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vIRF-1

Euk-Vir

Human_gammaherpesvirus_8

vIRF-1__YP_001129411__Human_gammaherpesvirus_8__37296

Identity

Accession:
YP_001129411 ↗
Protein ID:
vIRF-1
Kingdom:
euk

Quality

67.6 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Rhadinovirus› Human_gammaherpesvirus_8

TaxID: 37296

Cluster

View cluster (18 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 252-448
PDB
Domain cluster: rep: JM98__YP_238401__Macaca_fuscata_rhadinovirus__272551__D238-410
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF10401.15 best IRF-3 53.8 2.90e-14 78.2% 71.1%
CATH (20)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5bviA00 2.60.200.10 Mainly Beta › Sandwich › Tumour Suppressor Smad4 › 0.85 71.0 7.46e-01 100.0% 94.0%
3dshA01 2.60.200.10 Mainly Beta › Sandwich › Tumour Suppressor Smad4 › 0.79 73.0 7.22e-01 100.0% 92.6%
5e50A01 2.60.200.20 Mainly Beta › Sandwich › Tumour Suppressor Smad4 › 0.79 42.0 5.74e-01 94.4% 100.0%
7cd1D01 2.60.200.10 Mainly Beta › Sandwich › Tumour Suppressor Smad4 › 0.79 65.0 6.91e-01 96.4% 95.4%
1zoqA00 2.60.200.10 Mainly Beta › Sandwich › Tumour Suppressor Smad4 › 0.78 69.0 7.04e-01 100.0% 94.2%
2jpeA00 2.60.200.20 Mainly Beta › Sandwich › Tumour Suppressor Smad4 › 0.77 44.0 5.31e-01 99.5% 84.1%
4h87A00 2.60.200.20 Mainly Beta › Sandwich › Tumour Suppressor Smad4 › 0.75 42.0 5.23e-01 98.0% 87.1%
1dd1A00 2.60.200.10 Mainly Beta › Sandwich › Tumour Suppressor Smad4 › 0.75 71.0 6.77e-01 100.0% 87.8%
4r9pA00 2.60.200.10 Mainly Beta › Sandwich › Tumour Suppressor Smad4 › 0.74 65.0 6.38e-01 99.5% 86.2%
3d33A00 2.60.40.3080 Mainly Beta › Sandwich › Immunoglobulin-like › 0.66 32.0 4.57e-01 97.0% 97.9%
2bv4A00 2.60.120.400 Mainly Beta › Sandwich › Jelly Rolls › Calcium-mediated lectin 0.55 30.0 3.91e-01 98.0% 92.0%
5jtwA05 2.60.40.1930 Mainly Beta › Sandwich › Immunoglobulin-like › Macroglobulin (MG2) domain 0.54 30.0 3.71e-01 71.6% 86.0%
1z0sA02 2.60.200.30 Mainly Beta › Sandwich › Tumour Suppressor Smad4 › Probable inorganic polyphosphate/atp-NAD kinase; domain 2 0.54 29.0 3.63e-01 78.2% 83.2%
2q3xA00 2.60.40.150 Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain 0.54 32.0 3.70e-01 93.4% 81.0%
1d2oA01 2.60.40.1140 Mainly Beta › Sandwich › Immunoglobulin-like › Collagen-binding surface protein Cna, B-type domain 0.53 24.0 3.08e-01 93.4% 71.0%
2e8yA04 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.52 25.0 3.39e-01 70.1% 92.2%
5f7uA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.52 29.0 3.71e-01 83.8% 95.5%
1jz7A04 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.52 28.0 3.68e-01 93.4% 96.2%
6se8A04 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.51 29.0 3.77e-01 70.6% 100.0%
3b2dC00 2.60.40.770 Mainly Beta › Sandwich › Immunoglobulin-like › 0.50 33.0 3.80e-01 98.5% 91.4%
ECOD (29)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2142307 73.1.1.6 ↗ beta sandwiches › SMAD/FHA domain › SMAD/FHA domain › SMAD/FHA domain › IRF-3 0.83 68.0 7.03e-01 100.0% 87.8%
3912381 73.1.1.6 ↗ beta sandwiches › SMAD/FHA domain › SMAD/FHA domain › SMAD/FHA domain › IRF-3 0.83 74.0 7.08e-01 100.0% 82.3%
3899206 73.1.1.6 ↗ beta sandwiches › SMAD/FHA domain › SMAD/FHA domain › SMAD/FHA domain › IRF-3 0.82 71.0 7.01e-01 100.0% 85.4%
3470623 73.1.1.6 ↗ beta sandwiches › SMAD/FHA domain › SMAD/FHA domain › SMAD/FHA domain › IRF-3 0.81 70.0 6.98e-01 99.0% 87.5%
