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ubiquitin_E3_ligase_ICP0
Euk-VirCanid_alphaherpesvirus_1
ubiquitin_E3_ligase_ICP0__YP_009252287__Canid_alphaherpesvirus_1__170325
Identity
- Accession:
- YP_009252287 ↗
- Protein ID:
- ubiquitin_E3_ligase_ICP0
- Kingdom:
- euk
Quality
57.5
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Varicellovirus›
Canid_alphaherpesvirus_1
TaxID: 170325
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 18-67
Domain cluster:
rep: ubiquitin_E3_ligase_ICP0__YP_068377__Suid_alphaherpesvirus_1__10345__D13-62
Pfam (4)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF13920.13 best | zf-C3HC4_3 | 29.0 | 1.10e-06 | 72.0% | 71.4% |
| PF13639.13 | zf-RING_2 | 35.2 | 1.60e-08 | 60.0% | 63.6% |
| PF13923.13 | zf-C3HC4_2 | 29.5 | 7.00e-07 | 58.0% | 67.5% |
| PF00097.32 | zf-C3HC4 | 32.3 | 9.80e-08 | 58.0% | 67.5% |
D2
medium
residues 134-216_277-301
Domain cluster:
representative
CATH (15)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3lcnB00 | 1.10.340.40 | Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › Nuclear abundant poly(A) RNA-bind protein 2, N-terminal domain | 0.79 | 54.0 | 5.73e-01 | 70.4% | 81.4% |
| 1dcnA03 | 1.10.40.30 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase Protein R1; domain 1 › Fumarase/aspartase (C-terminal domain) | 0.73 | 45.0 | 5.40e-01 | 70.4% | 93.1% |
| 2gfhA02 | 1.20.120.710 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Haloacid dehalogenase hydrolase-like domain | 0.69 | 48.0 | 5.31e-01 | 72.2% | 100.0% |
| 3ddhA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.67 | 46.0 | 5.16e-01 | 70.4% | 100.0% |
| 4h8aB01 | 1.10.1530.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 › Malate/L-lactate/L-sulpholactate dehydrogenase, four-helix barrel | 0.64 | 36.0 | 4.62e-01 | 97.2% | 100.0% |
| 6zhiB02 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.59 | 33.0 | 3.70e-01 | 84.3% | 69.9% |
| 6d2qA02 | 1.20.80.10 | Mainly Alpha › Up-down Bundle › Acyl-CoA Binding Protein › | 0.57 | 31.0 | 3.18e-01 | 97.2% | 51.9% |
| 4lwsA00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.55 | 28.0 | 2.99e-01 | 71.3% | 54.0% |
| 1e9rA02 | 1.10.8.80 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Magnesium chelatase subunit I, C-Terminal domain | 0.55 | 45.0 | 4.49e-01 | 100.0% | 85.0% |
| 1c9bA02 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.55 | 45.0 | 4.58e-01 | 90.7% | 93.4% |
| 3kp1E02 | 1.10.8.1000 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ornithine 4,5 aminomutase S component, alpha subunit-like | 0.54 | 32.0 | 3.86e-01 | 83.3% | 90.0% |
| 3djbA01 | 1.10.472.50 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › HD-domain/PDEase-like | 0.54 | 41.0 | 4.28e-01 | 79.6% | 100.0% |
| 4hr1A00 | 1.20.1270.410 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.53 | 37.0 | 3.69e-01 | 75.0% | 95.8% |
| 2cfqA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.52 | 37.0 | 3.04e-01 | 73.1% | 79.5% |
| 2dlaA01 | 1.20.930.50 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › | 0.51 | 37.0 | 3.27e-01 | 75.9% | 86.3% |
ECOD (8)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4026102 | 592.1.1.1 ↗ | alpha arrays › PWI domain-like › PWI domain › PWI domain › PWI | 0.83 | 57.0 | 6.74e-01 | 70.4% | 100.0% |
| 4990384 | 3896.1.2.0 ↗ | alpha duplicates or obligate multimers › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-archaeol synthase | 0.65 | 44.0 | 3.90e-01 | 98.1% | 49.0% |
| 3593055 | 3542.1.1.0 ↗ | alpha arrays › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases | 0.58 | 41.0 | 3.12e-01 | 72.2% | 53.8% |
| 3494149 | 601.1.2.6 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_IBS2B | 0.55 | 38.0 | 3.40e-01 | 71.3% | 74.5% |
| 4938848 | 5069.1.3.131 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › DUF92 | 0.54 | 40.0 | 4.14e-01 | 99.1% | 84.0% |
| 3596906 | 606.1.1.0 ↗ | alpha complex topology › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain | 0.54 | 42.0 | 4.03e-01 | 90.7% | 70.8% |
| 3951208 | 3352.1.1.0 ↗ | alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain | 0.51 | 44.0 | 2.94e-01 | 93.5% | 84.7% |
| 5000678 | 101.1.10.0 ↗ | alpha arrays › HTH › HTH › Cyclin-like | 0.51 | 42.0 | 4.40e-01 | 94.4% | 100.0% |