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vWFA_domain-containing_protein

Euk-Vir

Acanthamoeba_polyphaga_moumouvirus

vWFA_domain-containing_protein__YP_007354026__Acanthamoeba_polyphaga_moumouvirus__1269028

Identity

Accession:
YP_007354026 ↗
Protein ID:
vWFA_domain-containing_protein
Kingdom:
euk

Quality

49.8 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Megaviricetes› Imitervirales› Mimiviridae› Moumouvirus› Acanthamoeba_polyphaga_moumouvirus

TaxID: 1269028

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 7-249
PDB
Domain cluster: rep: aot2015-NO08_SRR1761682_USA_scaffold_2_curated_prodigal-single.1__X__X__00112__D438-482_516-700
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF25106.2 best VWA_4 35.6 9.70e-09 74.1% 98.8%
CATH (58)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4fx5A02 3.40.50.410 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain 0.81 59.0 6.84e-01 82.3% 98.9%
3gxbA00 3.40.50.410 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain 0.80 57.0 6.69e-01 82.3% 98.9%
4wfqA00 3.40.50.410 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain 0.80 61.0 6.81e-01 82.3% 97.4%
4cn8A02 3.40.50.410 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain 0.80 59.0 6.62e-01 82.3% 94.8%
1shuX00 3.40.50.410 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain 0.79 56.0 6.46e-01 82.7% 96.1%
6snkA01 3.40.50.410 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain 0.78 57.0 6.58e-01 82.3% 98.4%
3efoB04 3.40.50.410 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain 0.78 62.0 6.26e-01 81.5% 99.6%
7b7pA01 3.40.50.410 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain 0.78 63.0 6.13e-01 82.7% 98.1%
1atzB00 3.40.50.410 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain 0.78 58.0 6.55e-01 82.7% 97.4%
1m2vB04 3.40.50.410 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain 0.78 62.0 6.36e-01 81.9% 99.2%
2nutA03 3.40.50.410 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain 0.77 62.0 6.15e-01 82.3% 99.2%
1aoxA00 3.40.50.410 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain 0.77 59.0 6.55e-01 82.7% 95.5%
3fcsB03 3.40.50.410 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain 0.76 61.0 6.16e-01 82.3% 98.8%
2iueA00 3.40.50.410 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain 0.76 61.0 6.54e-01 82.7% 98.1%
7zs9401 3.40.50.410 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain 0.75 59.0 6.18e-01 80.2% 100.0%
2nutB04 3.40.50.410 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain 0.74 60.0 6.11e-01 82.3% 99.6%
4f1jA00 3.40.50.410 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain 0.74 57.0 6.28e-01 82.3% 95.0%
2kpoA00 3.40.50.11230 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.74 33.0 4.98e-01 82.7% 94.5%
2lciA00 3.40.50.11230 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.68 37.0 4.89e-01 82.3% 94.8%
2l69A00 3.40.50.11230 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.67 37.0 4.76e-01 82.3% 94.0%
1akqA00 3.40.50.360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain 0.67 41.0 5.17e-01 81.5% 100.0%
1c2yA00 3.40.50.960 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Lumazine/riboflavin synthase 0.62 36.0 4.38e-01 82.3% 87.7%
2bd0A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.59 48.0 4.97e-01 85.6% 100.0%
1v2dA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.58 40.0 4.12e-01 99.2% 71.9%
2cw5C01 3.40.50.10790 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal 0.58 37.0 4.50e-01 95.1% 100.0%
1ydmB00 3.40.50.10420 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NagB/RpiA/CoA transferase-like 0.58 35.0 4.04e-01 89.3% 79.1%
5ksoA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 37.0 4.39e-01 82.3% 94.6%
3v1tC01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.57 34.0 4.06e-01 86.4% 84.7%
5a62A00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.56 45.0 4.32e-01 81.9% 91.2%
4ac9C01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.56 39.0 4.45e-01 82.7% 93.4%
3qitB00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.56 44.0 4.17e-01 81.1% 91.2%
1fduB00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.56 46.0 4.41e-01 86.4% 90.4%
7wkqB01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.55 44.0 4.78e-01 99.2% 100.0%
3u49D00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.55 45.0 4.60e-01 86.4% 97.5%
