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uncharacterized_Bro-N_domain-containing_protein

Euk-Vir

Acanthamoeba_polyphaga_mimivirus

uncharacterized_Bro-N_domain-containing_protein__YP_003986476__Acanthamoeba_polyphaga_mimivirus__212035

Identity

Accession:
YP_003986476 ↗
Protein ID:
uncharacterized_Bro-N_domain-containing_protein
Kingdom:
euk

Quality

74.4 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Megaviricetes› Imitervirales› Mimiviridae› Mimivirus› Acanthamoeba_polyphaga_mimivirus

TaxID: 212035

Cluster

View cluster (6 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 1-82
PDB
Domain cluster: representative
CATH (30)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1l8rA00 3.10.260.20 Alpha Beta › Roll › Mlu1-box Binding Protein; DNA-binding Domain › Ski 0.71 58.0 5.38e-01 86.6% 90.1%
1sbxA00 3.10.260.20 Alpha Beta › Roll › Mlu1-box Binding Protein; DNA-binding Domain › Ski 0.68 56.0 5.09e-01 87.8% 85.8%
2xfvA00 3.10.260.30 Alpha Beta › Roll › Mlu1-box Binding Protein; DNA-binding Domain › 0.66 55.0 5.01e-01 90.2% 90.7%
4r24B00 1.10.1660.10 Mainly Alpha › Orthogonal Bundle › Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 › 0.64 46.0 4.59e-01 89.0% 72.9%
1wfxA01 1.10.10.970 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › RNA 2'-phosphotransferase, Tpt1/KptA family, N-terminal domain 0.60 41.0 4.28e-01 70.7% 90.1%
4fz2A01 3.40.1170.20 Alpha Beta › 3-Layer(aba) Sandwich › MutS, DNA mismatch repair protein, domain I › tRNA intron endonuclease, N-terminal domain 0.60 44.0 4.55e-01 90.2% 85.3%
2kbiA01 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.59 49.0 4.96e-01 92.7% 94.9%
3i6dB03 1.10.3110.10 Mainly Alpha › Orthogonal Bundle › protoporphyrinogen ix oxidase, domain 3 › protoporphyrinogen ix oxidase, domain 3 0.59 37.0 3.97e-01 96.3% 76.1%
1wy9A00 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.59 48.0 4.44e-01 98.8% 68.5%
6e3aA01 1.10.10.970 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › RNA 2'-phosphotransferase, Tpt1/KptA family, N-terminal domain 0.59 41.0 4.23e-01 73.2% 89.5%
1a79A02 3.40.1170.20 Alpha Beta › 3-Layer(aba) Sandwich › MutS, DNA mismatch repair protein, domain I › tRNA intron endonuclease, N-terminal domain 0.58 42.0 4.50e-01 90.2% 90.1%
3mq0A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.57 36.0 3.73e-01 80.5% 66.2%
7kw8A01 1.10.10.970 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › RNA 2'-phosphotransferase, Tpt1/KptA family, N-terminal domain 0.57 40.0 4.18e-01 73.2% 93.2%
1sseB00 1.10.238.100 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › YAP1 redox domain. Chain B 0.56 39.0 3.89e-01 87.8% 69.8%
4b0zA00 1.25.40.990 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.55 32.0 2.40e-01 72.0% 20.3%
3nksA00 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.54 41.0 2.62e-01 92.7% 14.6%
2l02A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 37.0 3.76e-01 96.3% 72.0%
3cuoD00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 38.0 3.71e-01 95.1% 66.0%
1mkmB01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 34.0 3.49e-01 78.0% 68.4%
4hw0C00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 40.0 3.88e-01 84.1% 73.1%
2ku7A00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.52 40.0 3.43e-01 85.4% 77.1%
2obpA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 40.0 4.04e-01 96.3% 84.0%
2qlzA03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 31.0 3.36e-01 70.7% 74.6%
4asnA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 39.0 3.82e-01 93.9% 75.6%
4bpxD00 1.20.930.80 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › 0.51 41.0 3.04e-01 89.0% 33.3%
3t5vA00 1.25.40.990 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.51 39.0 2.70e-01 87.8% 22.7%
2bgcA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 42.0 3.98e-01 95.1% 76.2%
3qx3B03 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.51 36.0 3.47e-01 76.8% 80.0%
3m8eA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 41.0 3.84e-01 89.0% 70.3%
