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viral_innexin-c3.1
Euk-VirIchnoviriform_fugitivi
viral_innexin-c3.1__YP_001031272__Ichnoviriform_fugitivi__265522
Identity
- Accession:
- YP_001031272 ↗
- Protein ID:
- viral_innexin-c3.1
- Kingdom:
- euk
Quality
79.2
mean pLDDT
Cluster
View cluster (13 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 17-66_118-136_207-221_265-278
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00876.24 best | Innexin | 32.6 | 7.20e-08 | 46.9% | 11.7% |
CATH (2)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3u9jA00 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.55 | 44.0 | 3.74e-01 | 85.7% | 59.2% |
| 2vzoA03 | 3.20.20.80 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases | 0.50 | 35.0 | 2.38e-01 | 100.0% | 20.6% |
ECOD (19)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3414363 | 3937.1.1.2 ↗ | alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin | 0.91 | 87.0 | 5.64e-01 | 100.0% | 74.9% |
| 3626086 | 3937.1.1.2 ↗ | alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin | 0.89 | 85.0 | 5.48e-01 | 100.0% | 74.4% |
| 4001691 | 3937.1.1.2 ↗ | alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin | 0.88 | 84.0 | 5.92e-01 | 100.0% | 81.2% |
| 3211111 | 3937.1.1.2 ↗ | alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin | 0.88 | 83.0 | 5.40e-01 | 100.0% | 71.7% |
| 3234312 | 3937.1.1.2 ↗ | alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin | 0.88 | 83.0 | 5.40e-01 | 100.0% | 72.2% |
| 3222904 | 3937.1.1.2 ↗ | alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin | 0.88 | 84.0 | 5.36e-01 | 100.0% | 71.8% |
| 3583608 | 3937.1.1.2 ↗ | alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin | 0.88 | 71.0 | 5.23e-01 | 84.7% | 95.2% |
| 3231554 | 3937.1.1.2 ↗ | alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin | 0.86 | 82.0 | 5.40e-01 | 100.0% | 76.0% |
| 3485099 | 3937.1.1.2 ↗ | alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin | 0.83 | 69.0 | 5.03e-01 | 87.8% | 92.7% |
| 3518544 | 5069.1.3.80 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › Innexin | 0.73 | 57.0 | 4.62e-01 | 81.6% | 87.6% |
| 3781132 | 3755.4.1.48 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › V_ATPase_I | 0.61 | 42.0 | 3.63e-01 | 70.4% | 82.7% |
| 3999537 | 3324.1.1.2 ↗ | extended segments › Helical arch in Ski2-like helicases › Helical arch in Ski2-like helicases › Helical arch in Ski2-like helicases | 0.60 | 41.0 | 3.67e-01 | 70.4% | 60.7% |
| 3416428 | 633.6.1.8 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACOX_C_alpha1 | 0.59 | 51.0 | 4.19e-01 | 94.9% | 84.4% |
| 4028549 | 5059.1.1.17 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › TMEM234 | 0.59 | 35.0 | 3.32e-01 | 95.9% | 50.4% |
| 3980443 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.58 | 40.0 | 3.78e-01 | 95.9% | 60.0% |
| 1883738 | 633.6.1.8 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACOX_C_alpha1 | 0.57 | 49.0 | 4.02e-01 | 94.9% | 80.0% |
| 3616792 | 633.6.1.8 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACOX_C_alpha1 | 0.55 | 49.0 | 3.86e-01 | 96.9% | 79.5% |
| 1714462 | 1021.1.1.0 ↗ | a+b two layers › C-terminal domain in RNA helicases › C-terminal domain in RNA helicases › C-terminal domain in RNA helicases | 0.55 | 37.0 | 3.90e-01 | 70.4% | 76.4% |
| 4025459 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.53 | 36.0 | 3.57e-01 | 94.9% | 67.0% |
D2
medium
residues 67-80_102-117_222-264
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00876.24 best | Innexin | 39.4 | 5.90e-10 | 60.3% | 12.0% |
CATH (14)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1c3gA01 | 2.60.260.20 | Mainly Beta › Sandwich › HSP40/DNAj peptide-binding domain › Urease metallochaperone UreE, N-terminal domain | 0.65 | 39.0 | 3.85e-01 | 100.0% | 56.4% |
| 4gs3A00 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.61 | 37.0 | 3.44e-01 | 94.5% | 48.9% |