2qq5A00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.55 45.0 4.59e-01 86.4% 96.6%
8eh2A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.55 45.0 4.49e-01 86.0% 93.6%
2fwmX00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.55 45.0 4.75e-01 100.0% 98.1%
3p19B00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 45.0 4.70e-01 86.0% 98.2%
5er6C00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 45.0 4.57e-01 86.0% 95.4%
4jfcA01 3.90.226.10 Alpha Beta › Alpha-Beta Complex › 2-enoyl-CoA Hydratase; Chain A, domain 1 › 2-enoyl-CoA Hydratase; Chain A, domain 1 0.54 39.0 4.29e-01 97.9% 89.1%
4wczC01 3.90.226.10 Alpha Beta › Alpha-Beta Complex › 2-enoyl-CoA Hydratase; Chain A, domain 1 › 2-enoyl-CoA Hydratase; Chain A, domain 1 0.54 38.0 4.22e-01 100.0% 88.3%
3gvcA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 45.0 4.50e-01 86.0% 96.3%
4dqxB00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 44.0 4.45e-01 86.0% 95.6%
4gkbA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 45.0 4.48e-01 86.4% 93.9%
4b45A01 3.40.50.1440 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Tubulin/FtsZ, GTPase domain 0.54 45.0 4.82e-01 99.6% 100.0%
2x7jA01 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.54 37.0 4.06e-01 81.9% 85.6%
2dtxA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 44.0 4.37e-01 86.4% 92.9%
4wnyA00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.53 29.0 3.84e-01 77.4% 96.2%
1f21A00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.53 29.0 3.57e-01 77.4% 82.9%
1sulB00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 36.0 4.02e-01 82.7% 89.2%
1fuyB01 3.40.50.1100 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.51 30.0 3.57e-01 74.1% 83.5%
2qyaA01 3.30.1860.10 Alpha Beta › 2-Layer Sandwich › uncharacterized conserved protein from methanopyrus kandleri fold like › uncharacterized conserved protein from methanopyrus kandleri domain like 0.51 22.0 3.18e-01 87.2% 87.9%
4xc6B01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.50 40.0 3.97e-01 82.3% 82.0%
3s55E00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.50 46.0 4.52e-01 99.6% 98.1%
2qtlA03 3.40.50.80 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module 0.50 32.0 3.90e-01 74.1% 99.4%
8einA01 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.50 42.0 4.00e-01 87.7% 89.8%
3k7yA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.50 38.0 3.73e-01 78.6% 71.2%
4ospD00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.50 45.0 4.59e-01 99.2% 97.1%
ECOD (95)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3191387 2006.1.6.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.84 82.0 7.31e-01 100.0% 93.1%
3927340 2006.1.6.33 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA_4 0.84 63.0 7.03e-01 81.1% 94.4%
3579644 2006.1.6.33 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA_4 0.84 61.0 6.82e-01 82.7% 91.8%
5028967 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.83 61.0 6.93e-01 82.7% 95.3%
5062017 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.82 60.0 6.95e-01 82.3% 98.4%
3227078 2006.1.6.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.82 61.0 6.97e-01 81.1% 98.9%
3214871 2006.1.6.33 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA_4 0.82 61.0 7.04e-01 80.2% 100.0%
3935806 2006.1.6.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.81 63.0 7.01e-01 100.0% 96.5%
3187631 2006.1.6.33 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA_4 0.81 65.0 6.17e-01 82.3% 91.8%
5011082 2006.1.6.13 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA_3 0.81 54.0 5.93e-01 79.8% 80.0%
3500876 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.81 58.0 6.61e-01 82.7% 95.6%
4945636 2006.1.6.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.81 63.0 6.96e-01 82.3% 96.5%
4384064 2006.1.6.33 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA_4 0.81 61.0 6.41e-01 82.7% 83.6%
3227080 2006.1.6.33 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA_4 0.81 61.0 6.70e-01 83.1% 93.0%
3235648 2006.1.6.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.81 62.0 6.99e-01 81.5% 98.5%
3255134 2006.1.6.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.80 65.0 6.80e-01 82.7% 92.7%
4936416 2006.1.6.12 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA_2 0.80 61.0 6.16e-01 82.7% 77.8%
4975173 2006.1.6.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.80 59.0 6.65e-01 82.3% 94.8%
