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ubiquitin-conjugating_enzyme_E2

Euk-Vir

Acanthamoeba_polyphaga_moumouvirus

ubiquitin-conjugating_enzyme_E2__YP_007354525__Acanthamoeba_polyphaga_moumouvirus__1269028

Identity

Accession:
YP_007354525 ↗
Protein ID:
ubiquitin-conjugating_enzyme_E2
Kingdom:
euk

Quality

43.5 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 13-107
PDB
D2 medium residues 715-803
PDB
D3 medium residues 987-1047
PDB
Domain cluster: representative
CATH (55)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1b04A03 1.10.287.610 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.87 65.0 6.52e-01 78.7% 79.0%
3r84A00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.78 62.0 5.63e-01 90.2% 65.4%
1luwA01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.77 63.0 6.26e-01 90.2% 92.2%
1ku9A02 1.10.287.450 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.77 63.0 6.26e-01 90.2% 87.5%
1hr5A00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.76 54.0 5.93e-01 75.4% 95.8%
1vq8V00 1.10.287.310 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.76 59.0 5.82e-01 93.4% 78.5%
4i0xG00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.76 61.0 5.94e-01 88.5% 94.1%
6r1nA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.75 63.0 5.28e-01 91.8% 55.3%
1gqeA01 1.20.58.410 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Release factor 0.75 64.0 5.14e-01 91.8% 73.5%
4e4eA01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.74 61.0 5.86e-01 91.8% 78.9%
1nt2B02 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.74 62.0 6.01e-01 91.8% 88.1%
2gd5A00 6.10.140.1230 Special › Helix non-globular › Helix Hairpins › 0.73 61.0 4.62e-01 91.8% 45.1%
3b2eF00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.73 56.0 5.58e-01 82.0% 88.7%
2ic6A00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 58.0 5.61e-01 96.7% 77.5%
1b3qA01 1.10.287.560 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Histidine kinase CheA-like, homodimeric domain 0.72 60.0 6.01e-01 100.0% 90.3%
4b6xA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 54.0 5.26e-01 91.8% 73.9%
1lvfB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.71 63.0 5.29e-01 100.0% 72.1%
2e9xA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.71 64.0 4.98e-01 100.0% 53.1%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.71 58.0 5.06e-01 90.2% 62.6%
1kfdA02 1.20.1060.10 Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 0.70 58.0 5.57e-01 100.0% 78.9%
1tjoB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.70 63.0 4.50e-01 100.0% 37.1%
5k3hB04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.70 57.0 4.32e-01 86.9% 39.8%
4abmD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.70 57.0 5.33e-01 91.8% 79.2%
2kp8A00 1.20.5.170 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.69 50.0 4.80e-01 77.0% 69.4%
1p49A02 1.10.287.550 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.69 55.0 5.58e-01 91.8% 89.8%
3lssA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.69 53.0 4.46e-01 90.2% 47.3%
2p4vA01 1.10.287.180 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain 0.69 60.0 5.60e-01 100.0% 82.9%
2bdeA03 1.20.58.1160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 56.0 5.21e-01 91.8% 72.7%
3l1nA01 6.10.140.790 Special › Helix non-globular › Helix Hairpins › 0.68 49.0 5.25e-01 88.5% 94.1%
4aflA00 6.10.140.1740 Special › Helix non-globular › Helix Hairpins › 0.67 55.0 4.70e-01 91.8% 61.8%
3agtA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.67 54.0 4.22e-01 88.5% 42.1%
8b6jF01 1.10.287.20 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Ubiquinol-cytochrome C reductase hinge domain 0.67 44.0 4.30e-01 70.5% 61.2%
1z0jB00 4.10.860.20 Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain 0.67 47.0 5.02e-01 78.7% 90.2%
2q12A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.67 53.0 3.62e-01 90.2% 30.6%
1wa8A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.67 57.0 4.89e-01 96.7% 71.7%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.67 54.0 4.54e-01 90.2% 53.8%
2a2cA03 1.20.1440.340 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.66 55.0 4.23e-01 93.4% 61.6%
6ynwH01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.65 48.0 4.57e-01 80.3% 68.9%
2etnB01 1.10.287.180 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain 0.65 55.0 5.21e-01 100.0% 84.2%
6tkvA01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.65 51.0 5.00e-01 95.1% 79.4%