3914798 73.1.1.6 ↗ beta sandwiches › SMAD/FHA domain › SMAD/FHA domain › SMAD/FHA domain › IRF-3 0.80 73.0 7.28e-01 99.5% 92.5%
3895000 73.1.1.6 ↗ beta sandwiches › SMAD/FHA domain › SMAD/FHA domain › SMAD/FHA domain › IRF-3 0.80 70.0 7.05e-01 100.0% 89.9%
3772155 73.1.1.6 ↗ beta sandwiches › SMAD/FHA domain › SMAD/FHA domain › SMAD/FHA domain › IRF-3 0.80 71.0 6.75e-01 100.0% 80.4%
3738478 73.1.1.1 ↗ beta sandwiches › SMAD/FHA domain › SMAD/FHA domain › SMAD/FHA domain › FHA 0.80 41.0 5.79e-01 92.4% 100.0%
169139 73.1.1.6 ↗ beta sandwiches › SMAD/FHA domain › SMAD/FHA domain › SMAD/FHA domain › IRF-3 0.79 73.0 6.76e-01 100.0% 79.2%
2722184 73.1.1.3 ↗ beta sandwiches › SMAD/FHA domain › SMAD/FHA domain › SMAD/FHA domain › MH2 0.79 66.0 6.92e-01 98.0% 94.4%
3270361 73.1.1.9 ↗ beta sandwiches › SMAD/FHA domain › SMAD/FHA domain › SMAD/FHA domain › FHA_2 0.79 44.0 5.82e-01 97.5% 98.2%
3887924 73.1.1.6 ↗ beta sandwiches › SMAD/FHA domain › SMAD/FHA domain › SMAD/FHA domain › IRF-3 0.79 71.0 7.04e-01 100.0% 90.2%
2069 73.1.1.6 ↗ beta sandwiches › SMAD/FHA domain › SMAD/FHA domain › SMAD/FHA domain › IRF-3 0.79 71.0 6.56e-01 100.0% 77.0%
3490466 73.1.1.6 ↗ beta sandwiches › SMAD/FHA domain › SMAD/FHA domain › SMAD/FHA domain › IRF-3 0.78 53.0 6.38e-01 76.1% 99.3%
3912511 73.1.1.3 ↗ beta sandwiches › SMAD/FHA domain › SMAD/FHA domain › SMAD/FHA domain › MH2 0.78 69.0 6.87e-01 100.0% 89.3%
3933647 73.1.1.3 ↗ beta sandwiches › SMAD/FHA domain › SMAD/FHA domain › SMAD/FHA domain › MH2 0.78 68.0 6.81e-01 99.5% 90.0%
3999204 73.1.1.3 ↗ beta sandwiches › SMAD/FHA domain › SMAD/FHA domain › SMAD/FHA domain › MH2 0.77 68.0 6.90e-01 99.5% 92.8%
3176235 73.1.1.1 ↗ beta sandwiches › SMAD/FHA domain › SMAD/FHA domain › SMAD/FHA domain › FHA 0.77 40.0 5.60e-01 95.4% 100.0%
3234709 73.1.1.3 ↗ beta sandwiches › SMAD/FHA domain › SMAD/FHA domain › SMAD/FHA domain › MH2 0.76 69.0 6.77e-01 100.0% 89.0%
3247678 73.1.1.3 ↗ beta sandwiches › SMAD/FHA domain › SMAD/FHA domain › SMAD/FHA domain › MH2 0.75 68.0 6.86e-01 99.5% 94.9%
3937000 73.1.1.3 ↗ beta sandwiches › SMAD/FHA domain › SMAD/FHA domain › SMAD/FHA domain › MH2 0.75 70.0 6.77e-01 99.0% 91.7%
3882303 73.1.1.1 ↗ beta sandwiches › SMAD/FHA domain › SMAD/FHA domain › SMAD/FHA domain › FHA 0.72 43.0 5.11e-01 98.0% 83.6%
3664663 73.1.1.0 ↗ beta sandwiches › SMAD/FHA domain › SMAD/FHA domain › SMAD/FHA domain 0.70 41.0 5.33e-01 92.4% 100.0%
3214802 73.1.1.3 ↗ beta sandwiches › SMAD/FHA domain › SMAD/FHA domain › SMAD/FHA domain › MH2 0.66 55.0 5.83e-01 98.0% 97.1%
3180245 73.1.1.0 ↗ beta sandwiches › SMAD/FHA domain › SMAD/FHA domain › SMAD/FHA domain 0.64 49.0 5.28e-01 99.5% 90.6%
3940218 3156.1.1.0 ↗ beta sandwiches › Cupredoxin-like › Cupredoxin-related › Cupredoxin-related 0.53 27.0 3.74e-01 97.5% 98.9%
4063161 10.32.1.0 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like 0.52 26.0 3.68e-01 93.9% 100.0%
5042218 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.52 25.0 3.55e-01 95.4% 95.8%
3760983 3335.1.1.3 ↗ beta barrels › Handle domain in transferrin-binding protein B › Handle domain in transferrin-binding protein B › Handle domain in transferrin-binding protein B › KCTD18_C 0.51 28.0 3.59e-01 97.0% 100.0%
D2 medium residues 92-200
PDB
Domain cluster: rep: N9-5__YP_010084611__Macaca_nemestrina_rhadinovirus_2__123630__D17-120
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00605.24 best IRF 39.0 1.20e-09 94.5% 96.2%