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uracil-DNA_glycosylase_repair_protein
Euk-VirPithovirus_sibericum
uracil-DNA_glycosylase_repair_protein__YP_009001318__Pithovirus_sibericum__1450746
Identity
- Accession:
- YP_009001318 ↗
- Protein ID:
- uracil-DNA_glycosylase_repair_protein
- Kingdom:
- euk
Quality
96.2
mean pLDDT
Cluster
View cluster (62 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 64-227
Domain cluster:
rep: MK016493.1__AYQ99350.1__PBI_CANTARE_130__00130__D75-228
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03167.26 best | UDG | 51.3 | 1.90e-13 | 98.8% | 95.7% |
CATH (40)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6lydA01 | 3.40.470.10 | Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain | 0.93 | 90.0 | 7.64e-01 | 100.0% | 74.5% |
| 2booA00 | 3.40.470.10 | Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain | 0.91 | 87.0 | 7.58e-01 | 100.0% | 70.4% |
| 2c53A00 | 3.40.470.10 | Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain | 0.89 | 84.0 | 7.38e-01 | 100.0% | 70.6% |
| 3nt7A00 | 3.40.470.10 | Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain | 0.86 | 75.0 | 6.68e-01 | 100.0% | 68.2% |
| 2c2pA01 | 3.40.470.10 | Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain | 0.70 | 66.0 | 6.52e-01 | 100.0% | 98.2% |
| 1pq4A02 | 3.40.50.1980 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain | 0.66 | 41.0 | 4.95e-01 | 96.3% | 97.1% |
| 2prsA02 | 3.40.50.1980 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain | 0.63 | 42.0 | 4.94e-01 | 97.6% | 97.4% |
| 5exeA02 | 3.40.50.920 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.63 | 46.0 | 4.95e-01 | 100.0% | 86.8% |
| 3gdwB00 | 3.40.50.510 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphotransferase system, mannose-type IIA component | 0.61 | 41.0 | 4.42e-01 | 97.6% | 81.2% |
| 5cmlA00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.58 | 47.0 | 4.11e-01 | 85.4% | 94.2% |
| 3kcnB00 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.57 | 41.0 | 4.44e-01 | 96.3% | 89.1% |
| 3wj2B00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.56 | 46.0 | 3.85e-01 | 89.0% | 93.7% |
| 5d6oA00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.56 | 47.0 | 3.71e-01 | 90.2% | 98.6% |
| 4x90A01 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.56 | 50.0 | 4.63e-01 | 97.6% | 100.0% |
| 8ckpA01 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.55 | 45.0 | 3.83e-01 | 88.4% | 90.1% |
| 3nwoA00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.55 | 48.0 | 3.98e-01 | 95.7% | 90.3% |
| 1mtzA00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.55 | 47.0 | 3.94e-01 | 94.5% | 90.7% |
| 3u7qB01 | 3.40.50.1980 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain | 0.54 | 40.0 | 4.20e-01 | 94.5% | 85.6% |
| 2o2gA00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.54 | 49.0 | 4.50e-01 | 100.0% | 97.7% |
| 5egnA00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.53 | 43.0 | 3.76e-01 | 87.2% | 98.8% |
| 1r3dA00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.53 | 46.0 | 4.00e-01 | 94.5% | 92.6% |
| 2w9xA02 | 3.40.50.1110 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase | 0.52 | 47.0 | 4.29e-01 | 99.4% | 99.6% |
| 2jfkA02 | 3.40.366.10 | Alpha Beta › 3-Layer(aba) Sandwich › Malonyl-Coenzyme A Acyl Carrier Protein; domain 2 › Malonyl-Coenzyme A Acyl Carrier Protein, domain 2 | 0.52 | 46.0 | 4.02e-01 | 95.7% | 100.0% |
| 6kd0A01 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.52 | 47.0 | 3.81e-01 | 99.4% | 79.6% |
| 1iukA00 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.52 | 37.0 | 4.00e-01 | 88.4% | 87.5% |
| 4fi3F02 | 3.40.50.1980 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain | 0.52 | 35.0 | 3.94e-01 | 95.1% | 89.7% |
