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ubiquitin_E3_ligase_ICP0
Euk-VirEquid_alphaherpesvirus_9
ubiquitin_E3_ligase_ICP0__YP_002333544__Equid_alphaherpesvirus_9__55744
Identity
- Accession:
- YP_002333544 ↗
- Protein ID:
- ubiquitin_E3_ligase_ICP0
- Kingdom:
- euk
Quality
48.0
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Varicellovirus›
Equid_alphaherpesvirus_9
TaxID: 55744
Cluster
View cluster (5 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 120-192
Domain cluster:
representative
CATH (28)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4dxwA02 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.66 | 57.0 | 5.01e-01 | 100.0% | 71.4% |
| 1c3cA03 | 1.10.40.30 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase Protein R1; domain 1 › Fumarase/aspartase (C-terminal domain) | 0.65 | 51.0 | 4.96e-01 | 93.2% | 77.8% |
| 6e1kA01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.65 | 57.0 | 5.00e-01 | 100.0% | 71.4% |
| 1tj7A03 | 1.10.40.30 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase Protein R1; domain 1 › Fumarase/aspartase (C-terminal domain) | 0.65 | 52.0 | 5.25e-01 | 97.3% | 93.0% |
| 1dcnA03 | 1.10.40.30 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase Protein R1; domain 1 › Fumarase/aspartase (C-terminal domain) | 0.64 | 53.0 | 5.36e-01 | 95.9% | 95.8% |
| 3s63A00 | 1.10.225.10 | Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like | 0.63 | 46.0 | 4.36e-01 | 78.1% | 75.0% |
| 4h8aB01 | 1.10.1530.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 › Malate/L-lactate/L-sulpholactate dehydrogenase, four-helix barrel | 0.62 | 43.0 | 4.68e-01 | 76.7% | 88.3% |
| 2xzmV01 | 1.10.60.20 | Mainly Alpha › Orthogonal Bundle › Diphtheria Toxin Repressor; domain 2 › Ribosomal protein S17 | 0.62 | 44.0 | 4.69e-01 | 84.9% | 90.2% |
| 2g8lB01 | 1.10.8.380 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Uncharacterised protein PF01937, DUF89, domain 1 | 0.62 | 44.0 | 4.59e-01 | 76.7% | 95.5% |
| 4tq1A03 | 1.10.246.190 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › Autophagy protein Apg5, helix rich domain | 0.61 | 42.0 | 4.60e-01 | 74.0% | 96.6% |
| 6tmfT00 | 1.10.60.20 | Mainly Alpha › Orthogonal Bundle › Diphtheria Toxin Repressor; domain 2 › Ribosomal protein S17 | 0.60 | 45.0 | 4.72e-01 | 83.6% | 92.2% |
| 3fvvA02 | 1.20.1440.100 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › SG protein - dephosphorylation function | 0.59 | 41.0 | 4.12e-01 | 86.3% | 70.7% |
| 3x0uB01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.59 | 45.0 | 3.25e-01 | 86.3% | 40.7% |
| 2b6cA01 | 1.20.1660.10 | Mainly Alpha › Up-down Bundle › ARM repeat fold › Hypothetical protein (EF3068) | 0.57 | 41.0 | 3.58e-01 | 78.1% | 76.7% |
| 7jveC01 | 3.40.30.10 | Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin | 0.56 | 48.0 | 3.41e-01 | 98.6% | 64.5% |
| 3dyjA02 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.56 | 40.0 | 3.23e-01 | 76.7% | 88.1% |
| 2kjgA00 | 1.20.120.970 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.56 | 47.0 | 4.30e-01 | 97.3% | 78.8% |
| 4nleA03 | 1.10.40.30 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase Protein R1; domain 1 › Fumarase/aspartase (C-terminal domain) | 0.56 | 46.0 | 4.64e-01 | 98.6% | 98.7% |
| 4akgA06 | 1.10.8.710 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Dynein motor, AAA1 domain, small subdomain | 0.55 | 46.0 | 4.12e-01 | 94.5% | 75.7% |
| 1mjtB01 | 3.90.340.10 | Alpha Beta › Alpha-Beta Complex › Nitric Oxide Synthase; Chain A, domain 1 › Nitric Oxide Synthase; Chain A, domain 1 | 0.55 | 44.0 | 3.75e-01 | 90.4% | 75.2% |
| 3l1nA02 | 1.20.1280.140 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.54 | 38.0 | 3.60e-01 | 74.0% | 96.6% |
| 3zciA00 | 1.20.58.1660 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 45.0 | 3.43e-01 | 100.0% | 88.0% |
| 4zqeA03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.53 | 37.0 | 3.45e-01 | 74.0% | 83.3% |
| 3ma5A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.53 | 36.0 | 3.43e-01 | 72.6% | 92.2% |
| 1sj8A02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.52 | 44.0 | 3.83e-01 | 100.0% | 91.0% |
| 4w8pA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.52 | 38.0 | 3.15e-01 | 76.7% | 82.3% |
| 7p2yC03 | 1.20.150.20 | Mainly Alpha › Up-down Bundle › Lysin › ATP synthase alpha/beta chain, C-terminal domain | 0.51 | 41.0 | 3.44e-01 | 90.4% | 51.2% |
