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uracil-DNA_glycosylase

Euk-Vir

Anguillid_herpesvirus_1

uracil-DNA_glycosylase__YP_003358168__Anguillid_herpesvirus_1__150286

Identity

Accession:
YP_003358168 ↗
Protein ID:
uracil-DNA_glycosylase
Kingdom:
euk

Quality

75.5 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 134-303
PDB
CATH (46)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2booA00 3.40.470.10 Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain 0.86 82.0 7.26e-01 100.0% 73.0%
2c53A00 3.40.470.10 Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain 0.86 81.0 7.20e-01 100.0% 73.2%
6lydA01 3.40.470.10 Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain 0.84 81.0 6.94e-01 100.0% 76.9%
3nt7A00 3.40.470.10 Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain 0.81 71.0 6.43e-01 100.0% 71.0%
3iprA00 3.40.50.510 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphotransferase system, mannose-type IIA component 0.66 44.0 4.88e-01 93.5% 83.2%
2qu7A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.60 42.0 4.64e-01 86.5% 87.7%
3gv0A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.60 40.0 4.45e-01 84.7% 85.7%
4rhiA00 3.40.800.10 Alpha Beta › 3-Layer(aba) Sandwich › Arginase; Chain A › Ureohydrolase domain 0.59 54.0 4.39e-01 100.0% 95.3%
4ru1A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.59 39.0 4.15e-01 85.3% 75.7%
7w6bA01 3.40.50.410 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain 0.58 49.0 4.19e-01 89.4% 99.3%
6feaB01 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.58 42.0 4.50e-01 90.0% 86.3%
4wutA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.58 39.0 4.13e-01 85.3% 76.3%
3hcwA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.58 41.0 4.42e-01 91.2% 86.0%
3egcD02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.57 37.0 4.23e-01 86.5% 86.0%
3pdiA01 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.57 41.0 4.35e-01 91.2% 81.8%
4dz4A00 3.40.800.10 Alpha Beta › 3-Layer(aba) Sandwich › Arginase; Chain A › Ureohydrolase domain 0.57 51.0 4.19e-01 97.6% 88.8%
3nyiB01 3.40.50.10170 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.56 46.0 4.78e-01 93.5% 92.4%
7esrA01 3.40.800.10 Alpha Beta › 3-Layer(aba) Sandwich › Arginase; Chain A › Ureohydrolase domain 0.56 51.0 4.01e-01 98.2% 82.8%
2a0mA00 3.40.800.10 Alpha Beta › 3-Layer(aba) Sandwich › Arginase; Chain A › Ureohydrolase domain 0.56 50.0 4.16e-01 96.5% 96.0%
2jgdA04 3.40.50.11610 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain 0.56 42.0 4.34e-01 98.8% 83.0%
3lhlA00 3.40.800.10 Alpha Beta › 3-Layer(aba) Sandwich › Arginase; Chain A › Ureohydrolase domain 0.56 50.0 4.24e-01 96.5% 100.0%
1gq6B00 3.40.800.10 Alpha Beta › 3-Layer(aba) Sandwich › Arginase; Chain A › Ureohydrolase domain 0.56 50.0 4.14e-01 97.6% 95.3%
1wohA00 3.40.800.10 Alpha Beta › 3-Layer(aba) Sandwich › Arginase; Chain A › Ureohydrolase domain 0.55 49.0 4.07e-01 97.6% 94.1%
3l49A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.54 39.0 4.15e-01 85.3% 84.4%
3t5tB01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.54 47.0 3.92e-01 93.5% 98.3%
5hj9A00 3.40.800.10 Alpha Beta › 3-Layer(aba) Sandwich › Arginase; Chain A › Ureohydrolase domain 0.54 46.0 3.81e-01 92.9% 99.7%
4rpcA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.53 49.0 4.30e-01 99.4% 100.0%
3fniA00 3.40.50.360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain 0.53 43.0 4.56e-01 95.9% 96.8%
4f1jA00 3.40.50.410 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain 0.53 45.0 4.32e-01 92.9% 97.5%
4dcuA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.53 41.0 4.44e-01 93.5% 98.6%
3vbcA00 3.40.50.11530 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.53 39.0 4.32e-01 95.3% 97.8%
4dqlA03 3.40.50.80 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module 0.53 42.0 4.31e-01 83.5% 95.7%
1r1dA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.52 48.0 4.27e-01 100.0% 98.8%