4010065 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.80 59.0 6.70e-01 82.3% 97.8%
4985340 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.80 56.0 6.65e-01 82.3% 99.4%
3930961 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.80 58.0 6.50e-01 82.3% 93.7%
4927526 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.80 56.0 5.78e-01 82.3% 74.4%
3929334 2006.1.6.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.80 55.0 6.03e-01 81.9% 83.3%
3266779 2006.1.6.33 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA_4 0.79 68.0 6.82e-01 100.0% 87.3%
5082008 2006.1.6.12 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA_2 0.79 60.0 6.70e-01 82.7% 95.9%
3242647 2006.1.6.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.79 62.0 6.89e-01 80.7% 97.5%
4969900 2006.1.6.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.79 56.0 6.54e-01 81.1% 98.3%
3935808 2006.1.6.33 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA_4 0.79 60.0 6.72e-01 80.2% 97.9%
3661688 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.79 60.0 6.57e-01 84.8% 92.2%
5057273 2006.1.6.12 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA_2 0.79 56.0 6.41e-01 82.7% 94.1%
4141558 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.79 59.0 6.62e-01 82.3% 96.3%
3779727 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.79 60.0 6.72e-01 99.2% 96.9%
3249751 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.79 73.0 7.01e-01 96.7% 97.0%
5052615 2006.1.6.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.79 59.0 6.32e-01 81.9% 88.1%
5083686 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.79 60.0 6.62e-01 89.3% 94.5%
3620957 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.78 56.0 6.27e-01 82.7% 91.6%
3599511 2006.1.6.12 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA_2 0.78 61.0 6.07e-01 84.0% 76.5%
4015689 2006.1.6.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.78 63.0 6.46e-01 82.7% 96.6%
3178437 2006.1.6.7 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › Sec23_trunk 0.78 63.0 6.30e-01 82.7% 95.6%
3579093 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.78 57.0 6.34e-01 82.7% 92.3%
3855818 2006.1.6.7 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › Sec23_trunk 0.78 63.0 6.24e-01 82.3% 98.4%
3590921 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.78 63.0 6.12e-01 83.1% 94.3%
3934768 2006.1.6.33 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA_4 0.78 61.0 6.61e-01 82.7% 93.3%
3272537 2006.1.6.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.78 62.0 6.24e-01 81.5% 100.0%
3930561 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.78 54.0 6.15e-01 82.3% 91.9%
3488216 2006.1.6.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.78 53.0 6.08e-01 100.0% 92.2%
3925074 2006.1.6.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.78 59.0 6.68e-01 81.5% 100.0%
4944900 2006.1.6.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.78 53.0 5.70e-01 73.3% 78.6%
3529481 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.77 58.0 6.59e-01 84.4% 97.9%
3263364 2006.1.6.12 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA_2 0.77 67.0 7.03e-01 99.6% 98.2%
3612621 2006.1.6.7 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › Sec23_trunk 0.77 63.0 5.95e-01 82.7% 97.5%
5079558 2006.1.6.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.77 58.0 6.64e-01 81.5% 100.0%
4971996 2006.1.6.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.77 60.0 6.46e-01 82.3% 91.9%
3707625 2006.1.6.7 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › Sec23_trunk 0.77 63.0 5.93e-01 82.7% 98.2%
3236791 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.77 52.0 6.14e-01 82.3% 97.0%
3232631 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.77 54.0 5.85e-01 82.3% 83.4%
3302952 2006.1.6.7 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › Sec23_trunk 0.77 62.0 6.14e-01 81.9% 98.8%
2531242 2006.1.6.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.77 61.0 5.07e-01 81.5% 59.5%
3972821 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.77 65.0 6.35e-01 86.8% 90.8%
3927887 2006.1.6.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.77 55.0 6.31e-01 82.7% 95.7%
4992063 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.77 51.0 5.29e-01 79.4% 71.6%
None — 0.77 62.0 6.51e-01 84.8% 90.9%