1rz4A02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 34.0 3.34e-01 98.8% 62.0%
ECOD (44)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4176315 101.1.9.16 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain › HTH_17 0.74 48.0 5.65e-01 79.3% 100.0%
3953197 101.1.9.16 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain › HTH_17 0.73 47.0 4.50e-01 85.4% 56.8%
4527613 101.1.9.16 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain › HTH_17 0.72 47.0 4.82e-01 80.5% 69.6%
3284686 101.1.9.84 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain › MerR, MerR_1 0.71 51.0 3.63e-01 89.0% 26.5%
4548007 101.1.9.16 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain › HTH_17 0.71 49.0 4.89e-01 72.0% 72.9%
3278372 101.1.9.16 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain › HTH_17 0.71 47.0 5.18e-01 97.6% 86.2%
3385701 101.1.9.95 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain › DUF3972 0.71 44.0 5.19e-01 84.1% 94.5%
5028046 101.1.9.0 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain 0.69 45.0 5.30e-01 84.1% 100.0%
3281256 101.1.9.16 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain › HTH_17 0.68 49.0 4.99e-01 86.6% 77.5%
3999520 108.1.1.0 ↗ alpha arrays › EF-hand › EF-hand-related › EF-hand 0.66 50.0 4.41e-01 87.8% 55.0%
3962562 101.1.9.0 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain 0.66 47.0 4.27e-01 73.2% 86.7%
3954117 101.1.9.16 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain › HTH_17 0.65 47.0 4.68e-01 85.4% 74.1%
3277144 108.1.1.0 ↗ alpha arrays › EF-hand › EF-hand-related › EF-hand 0.65 57.0 5.49e-01 100.0% 91.6%
3589130 101.1.9.16 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain › HTH_17 0.65 42.0 4.85e-01 84.1% 100.0%
3272220 108.1.1.0 ↗ alpha arrays › EF-hand › EF-hand-related › EF-hand 0.64 55.0 5.05e-01 93.9% 84.8%
3170713 108.1.1.0 ↗ alpha arrays › EF-hand › EF-hand-related › EF-hand 0.63 56.0 3.73e-01 98.8% 79.0%
3604634 101.1.9.0 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain 0.62 43.0 4.83e-01 84.1% 100.0%
5040722 101.1.9.0 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain 0.62 41.0 4.60e-01 85.4% 93.3%
5030468 101.1.9.0 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain 0.62 43.0 4.21e-01 73.2% 67.8%
3709334 108.1.1.0 ↗ alpha arrays › EF-hand › EF-hand-related › EF-hand 0.61 50.0 4.82e-01 95.1% 81.1%
1182022 101.1.2.122 ↗ alpha arrays › HTH › HTH › winged helix domain › CSN8_PSD8_EIF3K 0.60 35.0 3.92e-01 74.4% 76.7%
3607656 108.1.1.0 ↗ alpha arrays › EF-hand › EF-hand-related › EF-hand 0.60 50.0 4.79e-01 95.1% 81.1%
4951928 101.1.9.75 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain › DUF61 0.59 40.0 4.47e-01 85.4% 93.7%
5001454 101.1.9.0 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain 0.59 43.0 4.47e-01 79.3% 97.3%
3587304 101.1.9.0 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain 0.59 39.0 3.95e-01 76.8% 67.1%
159882 108.1.1.37 ↗ alpha arrays › EF-hand › EF-hand-related › EF-hand › AIF-1 0.58 51.0 4.21e-01 100.0% 54.0%
3924040 101.1.15.1 ↗ alpha arrays › HTH › HTH › HAT1, C-terminal domain › MOZ_SAS 0.58 42.0 4.39e-01 93.9% 84.0%
1291877 101.1.2.122 ↗ alpha arrays › HTH › HTH › winged helix domain › CSN8_PSD8_EIF3K 0.58 35.0 3.42e-01 75.6% 53.9%
142831 101.1.2.110 ↗ alpha arrays › HTH › HTH › winged helix domain › HTH_IclR 0.57 36.0 3.69e-01 79.3% 64.6%
3654295 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.57 42.0 4.16e-01 87.8% 72.7%
5044182 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.56 37.0 3.69e-01 79.3% 64.7%
5046808 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.55 33.0 2.64e-01 74.4% 28.5%
4948782 101.1.2.136 ↗ alpha arrays › HTH › HTH › winged helix domain › HTH_20 0.54 36.0 3.73e-01 95.1% 74.7%
5057371 3352.1.1.0 ↗ alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain 0.54 39.0 2.56e-01 79.3% 95.2%
3781952 101.1.2.45 ↗ alpha arrays › HTH › HTH › winged helix domain › SAC3_GANP 0.54 43.0 4.00e-01 87.8% 72.4%