4h63H01 1.20.58.1710 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 51.0 4.89e-01 91.8% 75.0%
3ay5A01 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.64 56.0 4.38e-01 98.4% 64.7%
1pd3A00 1.10.287.230 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.64 48.0 5.04e-01 91.8% 96.3%
4hz4A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.64 53.0 4.46e-01 100.0% 52.7%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.63 51.0 4.66e-01 91.8% 70.6%
3qavA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.63 49.0 3.89e-01 91.8% 39.3%
2x2vA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.61 48.0 4.67e-01 91.8% 77.9%
1ij5A01 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 49.0 4.64e-01 91.8% 73.7%
3unoE00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.60 52.0 3.87e-01 100.0% 57.5%
2kg7B00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.60 49.0 4.26e-01 91.8% 59.8%
2yv9B02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.60 51.0 4.06e-01 100.0% 51.5%
5fhiA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.60 50.0 3.92e-01 95.1% 73.4%
4q20A01 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.60 47.0 4.30e-01 88.5% 81.7%
2gtaA00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.59 50.0 4.40e-01 100.0% 67.0%
2xokP00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.57 47.0 4.48e-01 95.1% 79.7%
ECOD (54)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3625492 11.1.1.2 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › fn3 0.81 54.0 4.00e-01 75.4% 29.0%
4934026 192.4.1.1 alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) › Ribosomal_L29 0.79 62.0 6.09e-01 95.1% 78.5%
4201121 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.79 60.0 6.08e-01 91.8% 83.3%
3730904 650.1.1.14 alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › Med10 0.77 56.0 4.86e-01 82.0% 52.2%
3200160 604.7.1.0 alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A 0.76 61.0 5.02e-01 91.8% 49.1%
3484074 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.75 62.0 4.71e-01 90.2% 44.3%
4445940 192.4.1.1 alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) › Ribosomal_L29 0.75 58.0 5.47e-01 93.4% 69.9%
5029994 192.4.1.1 alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) › Ribosomal_L29 0.75 58.0 5.71e-01 93.4% 78.5%
3259118 3560.1.1.7 a+b complex topology › Mediator of RNA polymerase II transcription subunit 8 › Mediator of RNA polymerase II transcription subunit 8 › Mediator of RNA polymerase II transcription subunit 8 › Med10 0.75 59.0 4.67e-01 90.2% 43.3%
4401282 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.74 60.0 4.81e-01 91.8% 46.1%
4860885 633.6.1.6 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACAD9-ACADV_C 0.74 57.0 4.79e-01 83.6% 58.1%
3608116 5086.1.1.177 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › KIF9 0.74 61.0 4.64e-01 91.8% 46.9%
4961031 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.74 66.0 6.30e-01 100.0% 87.1%
3599499 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.74 61.0 4.58e-01 91.8% 37.3%
3553813 3291.1.1.82 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › ING 0.74 61.0 4.82e-01 91.8% 48.8%
3772767 5086.1.1.87 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING 0.73 61.0 4.81e-01 91.8% 48.8%
4038778 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.73 60.0 4.87e-01 90.2% 66.1%
3595108 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.73 66.0 5.78e-01 100.0% 72.2%
3663990 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.73 63.0 6.02e-01 95.1% 81.4%
3211184 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.73 62.0 5.49e-01 95.1% 66.7%
3448091 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.71 58.0 4.78e-01 91.8% 50.0%
3408094 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.71 63.0 4.86e-01 100.0% 65.2%
5038046 3896.1.1.0 alpha duplicates or obligate multimers › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase 0.71 60.0 4.24e-01 95.1% 32.6%
3412574 3291.1.1.82 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › ING 0.71 58.0 4.57e-01 91.8% 48.5%
3556027 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.71 58.0 5.24e-01 91.8% 68.2%
3855461 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.70 58.0 5.22e-01 91.8% 68.2%
3284621 150.5.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100 0.70 58.0 5.24e-01 91.8% 71.8%
3582396 109.4.1.1302 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF30363 0.70 62.0 4.31e-01 100.0% 32.0%
3302552 192.15.1.0 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains 0.70 54.0 4.17e-01 95.1% 37.1%