4874143 2006.1.6.2 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › Integrin_beta 0.77 61.0 6.13e-01 82.3% 96.8%
3242671 2006.1.6.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.77 63.0 6.70e-01 100.0% 95.3%
3936405 2006.1.6.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.76 61.0 6.58e-01 81.9% 96.7%
3784226 2006.1.6.7 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › Sec23_trunk 0.76 62.0 6.02e-01 82.3% 98.1%
3999802 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.76 56.0 6.32e-01 82.7% 95.8%
4983536 2006.1.6.12 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA_2 0.76 61.0 6.23e-01 82.7% 93.8%
3933625 2006.1.6.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.76 55.0 5.96e-01 82.3% 85.2%
3472668 2006.1.6.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.76 61.0 6.62e-01 100.0% 96.2%
3222994 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.76 53.0 6.04e-01 73.7% 92.4%
5041045 2006.1.6.12 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA_2 0.76 56.0 6.39e-01 92.2% 96.8%
5049407 2006.1.6.12 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA_2 0.76 61.0 6.61e-01 81.9% 99.0%
3576586 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.75 55.0 6.29e-01 82.7% 97.8%
3927338 2006.1.6.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.75 66.0 5.47e-01 90.5% 91.9%
3238254 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.75 54.0 4.66e-01 82.3% 49.6%
4020448 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.75 59.0 6.24e-01 84.8% 90.2%
4941072 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.75 60.0 6.35e-01 82.3% 94.5%
3925073 2006.1.6.49 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › PF28725 0.74 51.0 5.95e-01 82.7% 96.6%
3440234 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.73 63.0 6.42e-01 100.0% 91.5%
3933150 2006.1.6.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.73 63.0 6.47e-01 100.0% 93.9%
3262787 2006.1.6.14 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › vWA-TerF-like 0.72 54.0 5.93e-01 83.5% 92.0%
5057179 2006.1.6.12 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA_2 0.72 46.0 5.69e-01 81.1% 99.4%
4958321 2006.1.6.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.72 50.0 5.85e-01 84.4% 97.7%
5051874 2006.1.6.15 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › DUF58 0.71 57.0 6.06e-01 82.7% 92.2%
3969876 2006.1.6.15 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › DUF58 0.69 56.0 5.79e-01 82.7% 88.6%
3936045 2006.1.6.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.69 52.0 5.87e-01 81.9% 100.0%
3523981 2006.1.6.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.69 52.0 5.71e-01 85.6% 93.0%
5018603 2006.1.6.15 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › DUF58 0.68 54.0 5.62e-01 81.5% 92.5%
3204752 2006.1.6.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.68 54.0 5.65e-01 82.3% 92.4%
3958774 2006.1.6.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.67 54.0 5.16e-01 83.1% 77.7%
3414378 2006.1.6.32 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › vWA_Ro60 0.65 48.0 5.37e-01 83.1% 96.8%
3940941 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.64 59.0 3.50e-01 98.4% 26.4%
3978017 11.1.5.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f 0.63 60.0 4.66e-01 98.8% 67.2%
5008584 2486.1.1.1 ↗ a/b three-layered sandwiches › ClpP/crotonase › ClpP/crotonase › ClpP/crotonase › ECH_1 0.56 38.0 3.84e-01 100.0% 66.3%
D2 high residues 891-944
PDB
Domain cluster: representative
Pfam (3)
AccessionNameScoreE-valueQ covHMM cov
PF22191.3 best IBR_1 42.5 6.90e-11 87.0% 72.3%
PF01485.28 IBR 35.9 9.10e-09 79.6% 60.0%
PF22605.3 IBR_2 30.8 3.60e-07 77.8% 69.4%
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
7ylsB01 2.102.10.10 Mainly Beta › 3-layer Sandwich › Rieske Iron-sulfur Protein › Rieske [2Fe-2S] iron-sulphur domain 0.65 46.0 3.78e-01 77.8% 50.9%
2k4jA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.58 41.0 3.39e-01 75.9% 93.3%
1xezA02 2.70.240.20 Mainly Beta › Distorted Sandwich › Leukocidin-like › Leukocidin/Hemolysin toxin, cytolysin domain 0.55 46.0 2.80e-01 100.0% 19.3%
1p2fA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 34.0 2.95e-01 70.4% 80.0%
4chdA00 3.30.70.3510 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.50 34.0 2.61e-01 72.2% 61.5%
