down Bundle › Photosystem 1 Reaction Centre Subunit Xi; Chain: L; › Photosystem I PsaL, reaction centre subunit XI | 0.65 | 46.0 | 4.22e-01 | 74.5% | 87.2% |
| 1jkwA01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.62 | 40.0 | 3.27e-01 | 73.4% | 34.7% |
| 3u9jA00 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.61 | 43.0 | 3.67e-01 | 74.5% | 96.8% |
| 2of3A00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.59 | 40.0 | 2.88e-01 | 70.2% | 62.8% |
| 1juqC00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.59 | 41.0 | 3.53e-01 | 74.5% | 45.6% |
| 3owaA01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.56 | 39.0 | 3.44e-01 | 71.3% | 50.0% |
| 6pnjL00 | 1.20.1240.10 | Mainly Alpha › Up-down Bundle › Photosystem 1 Reaction Centre Subunit Xi; Chain: L; › Photosystem I PsaL, reaction centre subunit XI | 0.56 | 41.0 | 3.50e-01 | 76.6% | 71.8% |
| 3ejbH02 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.56 | 49.0 | 3.53e-01 | 96.8% | 35.1% |
| 1dd5A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.53 | 38.0 | 3.70e-01 | 76.6% | 97.2% |
| 3whjA00 | 6.10.140.1710 | Special › Helix non-globular › Helix Hairpins › | 0.52 | 38.0 | 3.60e-01 | 74.5% | 82.0% |
| 1i6zA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.52 | 37.0 | 3.36e-01 | 74.5% | 77.0% |
| 2dr1A01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.52 | 36.0 | 3.18e-01 | 71.3% | 90.4% |
| 6o0aA01 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.51 | 37.0 | 3.26e-01 | 76.6% | 91.9% |
| 3ln6A01 | 3.30.590.20 | Alpha Beta › 2-Layer Sandwich › Creatine Kinase; Chain A, domain 2 › | 0.51 | 39.0 | 2.61e-01 | 83.0% | 49.4% |
| 4hehA01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.51 | 39.0 | 4.15e-01 | 98.9% | 94.0% |
ECOD (9)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4226297 | 7014.1.1.1 ↗ | alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › BacA | 0.71 | 60.0 | 5.44e-01 | 92.6% | 94.4% |
| 3699448 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.66 | 44.0 | 3.66e-01 | 74.5% | 38.8% |
| 3508723 | 6155.1.1.1 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MtN3_slv | 0.64 | 46.0 | 4.22e-01 | 75.5% | 61.6% |
| 3667321 | 621.1.1.12 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › SYS1 | 0.60 | 43.0 | 3.88e-01 | 74.5% | 60.8% |
| 4465759 | 150.3.1.2 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › Interferon | 0.55 | 48.0 | 3.93e-01 | 97.9% | 71.7% |
| 3726223 | 207.1.1.50 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_4,LRR_6 | 0.55 | 36.0 | 2.37e-01 | 80.9% | 16.5% |
| 3294636 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.53 | 41.0 | 3.88e-01 | 84.0% | 83.5% |
| 3278735 | 102.1.1.54 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › DNA_ligase_ZBD | 0.52 | 32.0 | 3.04e-01 | 83.0% | 52.2% |
| 4939889 | 547.1.1.1 ↗ | alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer | 0.51 | 34.0 | 3.23e-01 | 70.2% | 68.3% |