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uracil-DNA_glycosylase

Euk-Vir

Human_alphaherpesvirus_3

uracil-DNA_glycosylase__NP_040181__Human_alphaherpesvirus_3__10335

Identity

Accession:
NP_040181 ↗
Protein ID:
uracil-DNA_glycosylase
Kingdom:
euk

Quality

81.7 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 135-295
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03167.26 best UDG 67.8 1.50e-18 98.8% 97.1%
D2 medium residues 79-134
PDB
Domain cluster: representative
CATH (6)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2c53A00 3.40.470.10 Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain 0.96 89.0 5.63e-01 100.0% 24.1%
4r24B00 1.10.1660.10 Mainly Alpha › Orthogonal Bundle › Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 › 0.58 45.0 3.96e-01 83.9% 71.8%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.58 46.0 3.84e-01 92.9% 89.1%
4fvmA04 6.10.10.100 Special › Helix non-globular › Helicase, Ruva Protein; domain 3 › 0.55 34.0 3.68e-01 87.5% 73.9%
2yf4F00 1.10.3420.10 Mainly Alpha › Orthogonal Bundle › putative ntp pyrophosphohydrolase like fold › putative ntp pyrophosphohydrolase like domain 0.53 41.0 3.12e-01 85.7% 62.2%
5ayvA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.52 42.0 3.44e-01 100.0% 53.6%
ECOD (3)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3171107 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.88 82.0 5.08e-01 100.0% 23.8%
3343787 109.4.1.1374 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, TPR_24 0.64 44.0 3.11e-01 71.4% 60.6%
3261307 109.4.1.2 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Arm 0.60 44.0 2.55e-01 78.6% 9.0%