| 4k3bA02 | 3.10.20.310 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac | 0.60 | 33.0 | 3.18e-01 | 83.6% | 46.4% |
| 2py5A05 | 4.10.80.20 | Few Secondary Structures › Irregular › Rhinovirus 14, subunit 4 › DNA polymerase; domain 5 | 0.59 | 27.0 | 3.63e-01 | 86.3% | 93.3% |
| 1ue6D00 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.59 | 36.0 | 3.18e-01 | 95.9% | 42.3% |
| 5odnC00 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.57 | 35.0 | 3.17e-01 | 95.9% | 44.1% |
| 6j09A02 | 3.10.20.310 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac | 0.56 | 32.0 | 3.16e-01 | 82.2% | 51.3% |
| 1n7vA01 | 2.105.10.10 | Mainly Beta › 3 Propeller › Pseudo beta propeller › Pseudo beta propeller | 0.54 | 39.0 | 2.98e-01 | 76.7% | 81.9% |
| 3d2lA02 | 2.20.25.110 | Mainly Beta › Single Sheet › N-terminal domain of TfIIb › S-adenosyl-L-methionine-dependent methyltransferases | 0.54 | 36.0 | 3.90e-01 | 93.2% | 81.0% |
| 5w8mA00 | 3.60.21.10 | Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › Metallo-dependent phosphatases | 0.52 | 42.0 | 3.16e-01 | 91.8% | 95.9% |
| 2d42A02 | 3.10.450.380 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.52 | 39.0 | 4.12e-01 | 100.0% | 90.8% |
| 2qdfA02 | 3.10.20.310 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac | 0.52 | 32.0 | 3.07e-01 | 91.8% | 53.0% |
| 4n4bA00 | 2.115.10.20 | Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 | 0.51 | 42.0 | 2.83e-01 | 95.9% | 96.9% |
| 2ebfX01 | 3.10.670.10 | Alpha Beta › Roll › Secreted effector protein ssei fold › Secreted effector protein ssei. | 0.50 | 37.0 | 2.73e-01 | 78.1% | 71.5% |
ECOD (29)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3391149 | 3937.1.1.2 ↗ | alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin | 0.93 | 89.0 | 5.48e-01 | 100.0% | 55.8% |
| 3414363 | 3937.1.1.2 ↗ | alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin | 0.91 | 88.0 | 5.32e-01 | 100.0% | 57.6% |
| 3389084 | 3937.1.1.2 ↗ | alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin | 0.88 | 85.0 | 5.27e-01 | 100.0% | 53.6% |
| 3211111 | 3937.1.1.2 ↗ | alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin | 0.82 | 78.0 | 4.75e-01 | 100.0% | 52.5% |
| 3229557 | 3937.1.1.2 ↗ | alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin | 0.81 | 77.0 | 4.68e-01 | 100.0% | 54.0% |
| 3472642 | 3937.1.1.2 ↗ | alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin | 0.81 | 77.0 | 4.63e-01 | 100.0% | 55.8% |
| 3225873 | 3937.1.1.2 ↗ | alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin | 0.81 | 76.0 | 4.69e-01 | 100.0% | 52.7% |
| 3589882 | 4325.1.1.7 ↗ | mixed a+b and a/b › YegP-like › YegP-like › YegP-like › Arm-DNA-bind_4 | 0.69 | 35.0 | 4.14e-01 | 94.5% | 72.0% |
| 4641382 | 4099.1.1.32 ↗ | a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like › PF30019 | 0.64 | 37.0 | 2.82e-01 | 94.5% | 25.5% |
| 4299507 | 3256.1.1.2 ↗ | a+b two layers › DUF2233 N-terminal domain › DUF2233 N-terminal domain › DUF2233 N-terminal domain › eIF3g | 0.63 | 32.0 | 4.04e-01 | 87.7% | 94.3% |
| 3608304 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.63 | 34.0 | 2.96e-01 | 87.7% | 33.6% |
| 4034091 | 4325.1.1.7 ↗ | mixed a+b and a/b › YegP-like › YegP-like › YegP-like › Arm-DNA-bind_4 | 0.60 | 33.0 | 3.75e-01 | 90.4% | 74.0% |
| 3688597 | 2011.2.1.0 ↗ | a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Peptidyl-tRNA hydrolase-like › Peptidyl-tRNA hydrolase-like | 0.59 | 34.0 | 2.57e-01 | 93.2% | 21.8% |
| 4115098 | 3121.1.1.1 ↗ | a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA | 0.58 | 32.0 | 3.10e-01 | 82.2% | 45.9% |
| 3395022 | 394.1.1.1 ↗ | few secondary structure elements › Invertebrate chitin-binding proteins › Invertebrate chitin-binding proteins › Invertebrate chitin-binding proteins › CBM_14 | 0.56 | 38.0 | 3.83e-01 | 94.5% | 69.9% |