3czpB01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 45.0 4.20e-01 93.5% 81.2%
3t8iA00 3.90.245.10 Alpha Beta › Alpha-Beta Complex › Inosine-uridine Nucleoside N-ribohydrolase; Chain A › Ribonucleoside hydrolase-like 0.52 45.0 3.63e-01 91.2% 81.0%
6h0cA02 3.40.50.360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain 0.51 42.0 4.45e-01 92.4% 99.3%
1fmcA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.51 43.0 3.81e-01 91.2% 88.6%
2bpoA04 3.40.50.80 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module 0.51 41.0 4.20e-01 83.5% 95.7%
1zbqA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.51 43.0 3.89e-01 92.9% 91.0%
4d02A02 3.40.50.360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain 0.51 41.0 4.36e-01 89.4% 100.0%
2qtlA03 3.40.50.80 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module 0.51 40.0 4.22e-01 83.5% 100.0%
3qyfA01 3.40.50.10770 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Hypothetical protein VC1899 like domain (Restriction endonuclease-like) 0.51 42.0 4.30e-01 89.4% 96.4%
2fzvA00 3.40.50.360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain 0.51 46.0 4.15e-01 100.0% 89.8%
1nni100 3.40.50.360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain 0.50 44.0 4.43e-01 93.5% 98.2%
1tt5C01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.50 43.0 3.55e-01 93.5% 85.3%
4trrG00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.50 43.0 3.96e-01 93.5% 90.7%
ECOD (56)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3171107 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.86 83.0 6.89e-01 100.0% 67.8%
3837322 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.86 82.0 6.88e-01 100.0% 64.6%
3592251 7569.1.1.0 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like 0.85 81.0 7.14e-01 100.0% 72.8%
4168074 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.84 81.0 7.08e-01 100.0% 70.8%
5066830 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.69 63.0 6.09e-01 98.8% 87.9%
3587669 2010.1.1.3 a/b three-layered sandwiches › EDD domain › EDD domain › EDD domain › EIIA-man 0.67 45.0 4.90e-01 93.5% 81.4%
2070922 7569.1.1.0 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like 0.65 61.0 5.15e-01 100.0% 62.5%
5026550 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.60 40.0 4.77e-01 90.0% 100.0%
5017064 2007.1.8.1 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Uroporphyrinogen III synthase (U3S, HemD) › HEM4 0.60 44.0 4.96e-01 88.8% 100.0%
1653219 2007.1.2.10 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_3 0.60 39.0 4.44e-01 85.9% 86.9%
1252849 2007.1.2.10 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_3 0.59 41.0 4.50e-01 85.9% 86.0%
4991816 2007.1.11.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › L-fucose isomerase, N-terminal and second domains 0.59 43.0 4.80e-01 92.9% 97.7%
4438178 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.59 48.0 3.57e-01 87.1% 75.2%
5072638 7569.1.1.2 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › DUF5591 0.59 51.0 5.27e-01 97.1% 100.0%
4990562 7522.1.1.1 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › Transketolase_C 0.59 46.0 4.98e-01 100.0% 98.6%
3498878 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.58 47.0 3.64e-01 87.1% 84.1%
3355925 7579.1.1.0 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases 0.58 49.0 4.00e-01 91.8% 87.3%
3427403 2008.1.1.151 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PF28664 0.57 45.0 4.59e-01 82.9% 90.3%
5001177 2007.1.11.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › L-fucose isomerase, N-terminal and second domains 0.57 42.0 4.70e-01 93.5% 96.3%
3698631 2006.1.5.1 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Arginase/deacetylase › Arginase 0.56 50.0 4.15e-01 96.5% 95.3%
None 0.56 51.0 3.68e-01 99.4% 68.2%
3885165 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.56 51.0 3.66e-01 100.0% 72.2%
4027831 7579.1.1.0 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases 0.56 44.0 3.95e-01 82.4% 94.4%