ECOD (73)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3626404 376.1.4.1 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › Ariadne-1 protein homolog › IBR 0.97 91.0 8.19e-01 100.0% 75.7%
3581878 376.1.6.1 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR 0.97 84.0 7.80e-01 92.6% 75.4%
3724438 376.1.4.2 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › Ariadne-1 protein homolog › IBR_1 0.95 84.0 7.85e-01 100.0% 78.5%
3193124 376.1.6.1 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR 0.93 63.0 4.42e-01 72.2% 25.5%
3808540 376.1.6.9 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › PF26200 0.91 76.0 5.32e-01 100.0% 32.0%
3467249 376.1.4.4 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › Ariadne-1 protein homolog › PF26200 0.89 73.0 6.80e-01 100.0% 72.3%
3728976 376.1.6.2 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR_1 0.88 74.0 6.74e-01 98.1% 70.0%
3904473 376.1.6.1 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR 0.88 68.0 4.86e-01 88.9% 31.4%
3893608 376.1.6.2 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR_1 0.88 61.0 5.57e-01 90.7% 57.4%
3919958 376.1.6.2 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR_1 0.88 64.0 6.63e-01 94.4% 82.0%
3259912 376.1.4.2 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › Ariadne-1 protein homolog › IBR_1 0.87 65.0 5.57e-01 100.0% 52.5%
3933458 376.1.4.3 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › Ariadne-1 protein homolog › IBR_2 0.87 67.0 6.71e-01 100.0% 80.0%
4920192 611.8.1.11 ↗ alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › Ariadne, IBR_1 0.87 60.0 4.52e-01 90.7% 32.5%
3314132 376.1.6.10 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR, PF26200 0.87 76.0 5.37e-01 100.0% 34.0%
3878932 376.1.4.2 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › Ariadne-1 protein homolog › IBR_1 0.85 60.0 5.82e-01 92.6% 66.7%
3226800 376.1.4.3 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › Ariadne-1 protein homolog › IBR_2 0.85 67.0 6.43e-01 100.0% 75.0%
3633967 376.1.6.9 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › PF26200 0.85 78.0 6.60e-01 100.0% 63.5%
5047273 375.1.1.0 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.85 57.0 6.44e-01 75.9% 95.0%
3566936 376.1.4.2 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › Ariadne-1 protein homolog › IBR_1 0.84 75.0 7.00e-01 100.0% 80.0%
3197309 376.1.4.4 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › Ariadne-1 protein homolog › PF26200 0.84 77.0 5.95e-01 100.0% 49.1%
3867678 376.1.4.4 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › Ariadne-1 protein homolog › PF26200 0.83 77.0 7.17e-01 100.0% 83.1%
3584026 376.1.6.11 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR, IBR_1 0.83 76.0 5.29e-01 100.0% 34.4%
3748079 376.1.6.10 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR, PF26200 0.83 76.0 5.32e-01 100.0% 34.8%
3784620 376.1.4.2 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › Ariadne-1 protein homolog › IBR_1 0.83 73.0 7.31e-01 100.0% 94.5%
3261059 376.1.6.2 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR_1 0.82 64.0 5.69e-01 100.0% 60.0%
3937591 376.1.4.2 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › Ariadne-1 protein homolog › IBR_1 0.82 66.0 6.58e-01 100.0% 83.6%
3780291 376.1.6.1 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR 0.82 66.0 6.04e-01 100.0% 67.1%
3226770 376.1.4.0 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › Ariadne-1 protein homolog 0.82 58.0 6.51e-01 74.1% 100.0%
3846875 376.1.4.2 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › Ariadne-1 protein homolog › IBR_1 0.82 64.0 6.06e-01 100.0% 70.8%
3784601 376.1.6.1 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR 0.82 62.0 6.71e-01 96.3% 97.8%
4022423 376.1.6.7 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR_2 0.82 74.0 6.46e-01 100.0% 72.5%
3242627 376.1.4.2 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › Ariadne-1 protein homolog › IBR_1 0.82 70.0 6.07e-01 100.0% 62.5%
3585112 376.1.6.2 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR_1 0.81 70.0 6.54e-01 100.0% 76.9%
3537482 376.1.4.2 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › Ariadne-1 protein homolog › IBR_1 0.80 64.0 6.61e-01 90.7% 92.0%
3998754 376.1.6.1 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR 0.79 70.0 6.56e-01 96.3% 78.5%
3266250 376.1.6.1 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR 0.79 62.0 6.02e-01 100.0% 76.7%
