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uncovered_polypeptide_truncated_polyprotein

Euk-Vir

Sindbis_virus

uncovered_polypeptide_truncated_polyprotein__YP_006491225_0-750__Sindbis_virus__11034

Identity

Accession:: YP_006491225_0-750 ↗
Protein ID:: uncovered_polypeptide_truncated_polyprotein
Kingdom:: euk

Quality

74.0 mean pLDDT

Taxonomy

Orthornavirae› Kitrinoviricota› Alsuviricetes› Martellivirales› Togaviridae› Alphavirus› Sindbis_virus

TaxID: 11034

Cluster

View cluster (12 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 273-330

PDB

Domain cluster: rep: polyprotein_cleavage_product_E3__YP_009509019__Everglades_virus__2083198__D6-52

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF01563.22 best	Alpha_E3_glycop	112.7	8.90e-33	96.5%	100.0%

D2 high residues 503-566

PDB

Domain cluster: rep: structural_protein__YP_010087635__Caaingua_virus__2499242__D507-563

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00943.26 best	Alpha_E2_glycop	89.1	3.70e-25	100.0%	15.4%

D3 medium residues 114-181

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00944.26 best	Peptidase_S3	127.1	8.00e-37	100.0%	42.8%

CATH (31)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1ep5A01	2.40.10.10	Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases	0.93	83.0	8.55e-01	95.6%	100.0%
2w5eA01	2.40.10.10	Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases	0.70	54.0	5.54e-01	83.8%	93.8%
1faxA02	2.40.10.10	Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases	0.68	58.0	4.99e-01	94.1%	86.9%
1zvpD00	3.30.2130.10	Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like	0.63	47.0	3.84e-01	80.9%	87.0%
1vq8E02	3.90.930.12	Alpha Beta › Alpha-Beta Complex › Outer Surface Protein A; domain 3 › Ribosomal protein L6	0.61	37.0	3.34e-01	86.8%	44.1%
7plsA02	2.60.40.1180	Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II	0.59	44.0	4.07e-01	83.8%	97.8%
4aw8A00	2.40.128.20	Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain	0.58	40.0	2.95e-01	72.1%	38.2%
1wczA01	2.40.10.10	Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases	0.57	46.0	3.92e-01	89.7%	68.7%
4lq0A01	3.10.28.10	Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases	0.56	48.0	3.81e-01	97.1%	90.3%
5n70A02	2.40.70.10	Mainly Beta › Beta Barrel › Cathepsin D, subunit A; domain 1 › Acid Proteases	0.55	45.0	3.65e-01	100.0%	88.8%
3w1zC00	2.60.40.790	Mainly Beta › Sandwich › Immunoglobulin-like ›	0.55	43.0	3.55e-01	86.8%	86.9%
1whrA00	3.30.1370.50	Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › R3H-like domain	0.54	39.0	3.31e-01	79.4%	61.3%
1kxqE00	2.60.40.10	Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins	0.54	38.0	3.25e-01	76.5%	95.8%
3bpsA02	2.60.120.690	Mainly Beta › Sandwich › Jelly Rolls › Proprotein convertase subtilisin/kexin type 9	0.53	38.0	3.12e-01	79.4%	42.7%
8begA02	2.60.40.740	Mainly Beta › Sandwich › Immunoglobulin-like ›	0.53	43.0	3.47e-01	97.1%	93.1%
4u7mA02	2.60.40.10	Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins	0.53	36.0	3.36e-01	73.5%	93.7%
4tshB01	2.60.40.740	Mainly Beta › Sandwich › Immunoglobulin-like ›	0.53	44.0	3.41e-01	98.5%	75.1%
1dpjA02	2.40.70.10	Mainly Beta › Beta Barrel › Cathepsin D, subunit A; domain 1 › Acid Proteases	0.53	42.0	3.48e-01	100.0%	81.8%
4d4iA01	3.40.50.12780	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain	0.52	42.0	2.66e-01	92.6%	62.8%
8begA03	2.60.40.740	Mainly Beta › Sandwich › Immunoglobulin-like ›	0.52	42.0	3.47e-01	98.5%	94.0%
2woyA02	2.60.40.740	Mainly Beta › Sandwich › Immunoglobulin-like ›	0.52	42.0	3.40e-01	98.5%	93.7%
5yxkA00	2.60.40.10	Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins	0.51	37.0	3.27e-01	79.4%	70.0%
2cpjA00	3.30.70.330	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain	0.51	35.0	3.17e-01	72.1%	77.8%
2nraC01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.51	43.0	3.45e-01	100.0%	88.7%
4g7wA00	2.40.30.280	Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Vibrio phage CTXphi pIII, N-terminal N1 domain	0.51	34.0	3.09e-01	70.6%	82.7%
4ofqA02	2.60.40.740	Mainly Beta › Sandwich › Immunoglobulin-like ›	0.51	41.0	3.36e-01	100.0%	93.5%
3l4gB03	3.30.56.10	Alpha Beta › 2-Layer Sandwich › Phenylalanyl-tRNA Synthetase; Chain B, domain 1 ›	0.51	34.0	3.38e-01	70.6%	77.0%
5e99H01	2.60.40.10	Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins	0.50	36.0	2.79e-01	77.9%	78.9%
2xzm901	6.20.50.180	Special › Other non-globular › N-terminal domain of TfIIb ›	0.50	37.0	3.66e-01	98.5%	75.0%
2b0lC00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.50	37.0	3.41e-01	82.4%	78.7%
7kbrC01	2.60.40.1180	Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II	0.50	38.0	3.15e-01	85.3%	74.6%