4257759 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.70 59.0 5.25e-01 100.0% 65.6%
3998454 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.70 55.0 4.81e-01 88.5% 69.5%
4465072 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.70 57.0 4.66e-01 91.8% 51.3%
3491418 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.70 58.0 5.41e-01 91.8% 76.0%
3354385 3755.1.1.22 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › DUF3475 0.69 59.0 4.09e-01 95.1% 28.3%
3933170 605.4.1.0 alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein 0.69 55.0 4.70e-01 91.8% 53.0%
4174713 192.1.1.2 alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain › GreA_GreB_N 0.69 59.0 5.50e-01 98.4% 78.8%
3864955 633.22.1.6 alpha bundles › Bromodomain-like › Vitamin K epoxide reductase (VKOR) › Vitamin K epoxide reductase (VKOR) › TMD0_ABC 0.69 60.0 4.39e-01 100.0% 67.6%
3507431 11.2.1.7 beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › Anillin 0.69 55.0 3.75e-01 90.2% 25.8%
5083225 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.69 53.0 5.25e-01 93.4% 80.0%
3731006 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.69 62.0 5.32e-01 100.0% 69.5%
4024927 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.68 55.0 5.15e-01 88.5% 73.3%
4977923 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.68 56.0 4.13e-01 91.8% 35.6%
3488333 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.67 59.0 4.82e-01 100.0% 76.5%
4055485 192.4.1.1 alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) › Ribosomal_L29 0.67 54.0 5.15e-01 93.4% 75.7%
4947573 3755.1.1.0 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related 0.66 53.0 3.41e-01 90.2% 18.0%
5047384 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.66 54.0 5.37e-01 91.8% 86.2%
3285409 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.66 53.0 3.82e-01 90.2% 31.9%
3473545 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.66 59.0 4.44e-01 100.0% 83.1%
4110261 3748.1.1.2 extended segments › 26S proteasome regulatory subunit RPN8/RPN11 C-terminal domain › 26S proteasome regulatory subunit RPN8/RPN11 C-terminal domain › 26S proteasome regulatory subunit RPN8/RPN11 C-terminal domain › CSN5_C 0.66 57.0 5.10e-01 96.7% 70.6%
3752758 3755.3.1.467 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DRC7_C 0.66 52.0 3.99e-01 90.2% 36.9%
3385950 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.66 54.0 5.28e-01 96.7% 87.1%
4243427 3560.1.1.1 a+b complex topology › Mediator of RNA polymerase II transcription subunit 8 › Mediator of RNA polymerase II transcription subunit 8 › Mediator of RNA polymerase II transcription subunit 8 › Med8 0.65 50.0 3.78e-01 90.2% 32.5%
3798984 3560.1.1.0 a+b complex topology › Mediator of RNA polymerase II transcription subunit 8 › Mediator of RNA polymerase II transcription subunit 8 › Mediator of RNA polymerase II transcription subunit 8 0.62 50.0 3.60e-01 95.1% 28.7%
3708688 650.1.1.1 alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ 0.62 46.0 4.15e-01 80.3% 58.8%
D4 medium residues 1048-1113
PDB
D5 medium residues 1241-1338
PDB
Domain cluster: representative
CATH (38)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3cegA00 3.10.110.10 Alpha Beta › Roll › Ubiquitin Conjugating Enzyme › Ubiquitin Conjugating Enzyme 0.93 89.0 6.09e-01 100.0% 36.0%
2ra1A03 1.20.58.770 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 49.0 5.95e-01 76.5% 100.0%
1uurA01 1.20.58.240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 0.73 54.0 5.21e-01 77.6% 90.9%
1t72A01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.70 56.0 5.33e-01 85.7% 88.0%
1owaA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 58.0 5.67e-01 88.8% 99.1%
2jbwA01 1.20.1440.110 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase 0.70 52.0 5.18e-01 100.0% 74.8%
1wrdA00 1.20.58.160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 54.0 5.43e-01 83.7% 89.8%
2w02B01 1.10.150.640 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › AcsD, thumb domain, helical bundle 0.67 34.0 3.85e-01 78.6% 63.5%
3nvoB02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.66 56.0 5.28e-01 91.8% 92.2%
7wu8B01 1.20.1160.20 Mainly Alpha › Up-down Bundle › Paired amphipathic helix 2 (pah2 repeat) › 0.65 38.0 4.22e-01 92.9% 72.2%
2pftA00 1.20.1280.170 Mainly Alpha › Up-down Bundle › Monooxygenase › Exocyst complex component Exo70 0.65 54.0 3.45e-01 92.9% 46.2%
1s35A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 50.0 5.02e-01 83.7% 100.0%