| 7otsB01 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.52 | 48.0 | 3.97e-01 | 100.0% | 92.2% |
| 2wueA00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.51 | 47.0 | 3.90e-01 | 99.4% | 91.9% |
| 1wmdA01 | 3.40.50.200 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Peptidase S8/S53 domain | 0.51 | 45.0 | 3.68e-01 | 97.0% | 79.2% |
| 2xmzA00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.51 | 45.0 | 3.88e-01 | 96.3% | 94.7% |
| 5cygB00 | 3.40.50.1580 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleoside phosphorylase domain | 0.51 | 46.0 | 3.89e-01 | 98.8% | 91.8% |
| 1uqtA01 | 3.40.50.2000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; | 0.51 | 44.0 | 3.91e-01 | 94.5% | 98.4% |
| 4py5A02 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.51 | 41.0 | 3.94e-01 | 93.3% | 72.3% |
| 4rncA00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.51 | 46.0 | 3.90e-01 | 100.0% | 91.8% |
| 3czpB01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.51 | 46.0 | 4.21e-01 | 98.2% | 82.2% |
| 1imjA00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.51 | 44.0 | 4.07e-01 | 93.3% | 84.1% |
| 7jt8I01 | 3.40.1190.10 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Mur-like, catalytic domain | 0.51 | 45.0 | 4.04e-01 | 97.6% | 94.4% |
| 4do7A00 | 3.20.20.140 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases | 0.51 | 44.0 | 3.68e-01 | 94.5% | 97.9% |
| 2y6uA01 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.50 | 46.0 | 3.61e-01 | 100.0% | 87.8% |
| 5frdA00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.50 | 46.0 | 3.97e-01 | 100.0% | 91.4% |
ECOD (44)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2100092 | 7569.1.1.1 ↗ | a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG | 0.94 | 91.0 | 7.36e-01 | 100.0% | 66.7% |
| 3837322 | 7569.1.1.1 ↗ | a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG | 0.92 | 88.0 | 7.31e-01 | 100.0% | 62.3% |
| 4621405 | 7569.1.1.1 ↗ | a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG | 0.91 | 88.0 | 7.50e-01 | 100.0% | 76.6% |
| 3592251 | 7569.1.1.0 ↗ | a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like | 0.89 | 87.0 | 7.46e-01 | 100.0% | 70.2% |
| 4168074 | 7569.1.1.1 ↗ | a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG | 0.89 | 87.0 | 7.40e-01 | 100.0% | 68.3% |
| 4149039 | 7569.1.1.1 ↗ | a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG | 0.87 | 84.0 | 7.34e-01 | 100.0% | 73.0% |
| 985197 | 7569.1.1.1 ↗ | a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG | 0.86 | 74.0 | 6.73e-01 | 100.0% | 70.4% |
| 324235 | 7569.1.1.0 ↗ | a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like | 0.86 | 75.0 | 6.63e-01 | 100.0% | 66.5% |
| 4499054 | 7569.1.1.1 ↗ | a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG | 0.85 | 82.0 | 7.14e-01 | 100.0% | 73.0% |
| 5066830 | 7569.1.1.1 ↗ | a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG | 0.72 | 65.0 | 6.21e-01 | 98.8% | 83.7% |
| 4153941 | 7570.1.1.1 ↗ | a/b three-layered sandwiches › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › Mur_ligase_C | 0.68 | 37.0 | 4.04e-01 | 99.4% | 62.7% |
| 4649312 | 2007.1.14.4 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like › ZnuA | 0.62 | 38.0 | 4.39e-01 | 94.5% | 85.2% |
| 3970210 | 2007.1.14.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like | 0.60 | 40.0 | 4.56e-01 | 96.3% | 90.8% |
| 5063197 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.59 | 39.0 | 4.64e-01 | 97.6% | 100.0% |
| 4991799 | 2007.1.5.2 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › ATC-like › CCG | 0.58 | 37.0 | 4.36e-01 | 89.0% | 94.5% |
| 3733361 | 2007.1.3.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like | 0.58 | 39.0 | 4.35e-01 | 95.7% | 86.9% |
| 3286072 | 7579.1.1.95 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_1, Hydrolase_4 | 0.58 | 49.0 | 4.28e-01 | 92.1% | 97.6% |