ECOD (23)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2429362	1.1.5.4 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Peptidase_S3	0.84	76.0	5.52e-01	100.0%	61.7%
3269940	1.1.17.0 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2	0.69	59.0	4.01e-01	100.0%	71.1%
3559927	1.1.17.1 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin	0.66	57.0	3.94e-01	100.0%	71.4%
4200480	318.1.1.1 ↗	a+b two layers › Ribosomal protein L6 › Ribosomal protein L6 › Ribosomal protein L6 › Ribosomal_L6	0.60	35.0	3.08e-01	89.7%	38.0%
3249347	11.1.1.0 ↗	beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like	0.58	45.0	4.33e-01	85.3%	100.0%
3705413	1.1.7.0 ↗	beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C	0.58	45.0	4.06e-01	85.3%	86.3%
5069267	318.1.1.1 ↗	a+b two layers › Ribosomal protein L6 › Ribosomal protein L6 › Ribosomal protein L6 › Ribosomal_L6	0.57	33.0	3.14e-01	89.7%	46.3%
3483327	11.1.1.0 ↗	beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like	0.57	43.0	3.55e-01	85.3%	90.0%
3185841	320.1.1.0 ↗	a+b two layers › R3H domain-like › R3H domain › R3H domain	0.55	39.0	3.90e-01	75.0%	100.0%
4462906	101.1.9.5 ↗	alpha arrays › HTH › HTH › Putative DNA-binding domain › B5	0.55	38.0	3.43e-01	70.6%	69.5%
3699601	319.1.1.0 ↗	beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones	0.53	39.0	3.80e-01	79.4%	100.0%
3590065	11.1.5.50 ↗	beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f › AgI_II_C2	0.53	44.0	3.58e-01	100.0%	90.7%
4075706	11.2.1.8 ↗	beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › PTEN_C2	0.53	36.0	3.19e-01	73.5%	81.7%
3587183	11.1.5.50 ↗	beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f › AgI_II_C2	0.53	43.0	3.46e-01	100.0%	89.1%
3508541	101.1.2.16 ↗	alpha arrays › HTH › HTH › winged helix domain › Rep3_N	0.53	44.0	3.68e-01	98.5%	96.2%
3499010	11.1.1.0 ↗	beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like	0.52	38.0	3.26e-01	80.9%	93.5%
3885649	11.1.1.99 ↗	beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › V-set	0.52	37.0	2.97e-01	79.4%	67.7%
5011372	306.6.1.0 ↗	a+b two layers › Glucose permease domain IIB-like › PH0987 N-terminal domain-like › PH0987 N-terminal domain-like	0.52	41.0	3.74e-01	89.7%	81.1%
3366240	12.1.1.63 ↗	beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain › Raffinose_syn	0.51	41.0	3.70e-01	94.1%	61.8%
4937614	242.1.1.0 ↗	a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases	0.51	42.0	3.36e-01	92.6%	43.4%
3669480	12.1.1.63 ↗	beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain › Raffinose_syn	0.51	41.0	3.70e-01	94.1%	71.8%
3986771	101.1.2.16 ↗	alpha arrays › HTH › HTH › winged helix domain › Rep3_N	0.51	43.0	3.58e-01	100.0%	94.6%
4612833	323.1.1.3 ↗	a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding	0.50	40.0	2.80e-01	92.6%	96.9%

D4 medium residues 182-268

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00944.26 best	Peptidase_S3	182.5	7.20e-54	96.5%	52.8%