| 1bgfA00 | 1.10.532.10 | Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain | 0.50 | 42.0 | 3.65e-01 | 100.0% | 91.1% |
ECOD (31)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3272359 | 592.1.1.1 ↗ | alpha arrays › PWI domain-like › PWI domain › PWI domain › PWI | 0.90 | 82.0 | 7.11e-01 | 100.0% | 67.6% |
| 4026102 | 592.1.1.1 ↗ | alpha arrays › PWI domain-like › PWI domain › PWI domain › PWI | 0.85 | 78.0 | 7.74e-01 | 100.0% | 96.0% |
| 4078112 | 592.1.1.1 ↗ | alpha arrays › PWI domain-like › PWI domain › PWI domain › PWI | 0.85 | 77.0 | 7.48e-01 | 100.0% | 91.1% |
| 4027661 | 592.1.1.1 ↗ | alpha arrays › PWI domain-like › PWI domain › PWI domain › PWI | 0.85 | 77.0 | 6.46e-01 | 100.0% | 62.5% |
| 3390973 | 592.1.1.1 ↗ | alpha arrays › PWI domain-like › PWI domain › PWI domain › PWI | 0.84 | 75.0 | 6.35e-01 | 100.0% | 61.7% |
| 3789516 | 592.1.1.1 ↗ | alpha arrays › PWI domain-like › PWI domain › PWI domain › PWI | 0.83 | 75.0 | 7.30e-01 | 100.0% | 91.1% |
| 3807088 | 592.1.1.6 ↗ | alpha arrays › PWI domain-like › PWI domain › PWI domain › Nab2 | 0.83 | 73.0 | 7.44e-01 | 98.6% | 98.6% |
| 3661711 | 592.1.1.1 ↗ | alpha arrays › PWI domain-like › PWI domain › PWI domain › PWI | 0.82 | 74.0 | 7.22e-01 | 100.0% | 88.7% |
| 3623929 | 592.1.1.5 ↗ | alpha arrays › PWI domain-like › PWI domain › PWI domain › PF26084 | 0.82 | 74.0 | 6.89e-01 | 98.6% | 84.4% |
| 3798777 | 592.1.1.0 ↗ | alpha arrays › PWI domain-like › PWI domain › PWI domain | 0.82 | 73.0 | 7.46e-01 | 97.3% | 100.0% |
| 3193662 | 592.1.1.1 ↗ | alpha arrays › PWI domain-like › PWI domain › PWI domain › PWI | 0.81 | 73.0 | 7.12e-01 | 97.3% | 98.8% |
| 3413518 | 592.1.1.7 ↗ | alpha arrays › PWI domain-like › PWI domain › PWI domain › PF26091 | 0.80 | 74.0 | 7.36e-01 | 100.0% | 97.3% |
| 3403783 | 592.1.1.0 ↗ | alpha arrays › PWI domain-like › PWI domain › PWI domain | 0.79 | 71.0 | 5.88e-01 | 100.0% | 57.8% |
| 3480380 | 592.1.1.0 ↗ | alpha arrays › PWI domain-like › PWI domain › PWI domain | 0.77 | 69.0 | 5.99e-01 | 98.6% | 90.9% |
| 3510833 | 592.1.1.2 ↗ | alpha arrays › PWI domain-like › PWI domain › PWI domain › Helicase_PWI | 0.76 | 69.0 | 5.71e-01 | 98.6% | 80.0% |
| 4122290 | 191.1.1.0 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain | 0.75 | 53.0 | 4.63e-01 | 74.0% | 67.6% |
| 2492230 | 142.1.1.3 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 | 0.73 | 52.0 | 4.48e-01 | 74.0% | 60.0% |
| 3528955 | 103.4.1.6 ↗ | alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › EloA-BP1 | 0.68 | 48.0 | 5.23e-01 | 89.0% | 90.0% |
| 3335568 | 160.1.1.1 ↗ | alpha superhelices › C-terminal domain of alpha and beta subunits of F1 ATP synthase › C-terminal domain of alpha and beta subunits of F1 ATP synthase › C-terminal domain of alpha and beta subunits of F1 ATP synthase › ATP-synt_ab_C | 0.63 | 44.0 | 4.02e-01 | 74.0% | 74.0% |
| 3614 | 4009.1.1.1 ↗ | alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › ARMT1-like_dom | 0.59 | 45.0 | 4.58e-01 | 82.2% | 94.3% |
| 5071361 | 4009.1.1.0 ↗ | alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins | 0.58 | 44.0 | 4.41e-01 | 82.2% | 94.7% |
| 3516166 | 1128.1.1.1 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR | 0.55 | 38.0 | 3.57e-01 | 87.7% | 56.8% |
| 3711066 | 4156.1.1.4 ↗ | alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › HA2_C | 0.55 | 47.0 | 3.72e-01 | 100.0% | 72.1% |
| 3970178 | 5060.2.1.0 ↗ | alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain | 0.55 | 44.0 | 3.71e-01 | 95.9% | 49.0% |
| 3961347 | 150.5.1.53 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › PPE | 0.54 | 35.0 | 3.39e-01 | 100.0% | 57.6% |
| 3928739 | 611.8.1.0 ↗ | alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 | 0.53 | 41.0 | 3.54e-01 | 84.9% | 65.3% |
| 4119718 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.52 | 38.0 | 3.56e-01 | 76.7% | 86.7% |
| 3721324 | 633.21.1.25 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › DUF7598 | 0.52 | 44.0 | 3.66e-01 | 98.6% | 82.8% |
| 3441997 | 103.1.1.0 ↗ | alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain | 0.51 | 41.0 | 3.89e-01 | 94.5% | 81.1% |
| 5043090 | 5058.1.1.16 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 | 0.51 | 37.0 | 3.65e-01 | 78.1% | 86.3% |
| 3316949 | 4006.1.1.0 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain | 0.50 | 39.0 | 3.24e-01 | 86.3% | 86.7% |
D2
medium
residues 1-61_97-112