| 4990589 | 2007.1.14.5 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like › Peripla_BP_2 | 0.57 | 36.0 | 4.24e-01 | 92.7% | 90.4% |
| 377439 | 2007.1.3.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg | 0.57 | 41.0 | 4.45e-01 | 96.3% | 89.7% |
| None | — | 0.56 | 48.0 | 3.84e-01 | 91.5% | 92.8% | |
| 4404187 | 2003.1.14.2 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Aspartate/ornithine carbamoyltransferase › OTCace_N | 0.56 | 35.0 | 3.66e-01 | 92.1% | 65.8% |
| 4014119 | 2006.1.1.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like | 0.55 | 45.0 | 3.85e-01 | 86.6% | 80.4% |
| None | — | 0.55 | 48.0 | 3.97e-01 | 94.5% | 90.7% | |
| 4968031 | 2007.1.3.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like | 0.55 | 42.0 | 4.51e-01 | 96.3% | 95.0% |
| 3667397 | 7512.1.1.0 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase | 0.54 | 45.0 | 3.88e-01 | 88.4% | 96.4% |
| 4395641 | 7570.1.1.1 ↗ | a/b three-layered sandwiches › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › Mur_ligase_C | 0.54 | 36.0 | 3.86e-01 | 81.7% | 78.6% |
| 4008873 | 4303.1.1.1 ↗ | alpha arrays › lvD/EDD N-terminal domain-like › lvD/EDD N-terminal domain-like › lvD/EDD N-terminal domain-like › ILVD_EDD | 0.53 | 48.0 | 3.58e-01 | 99.4% | 55.6% |
| 5007752 | 7512.1.1.30 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 | 0.53 | 48.0 | 4.51e-01 | 95.7% | 100.0% |
| 4978841 | 7513.1.1.1 ↗ | a/b three-layered sandwiches › CofD-like › CofD-like › CofD-like › CofD | 0.53 | 47.0 | 3.88e-01 | 98.8% | 97.1% |
| None | — | 0.53 | 46.0 | 4.00e-01 | 94.5% | 92.6% | |
| 5010709 | 7512.1.1.0 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase | 0.53 | 43.0 | 3.94e-01 | 87.2% | 90.9% |
| 3667008 | 7512.1.1.1 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDPGT | 0.52 | 44.0 | 3.64e-01 | 90.9% | 98.7% |
| 3425820 | 7579.1.1.44 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_6 | 0.52 | 45.0 | 3.59e-01 | 93.3% | 80.0% |
| 4348794 | 7570.1.1.1 ↗ | a/b three-layered sandwiches › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › Mur_ligase_C | 0.52 | 35.0 | 3.72e-01 | 83.5% | 76.6% |
| 4226665 | 7579.1.1.6 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_1 | 0.52 | 46.0 | 3.95e-01 | 95.7% | 93.0% |
| 4104733 | 7570.1.1.1 ↗ | a/b three-layered sandwiches › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › Mur_ligase_C | 0.52 | 34.0 | 3.64e-01 | 84.1% | 75.0% |
| None | — | 0.52 | 45.0 | 3.67e-01 | 94.5% | 82.6% | |
| 5035028 | 7512.1.1.62 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_trans_1_3 | 0.51 | 43.0 | 4.03e-01 | 90.2% | 97.1% |
| 3587040 | 7579.1.1.42 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Hydrolase_4 | 0.51 | 46.0 | 3.86e-01 | 100.0% | 77.6% |
| 4973354 | 7513.1.1.1 ↗ | a/b three-layered sandwiches › CofD-like › CofD-like › CofD-like › CofD | 0.51 | 45.0 | 3.69e-01 | 98.2% | 97.5% |
| 3673165 | 7579.1.1.6 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_1 | 0.51 | 47.0 | 3.66e-01 | 100.0% | 74.3% |
| 4046481 | 2007.1.3.28 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Glyco_transf_61 | 0.51 | 45.0 | 3.84e-01 | 98.8% | 59.5% |
| 3814009 | 7579.1.1.92 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_1, Abhydrolase_6 | 0.50 | 45.0 | 3.71e-01 | 99.4% | 87.2% |
| 4974804 | 7512.1.1.139 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › DUF1972 | 0.50 | 42.0 | 4.14e-01 | 89.6% | 97.7% |
D2
medium
residues 14-63
Domain cluster:
representative
ECOD (2)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3220759 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.56 | 46.0 | 3.65e-01 | 100.0% | 68.3% |
| 4990364 | 615.1.1.1 ↗ | alpha arrays › T4 endonuclease V › T4 endonuclease V › T4 endonuclease V › Pyr_excise | 0.53 | 44.0 | 3.29e-01 | 98.0% | 97.2% |