CATH (18)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1ep5A02	2.40.10.10	Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases	0.98	91.0	9.22e-01	95.4%	96.5%
1agjA01	2.40.10.10	Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases	0.78	57.0	4.88e-01	75.9%	61.2%
1arbA01	2.40.10.10	Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases	0.78	57.0	5.08e-01	77.0%	77.9%
1wczA01	2.40.10.10	Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases	0.75	59.0	5.34e-01	82.8%	74.8%
3k6yA02	2.40.10.10	Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases	0.75	60.0	5.55e-01	83.9%	88.8%
4b6eB01	2.40.10.120	Mainly Beta › Beta Barrel › Thrombin, subunit H ›	0.74	65.0	4.90e-01	95.4%	46.5%
1a1rA02	2.40.10.10	Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases	0.73	57.0	5.83e-01	82.8%	96.5%
3l6pA02	2.40.10.10	Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases	0.72	55.0	5.18e-01	80.5%	73.3%
5hmaA02	2.40.10.10	Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases	0.70	54.0	5.14e-01	82.8%	90.4%
2ey4D00	2.40.10.230	Mainly Beta › Beta Barrel › Thrombin, subunit H › Probable tRNA pseudouridine synthase domain	0.69	48.0	5.11e-01	71.3%	82.7%
2w5eA02	2.40.10.10	Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases	0.67	49.0	5.30e-01	78.2%	97.3%
3u28C00	2.40.10.230	Mainly Beta › Beta Barrel › Thrombin, subunit H › Probable tRNA pseudouridine synthase domain	0.67	47.0	4.65e-01	74.7%	69.6%
2dpyA00	3.40.50.12240	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.60	45.0	2.92e-01	80.5%	60.2%
2gfaB01	2.30.30.140	Mainly Beta › Roll › SH3 type barrels. ›	0.57	33.0	3.78e-01	78.2%	79.0%
3v8uA03	2.40.128.240	Mainly Beta › Beta Barrel › Lipocalin ›	0.56	35.0	3.53e-01	88.5%	60.0%
3k5iA03	3.30.470.20	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain	0.51	41.0	3.20e-01	88.5%	89.9%
1xn5A00	3.30.530.20	Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain	0.50	33.0	2.91e-01	79.3%	42.8%
2dt4A00	3.30.1330.80	Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › Hypothetical protein, similar to alpha- acetolactate decarboxylase; domain 2	0.50	39.0	3.44e-01	88.5%	93.0%

ECOD (19)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4881628	1.1.5.4 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Peptidase_S3	0.95	86.0	8.90e-01	94.3%	100.0%
2429362	1.1.5.4 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Peptidase_S3	0.92	84.0	6.37e-01	96.6%	46.1%
4620869	1.1.5.57 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Mycop_pep_DUF31	0.79	62.0	4.06e-01	83.9%	38.4%
4059005	1.1.17.23 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Peptidase_S7	0.76	60.0	4.24e-01	83.9%	52.7%
3674829	1.1.13.61 ↗	beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins › Gar1	0.74	52.0	5.72e-01	72.4%	100.0%
3654499	1.1.5.33 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2	0.73	57.0	5.03e-01	82.8%	76.0%
2716345	1.4.1.1 ↗	beta barrels › cradle loop barrel › N-terminal domain of poxin › N-terminal domain of poxin › Baculo_p26	0.72	56.0	4.57e-01	83.9%	59.7%
3248403	1.1.5.0 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel	0.70	54.0	4.68e-01	82.8%	57.8%
4499041	1.1.5.57 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Mycop_pep_DUF31	0.69	54.0	4.10e-01	83.9%	52.7%
4881914	1.1.5.33 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2	0.69	54.0	4.10e-01	83.9%	41.8%
5077063	1.1.7.20 ↗	beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › Gar1	0.68	46.0	4.95e-01	70.1%	81.3%
4259810	1.1.7.20 ↗	beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › Gar1	0.68	47.0	4.93e-01	73.6%	78.8%
4964309	1.1.7.20 ↗	beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › Gar1	0.68	47.0	5.05e-01	72.4%	86.5%
4525111	1.1.7.126 ↗	beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › Peptidase_S7	0.65	46.0	4.76e-01	72.4%	100.0%
5041607	1.1.7.0 ↗	beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C	0.65	45.0	4.86e-01	74.7%	85.1%
5051893	1.1.7.20 ↗	beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › Gar1	0.65	45.0	4.70e-01	72.4%	86.3%
4263415	1.1.7.20 ↗	beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › Gar1	0.58	46.0	4.63e-01	86.2%	87.8%
2869319	1.1.7.20 ↗	beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › Gar1	0.57	46.0	4.48e-01	86.2%	84.7%
3387360	1.1.7.0 ↗	beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C	0.55	42.0	4.31e-01	86.2%	85.9%

D5 medium residues 331-462

PDB

Domain cluster: rep: E2_protein__NP_819006__Semliki_Forest_virus__11033__D2-168

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00943.26 best	Alpha_E2_glycop	203.7	6.00e-60	93.9%	30.3%

D6 medium residues 463-502_572-599

PDB

Domain cluster: rep: uncovered_polypeptide_truncated_polyprotein__YP_006491227_0-741__Western_equine_encephalitis_virus__11039__D454-491_575-588

Pfam (2)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00943.26 best	Alpha_E2_glycop	61.0	1.20e-16	60.3%	9.9%
PF00943.26	Alpha_E2_glycop	37.9	1.30e-09	42.6%	7.0%

D7 medium residues 600-671

PDB

Domain cluster: rep: E2_protein__NP_740659__Sleeping_disease_virus__78540__D289-352

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00943.26 best	Alpha_E2_glycop	121.3	6.40e-35	100.0%	17.9%