1wcrA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.64 50.0 4.98e-01 84.7% 93.2%
1o5hA00 1.20.120.680 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle 0.64 57.0 4.53e-01 100.0% 86.5%
1sziA02 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.63 50.0 4.49e-01 85.7% 68.6%
2chpA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.62 46.0 4.11e-01 80.6% 95.3%
1j1jA01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.61 46.0 4.22e-01 80.6% 66.7%
4etrB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.61 47.0 4.42e-01 84.7% 99.2%
1st6A04 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.60 42.0 3.95e-01 77.6% 59.8%
3purA03 1.20.58.1360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 54.0 5.24e-01 100.0% 98.2%
3a7mA01 1.20.58.380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. 0.59 44.0 4.30e-01 78.6% 70.9%
4qndA00 1.20.1280.290 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.58 48.0 4.82e-01 90.8% 91.8%
8hk0B03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.58 44.0 3.96e-01 80.6% 89.9%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.58 40.0 3.89e-01 71.4% 68.2%
3l1nA02 1.20.1280.140 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.58 47.0 4.90e-01 93.9% 100.0%
3axjB01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.56 43.0 3.80e-01 84.7% 60.6%
4hyjA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.56 43.0 3.24e-01 81.6% 41.1%
6tkyA03 1.20.58.740 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › DOCK DHR2 domain, lobe C 0.56 50.0 4.63e-01 98.0% 84.4%
3zheA02 1.25.40.760 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.56 50.0 3.94e-01 100.0% 62.8%
4g12A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.56 45.0 3.95e-01 88.8% 93.3%
3on3B00 3.40.920.10 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate-ferredoxin Oxidoreductase; domain 3 › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 0.55 39.0 3.31e-01 74.5% 92.0%
1w0bA01 1.20.58.420 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP 0.53 40.0 4.15e-01 82.7% 94.6%
3vprA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 41.0 3.62e-01 83.7% 58.6%
2qupA00 1.20.120.490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain 0.52 40.0 3.84e-01 85.7% 73.9%
1qdbA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.52 38.0 3.38e-01 76.5% 81.1%
3anwB00 1.20.58.2050 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 45.0 3.89e-01 100.0% 65.4%
4wqoD00 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.51 44.0 3.96e-01 96.9% 91.5%
2x1lA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.51 41.0 3.36e-01 85.7% 76.2%
ECOD (60)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3659245 216.1.1.0 a+b two layers › UBC-like › UBC-like › UBC-like 0.92 88.0 6.70e-01 100.0% 58.5%
3940734 216.1.1.1 a+b two layers › UBC-like › UBC-like › UBC-like › UQ_con 0.91 87.0 5.82e-01 100.0% 37.2%
3628012 216.1.1.1 a+b two layers › UBC-like › UBC-like › UBC-like › UQ_con 0.89 84.0 5.71e-01 100.0% 38.4%
3528863 604.6.1.1 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.77 59.0 5.64e-01 81.6% 76.5%
4466203 192.7.1.3 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Phe_tRNA-synt_N 0.72 49.0 5.29e-01 70.4% 85.9%
3940791 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.71 55.0 5.47e-01 80.6% 100.0%
3465357 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.71 54.0 5.13e-01 80.6% 83.5%
3808 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.70 55.0 5.39e-01 83.7% 97.2%
3224585 603.1.1.99 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27021 0.70 52.0 5.00e-01 77.6% 81.8%
4309318 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.70 54.0 5.30e-01 81.6% 87.6%
3583102 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.69 54.0 5.84e-01 83.7% 100.0%
4999454 604.10.1.0 alpha bundles › Spectrin repeat-like › Enzyme IIa from lactose specific PTS, IIa-lac › Enzyme IIa from lactose specific PTS, IIa-lac 0.69 54.0 5.37e-01 84.7% 93.3%
3815026 604.1.1.148 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › TBCC_N 0.69 53.0 5.61e-01 81.6% 100.0%
3442429 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.68 54.0 4.36e-01 84.7% 54.1%
3307044 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.68 52.0 5.08e-01 80.6% 83.8%
3528346 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.68 57.0 4.77e-01 90.8% 65.5%
3641813 604.6.1.1 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.68 56.0 5.71e-01 100.0% 90.5%
4102807 192.7.1.3 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Phe_tRNA-synt_N 0.67 48.0 4.74e-01 74.5% 71.4%