3786601 375.1.1.200 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › zf-LSD1 0.79 48.0 5.70e-01 92.6% 94.3%
3873719 376.1.4.2 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › Ariadne-1 protein homolog › IBR_1 0.78 66.0 6.35e-01 100.0% 81.7%
3733157 376.1.6.1 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR 0.78 61.0 5.47e-01 100.0% 61.3%
5029687 375.1.1.0 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.78 55.0 5.92e-01 74.1% 97.8%
3846254 376.1.6.1 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR 0.78 60.0 5.10e-01 100.0% 51.1%
3897593 376.1.6.2 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR_1 0.78 67.0 5.79e-01 100.0% 62.5%
3748179 376.1.6.1 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR 0.77 71.0 5.90e-01 100.0% 66.7%
4015303 376.1.6.1 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR 0.77 65.0 6.47e-01 100.0% 90.9%
3591420 375.1.1.0 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.77 59.0 6.36e-01 85.2% 100.0%
3873729 376.1.4.1 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › Ariadne-1 protein homolog › IBR 0.76 64.0 5.86e-01 100.0% 71.4%
3686965 376.1.6.1 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR 0.76 63.0 6.31e-01 100.0% 89.1%
4881936 376.1.4.1 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › Ariadne-1 protein homolog › IBR 0.76 64.0 5.76e-01 90.7% 72.2%
3731757 376.1.4.1 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › Ariadne-1 protein homolog › IBR 0.76 56.0 6.04e-01 88.9% 95.6%
3559327 376.1.4.2 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › Ariadne-1 protein homolog › IBR_1 0.76 66.0 5.48e-01 100.0% 56.7%
3907479 376.1.6.0 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain 0.76 69.0 6.14e-01 100.0% 80.0%
3358914 376.1.6.1 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR 0.76 64.0 5.86e-01 100.0% 71.4%
3816261 376.1.6.1 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR 0.75 63.0 5.67e-01 100.0% 66.7%
5047885 375.1.1.0 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.75 50.0 5.43e-01 85.2% 84.4%
3891437 376.1.6.1 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR 0.74 61.0 6.15e-01 100.0% 90.9%
8105 376.1.6.2 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR_1 0.73 56.0 5.13e-01 100.0% 63.0%
3734604 376.1.6.1 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR 0.73 56.0 5.48e-01 100.0% 75.0%
3907697 376.1.4.2 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › Ariadne-1 protein homolog › IBR_1 0.73 67.0 5.93e-01 100.0% 73.3%
3247805 376.1.6.1 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR 0.73 55.0 5.72e-01 100.0% 90.0%
3634472 376.1.6.1 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR 0.73 58.0 5.51e-01 100.0% 73.8%
4018431 376.1.4.1 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › Ariadne-1 protein homolog › IBR 0.72 57.0 5.68e-01 100.0% 85.5%
3238220 376.1.6.1 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR 0.72 61.0 5.76e-01 100.0% 76.9%
3437513 376.1.4.1 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › Ariadne-1 protein homolog › IBR 0.72 66.0 6.16e-01 100.0% 90.8%
3112469 376.1.6.0 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain 0.71 56.0 5.18e-01 98.1% 66.7%
3748180 376.1.6.0 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain 0.71 56.0 5.82e-01 100.0% 96.0%
4978165 2484.1.1.124 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 0.71 48.0 3.22e-01 70.4% 20.5%
4979574 2484.1.1.302 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB 0.71 48.0 3.35e-01 70.4% 24.1%
5017725 2484.1.1.302 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB 0.71 48.0 3.24e-01 70.4% 20.5%
3723241 376.1.6.1 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR 0.71 60.0 5.80e-01 100.0% 85.0%
3207082 376.1.4.1 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › Ariadne-1 protein homolog › IBR 0.66 59.0 5.86e-01 100.0% 98.2%
4933539 2484.1.1.302 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB 0.65 50.0 3.32e-01 85.2% 28.4%
3507653 375.4.1.0 ↗ few secondary structure elements › Rubredoxin-like › Nucleolar RNA-binding protein Nop10-like › Nucleolar RNA-binding protein Nop10-like 0.60 51.0 3.61e-01 94.4% 86.5%
4028249 330.3.1.0 ↗ a+b two layers › dsRBD-like › Peptidyl-tRNA hydrolase domain-like › Peptidyl-tRNA hydrolase domain-like 0.56 38.0 3.82e-01 72.2% 77.8%
D3 medium residues 261-365
PDB
D4 medium residues 366-459
PDB