3720072 7512.1.1.54 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Alg14 0.56 47.0 4.13e-01 90.0% 82.4%
5001011 2006.1.5.1 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Arginase/deacetylase › Arginase 0.55 49.0 4.08e-01 97.1% 94.8%
None 0.55 48.0 3.54e-01 95.9% 69.3%
5024065 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.55 38.0 4.12e-01 93.5% 86.7%
9949 2006.1.5.1 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Arginase/deacetylase › Arginase 0.55 49.0 4.07e-01 97.6% 94.1%
5075835 2484.1.1.38 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › eRF1_2 0.55 40.0 4.51e-01 94.1% 100.0%
5008810 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.55 40.0 4.42e-01 88.8% 94.8%
4996929 2002.1.1.152 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Amidohydro_3 0.54 45.0 3.31e-01 88.2% 75.3%
4418276 2006.1.5.1 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Arginase/deacetylase › Arginase 0.54 49.0 4.12e-01 99.4% 97.9%
3232001 2007.1.2.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I 0.54 46.0 3.37e-01 92.9% 78.8%
5067622 2006.1.5.1 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Arginase/deacetylase › Arginase 0.54 49.0 4.17e-01 99.4% 99.6%
5048331 2007.6.1.5 a/b three-layered sandwiches › Flavodoxin-like › Ribosomal protein S2/SIS domain › Ribosomal protein S2/SIS domain › bact-PGI_C 0.54 37.0 3.68e-01 92.9% 65.0%
4009532 2004.1.1.73 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 0.54 47.0 4.00e-01 93.5% 66.2%
5011229 2006.1.5.1 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Arginase/deacetylase › Arginase 0.54 49.0 4.13e-01 100.0% 99.0%
3281683 2002.1.1.274 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Amidohydro_1, Amidohydro_3 0.53 44.0 3.19e-01 88.8% 72.1%
3933502 7512.1.1.54 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Alg14 0.53 43.0 4.07e-01 85.3% 86.0%
4967499 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.53 46.0 4.30e-01 93.5% 100.0%
3731744 7514.1.1.1 a/b three-layered sandwiches › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › NAD_binding_1 0.53 42.0 4.21e-01 82.4% 91.2%
4976814 2003.1.9.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Activating enzymes of the ubiquitin-like proteins 0.53 45.0 4.01e-01 93.5% 84.4%
3315815 7512.1.1.54 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Alg14 0.53 42.0 3.80e-01 85.3% 75.2%
4938284 2006.1.5.1 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Arginase/deacetylase › Arginase 0.52 46.0 4.07e-01 95.3% 100.0%
5061381 7563.1.1.2 a/b three-layered sandwiches › MCP/YpsA-related › MCP/YpsA-related › MCP/YpsA-related › Lysine_decarbox 0.52 45.0 4.29e-01 95.3% 93.7%
3584678 2003.1.5.97 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_32 0.51 39.0 3.72e-01 79.4% 98.5%
4957252 2004.1.1.14 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › GTP_EFTU 0.51 44.0 4.52e-01 92.4% 98.8%
5074332 2004.1.1.206 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_31 0.51 42.0 3.72e-01 89.4% 98.1%
4646068 2006.1.3.5 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › DUF2100 0.51 35.0 3.85e-01 91.2% 89.2%
5061175 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.51 41.0 4.09e-01 84.7% 96.6%
3279729 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.51 43.0 3.82e-01 92.4% 95.2%
4221949 2007.2.1.2 a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Flavoproteins › Flavodoxin_2 0.50 44.0 4.07e-01 93.5% 98.6%
4959777 7512.1.1.0 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase 0.50 41.0 4.06e-01 85.3% 98.3%
3627662 2007.15.1.9 a/b three-layered sandwiches › Flavodoxin-like › N-deoxyribosyltransferase › N-deoxyribosyltransferase › MAP3K_TRAF_bd, DRHyd-ASK 0.50 43.0 4.26e-01 92.4% 99.4%
4962016 7512.1.1.31 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_trans_4_4 0.50 42.0 4.42e-01 90.0% 100.0%
4131081 2007.2.1.1 a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Flavoproteins › Flavodoxin_1 0.50 41.0 4.19e-01 93.5% 91.3%
D2 medium residues 74-133
PDB
Domain cluster: representative