4200387 192.7.1.3 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Phe_tRNA-synt_N 0.67 47.0 4.93e-01 72.4% 83.3%
4646625 192.7.1.3 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Phe_tRNA-synt_N 0.67 47.0 4.69e-01 72.4% 74.0%
3935032 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.67 52.0 5.13e-01 83.7% 99.0%
5063996 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.66 58.0 4.47e-01 98.0% 94.7%
3509024 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.66 52.0 5.13e-01 84.7% 85.7%
3619641 604.1.1.154 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF27021 0.66 47.0 4.61e-01 73.5% 79.0%
4199922 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.66 59.0 5.39e-01 99.0% 100.0%
4284928 314.1.1.0 a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases 0.66 46.0 3.14e-01 72.4% 21.4%
1868087 622.1.1.2 alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain › HsbA 0.66 47.0 4.99e-01 75.5% 94.2%
4056592 622.1.1.2 alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain › HsbA 0.66 52.0 4.42e-01 85.7% 90.3%
3580280 604.1.1.192 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF26998 0.66 53.0 5.39e-01 85.7% 97.9%
2055366 622.1.1.2 alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain › HsbA 0.66 48.0 5.10e-01 76.5% 100.0%
3626530 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.66 52.0 5.33e-01 87.8% 100.0%
3919843 604.1.1.124 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_6 0.65 53.0 4.87e-01 88.8% 94.6%
3425962 603.1.1.116 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27980 0.64 49.0 5.20e-01 80.6% 98.8%
4931503 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.64 46.0 5.09e-01 75.5% 97.3%
3252898 109.4.1.1 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › 14-3-3 0.64 51.0 3.95e-01 88.8% 49.8%
4251267 192.7.1.3 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Phe_tRNA-synt_N 0.64 47.0 4.60e-01 76.5% 73.3%
3318287 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.63 49.0 4.03e-01 82.7% 50.6%
3484774 622.1.1.1 alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain › HSCB_C 0.63 47.0 4.67e-01 80.6% 90.5%
4998480 109.4.1.207 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_2 0.63 54.0 3.16e-01 95.9% 19.3%
3660443 604.6.1.40 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › PF27980 0.63 49.0 5.09e-01 83.7% 97.8%
3783044 6155.1.1.2 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop 0.62 50.0 5.16e-01 88.8% 94.4%
4987854 109.3.1.487 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › DUF5667 0.62 55.0 4.94e-01 100.0% 97.9%
3239393 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.62 48.0 4.67e-01 100.0% 74.5%
3506950 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.61 47.0 4.93e-01 83.7% 100.0%
3591396 3866.1.1.0 extended segments › Mitochondrial 54S ribosomal protein L25 › Mitochondrial 54S ribosomal protein L25 › Mitochondrial 54S ribosomal protein L25 0.61 48.0 4.86e-01 83.7% 93.7%
3701375 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.61 47.0 4.84e-01 83.7% 93.7%
3252200 603.1.1.6 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin_2 0.61 54.0 4.63e-01 100.0% 81.9%
3439705 3758.1.1.7 alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins › BPS1 0.61 53.0 4.16e-01 100.0% 96.8%
3936693 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.60 45.0 4.50e-01 78.6% 90.0%
3453407 109.4.1.359 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Exo70_C 0.60 52.0 3.44e-01 100.0% 42.2%
3810544 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.60 52.0 4.70e-01 98.0% 92.6%
3301847 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.59 46.0 4.63e-01 85.7% 95.0%
3375952 6155.1.1.1 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MtN3_slv 0.57 47.0 4.10e-01 89.8% 76.7%
4982605 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.57 43.0 4.04e-01 81.6% 78.0%
3545594 109.4.1.256 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Insc_C 0.55 41.0 4.01e-01 81.6% 72.7%
3187659 622.1.1.2 alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain › HsbA 0.54 49.0 4.18e-01 100.0% 62.6%
3773131 109.4.1.342 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SBF2 0.54 49.0 3.59e-01 100.0% 39.6%
3964012 3831.1.1.1 alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › LprI 0.54 43.0 4.14e-01 84.7% 82.7%
3286299 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.53 37.0 3.65e-01 73.5% 77.3%
3544351 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.52 45.0 3.05e-01 98.0% 42.7%