| 4887533 | 3121.1.1.1 ↗ | a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA | 0.54 | 32.0 | 2.89e-01 | 86.3% | 41.3% |
| 4943678 | 4178.1.1.0 ↗ | beta sandwiches › Putative glucosidase YicI, C-terminal domain › Putative glucosidase YicI, C-terminal domain › Putative glucosidase YicI, C-terminal domain | 0.54 | 32.0 | 3.09e-01 | 84.9% | 49.4% |
| 3173410 | 2004.1.1.19 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras | 0.53 | 33.0 | 2.36e-01 | 94.5% | 20.0% |
| 3999124 | 11.1.1.1 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Cadherin | 0.52 | 39.0 | 4.21e-01 | 98.6% | 98.3% |
| 4881206 | 3121.1.1.1 ↗ | a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA | 0.52 | 31.0 | 3.01e-01 | 86.3% | 50.6% |
| 4996027 | 304.139.1.2 ↗ | a+b two layers › Alpha-beta plaits › Cas7-related › CRISPR-associated protein Cas7/Csa2-related › RAMPs | 0.52 | 45.0 | 3.12e-01 | 98.6% | 96.2% |
| 4233683 | 171.1.1.1 ↗ | alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonuclease_3 | 0.51 | 35.0 | 2.48e-01 | 71.2% | 52.3% |
| 3573769 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.51 | 40.0 | 3.16e-01 | 86.3% | 62.5% |
| 4134015 | 101.1.8.1 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase | 0.51 | 38.0 | 3.03e-01 | 97.3% | 38.1% |
| 3402677 | 394.1.1.1 ↗ | few secondary structure elements › Invertebrate chitin-binding proteins › Invertebrate chitin-binding proteins › Invertebrate chitin-binding proteins › CBM_14 | 0.51 | 34.0 | 3.65e-01 | 93.2% | 86.2% |
| 3320817 | 2004.1.1.174 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Elong_Iki1 | 0.51 | 44.0 | 2.93e-01 | 95.9% | 91.0% |
| 3451388 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.51 | 44.0 | 2.99e-01 | 98.6% | 96.4% |
| 4898995 | 3121.1.1.1 ↗ | a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA | 0.50 | 31.0 | 2.89e-01 | 86.3% | 47.8% |
| 4399128 | 7581.1.1.30 ↗ | a/b three-layered sandwiches › Thiolase-like › Thiolase-like › Thiolase-like › Thiolase_N, ketoacyl-synt, Thiolase_C | 0.50 | 45.0 | 2.85e-01 | 100.0% | 87.3% |
D3
medium
residues 137-206_279-357
Domain cluster:
rep: viral_innexin-b10.1__YP_001031255__Ichnoviriform_fugitivi__265522__D133-179_273-358
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00876.24 best | Innexin | 43.1 | 4.60e-11 | 51.7% | 21.9% |
| PF00876.24 | Innexin | 39.8 | 4.40e-10 | 48.3% | 20.7% |
CATH (6)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2w31A00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.59 | 31.0 | 3.15e-01 | 83.9% | 48.0% |
| 6xz3A01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.57 | 35.0 | 3.88e-01 | 87.2% | 77.8% |
| 4irlB02 | 1.10.533.10 | Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas | 0.55 | 27.0 | 3.27e-01 | 87.2% | 71.0% |
| 1wdzA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.53 | 37.0 | 3.19e-01 | 71.1% | 81.4% |
| 1s35A01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 32.0 | 3.69e-01 | 91.9% | 88.1% |
| 5b2nA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.50 | 38.0 | 3.15e-01 | 79.2% | 78.7% |
ECOD (7)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3391149 | 3937.1.1.2 ↗ | alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin | 0.96 | 93.0 | 6.71e-01 | 99.3% | 62.0% |
| 3389084 | 3937.1.1.2 ↗ | alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin | 0.95 | 92.0 | 6.79e-01 | 100.0% | 67.3% |
| 4998835 | 3883.1.1.1 ↗ | alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf | 0.56 | 33.0 | 3.12e-01 | 85.9% | 46.9% |
| 4281985 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.56 | 36.0 | 3.72e-01 | 83.2% | 67.9% |
| 3712573 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.54 | 34.0 | 3.53e-01 | 81.9% | 65.7% |
| 3760698 | 192.2.1.53 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › PF31016 | 0.54 | 35.0 | 3.66e-01 | 83.2% | 70.4% |
| 3545963 | 3291.1.1.85 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PF31016 | 0.54 | 34.0 | 3.62e-01 | 83.2% | 69.6% |