5048731 101.1.2.927 ↗ alpha arrays › HTH › HTH › winged helix domain › DUF7347 0.54 36.0 3.49e-01 82.9% 60.0%
4354139 242.4.1.2 ↗ a+b two layers › Homing endonucleases-like › DNA polymerase II large subunit DP2 central a+b domain › DNA polymerase II large subunit DP2 central a+b domain › PolC_DP2_central 0.52 41.0 3.89e-01 89.0% 78.1%
4968640 242.4.1.0 ↗ a+b two layers › Homing endonucleases-like › DNA polymerase II large subunit DP2 central a+b domain › DNA polymerase II large subunit DP2 central a+b domain 0.52 40.0 3.69e-01 85.4% 71.8%
4666956 242.4.1.0 ↗ a+b two layers › Homing endonucleases-like › DNA polymerase II large subunit DP2 central a+b domain › DNA polymerase II large subunit DP2 central a+b domain 0.51 41.0 3.82e-01 89.0% 79.0%
5055051 242.4.1.2 ↗ a+b two layers › Homing endonucleases-like › DNA polymerase II large subunit DP2 central a+b domain › DNA polymerase II large subunit DP2 central a+b domain › PolC_DP2_central 0.51 40.0 3.81e-01 90.2% 76.2%
3485346 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.51 37.0 3.87e-01 86.6% 85.3%
5056548 242.4.1.2 ↗ a+b two layers › Homing endonucleases-like › DNA polymerase II large subunit DP2 central a+b domain › DNA polymerase II large subunit DP2 central a+b domain › PolC_DP2_central 0.51 40.0 3.71e-01 89.0% 77.3%
3600167 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.51 38.0 3.44e-01 81.7% 74.8%
3413924 101.1.2.45 ↗ alpha arrays › HTH › HTH › winged helix domain › SAC3_GANP 0.50 37.0 3.51e-01 89.0% 64.0%
D2 medium residues 90-188
PDB
Domain cluster: rep: uncharacterized_Bro-N_domain-containing_protein__YP_003986616__Acanthamoeba_polyphaga_mimivirus__212035__D63-140
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02498.23 best Bro-N 42.2 1.50e-10 79.8% 69.8%
CATH (7)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2h1eA02 2.40.50.40 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.64 31.0 3.91e-01 83.8% 80.0%
4hplA00 3.10.260.40 Alpha Beta › Roll › Mlu1-box Binding Protein; DNA-binding Domain › BCL-6 corepressor, PCGF1 binding domain 0.55 48.0 4.68e-01 100.0% 87.6%
1khcA01 2.30.30.140 Mainly Beta › Roll › SH3 type barrels. › 0.52 25.0 2.98e-01 77.8% 66.2%
1qe5A00 3.40.50.1580 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleoside phosphorylase domain 0.52 37.0 2.81e-01 73.7% 91.7%
5xd6B01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.51 36.0 3.67e-01 87.9% 76.6%
3g1pA00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.51 37.0 2.84e-01 76.8% 65.5%
1bnkA00 3.10.300.10 Alpha Beta › Roll › 3-methyladenine DNA Glycosylase; Chain A › Methylpurine-DNA glycosylase (MPG) 0.50 39.0 3.24e-01 87.9% 94.0%
ECOD (12)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4033119 101.1.9.63 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain › Bro-N 0.89 60.0 6.06e-01 85.9% 69.0%
3163642 101.1.9.63 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain › Bro-N 0.83 63.0 6.07e-01 92.9% 70.9%
3731164 101.1.9.37 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain › CRC_subunit 0.68 53.0 5.13e-01 100.0% 73.7%
3192917 101.1.9.37 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain › CRC_subunit 0.62 53.0 4.78e-01 99.0% 68.1%
3928322 214.1.1.1 ↗ a+b two layers › SH2 › SH2 › SH2 › SH2 0.57 41.0 4.07e-01 74.7% 89.5%
4929550 4.6.1.2 ↗ beta barrels › SH3 › PRC-barrel domain › PRC-barrel domain › PRC 0.55 29.0 3.28e-01 91.9% 65.7%
1002489 101.1.9.19 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain › PUFD 0.54 48.0 4.59e-01 100.0% 87.3%
3587866 247.1.1.1 ↗ a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.53 38.0 2.94e-01 77.8% 76.7%
3925755 211.1.1.0 ↗ a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 0.53 24.0 2.99e-01 89.9% 66.7%
3660002 247.1.1.0 ↗ a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase 0.52 36.0 3.14e-01 89.9% 44.2%
4144582 2002.1.1.102 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › PHP 0.51 37.0 2.76e-01 78.8% 82.1%
3730121 109.4.1.356 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.50 39.0 2.62e-01 87.9% 38.6%
D3 medium residues 189-246
PDB