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viral_innexin-g1.1

Euk-Vir

Ichnoviriform_fugitivi

viral_innexin-g1.1__YP_001031350__Ichnoviriform_fugitivi__265522

Identity

Accession:: YP_001031350 ↗
Protein ID:: viral_innexin-g1.1
Kingdom:: euk

Quality

86.2 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 25-111

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00876.24 best	Innexin	81.3	1.10e-22	100.0%	28.2%

ECOD (13)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3391149	3937.1.1.2 ↗	alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin	0.82	78.0	4.96e-01	100.0%	27.3%
3414363	3937.1.1.2 ↗	alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin	0.76	71.0	4.52e-01	100.0%	26.5%
3485099	3937.1.1.2 ↗	alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin	0.75	70.0	4.92e-01	100.0%	36.7%
3515339	3937.1.1.2 ↗	alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin	0.74	69.0	4.33e-01	100.0%	21.4%
3211467	3937.1.1.2 ↗	alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin	0.74	69.0	4.35e-01	100.0%	22.5%
3214243	3937.1.1.2 ↗	alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin	0.73	68.0	4.38e-01	100.0%	23.5%
3583608	3937.1.1.2 ↗	alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin	0.73	68.0	4.89e-01	100.0%	38.7%
3212571	3937.1.1.2 ↗	alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin	0.73	68.0	4.28e-01	100.0%	22.2%
3578921	3937.1.1.2 ↗	alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin	0.73	68.0	4.32e-01	100.0%	23.7%
3518544	5069.1.3.80 ↗	alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › Innexin	0.71	65.0	5.08e-01	100.0%	50.0%
3994619	3937.1.1.2 ↗	alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin	0.70	65.0	4.15e-01	100.0%	23.7%
3876440	3937.1.1.2 ↗	alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin	0.69	61.0	3.89e-01	100.0%	21.3%
4836806	1063.1.1.1 ↗	alpha complex topology › Tegument protein U14 › Tegument protein U14 › Tegument protein U14 › Herpes_pp85	0.52	46.0	3.02e-01	100.0%	41.2%

D2 medium residues 112-199_255-342

PDB

Domain cluster: rep: viral_innexin-b10.1__YP_001031255__Ichnoviriform_fugitivi__265522__D133-179_273-358

Pfam (2)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00876.24 best	Innexin	74.8	1.00e-20	51.1%	27.6%
PF00876.24	Innexin	55.3	8.60e-15	48.9%	24.3%

D3 medium residues 200-254

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00876.24 best	Innexin	28.5	1.30e-06	100.0%	14.1%

CATH (17)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4gs5A02	3.30.300.30	Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain	0.60	34.0	2.73e-01	100.0%	28.6%
5w8mA00	3.60.21.10	Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › Metallo-dependent phosphatases	0.60	42.0	2.88e-01	72.7%	59.2%
7f79A01	3.40.50.10860	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Leucine Dehydrogenase, chain A, domain 1	0.56	38.0	2.83e-01	72.7%	25.3%
3r0aA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.56	43.0	3.57e-01	94.5%	83.3%
3zqmA00	6.10.140.2160	Special › Helix non-globular › Helix Hairpins ›	0.54	42.0	4.21e-01	96.4%	86.4%
3klqA01	2.60.40.3050	Mainly Beta › Sandwich › Immunoglobulin-like ›	0.54	36.0	2.92e-01	81.8%	31.9%
1ilvA00	3.40.1210.10	Alpha Beta › 3-Layer(aba) Sandwich › Stationary-phase Survival Protein Sure Homolog; Chain: A, › Survival protein SurE-like phosphatase/nucleotidase	0.54	35.0	2.37e-01	87.3%	15.5%
7r5mA01	3.30.559.10	Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain	0.53	35.0	2.41e-01	70.9%	22.9%
1p1hB01	3.30.2360.10	Alpha Beta › 2-Layer Sandwich › Glyceraldehyde-3-phosphate dehydrogenase-like fold › Glyceraldehyde-3-phosphate dehydrogenase-like domain	0.53	45.0	3.21e-01	100.0%	60.8%
4jdeA01	2.60.40.3820	Mainly Beta › Sandwich › Immunoglobulin-like ›	0.53	42.0	3.31e-01	96.4%	82.5%
1vhzA01	3.90.79.10	Alpha Beta › Alpha-Beta Complex › Nucleoside Triphosphate Pyrophosphohydrolase › Nucleoside Triphosphate Pyrophosphohydrolase	0.52	39.0	2.86e-01	85.5%	42.7%
1pu1A00	3.30.300.100	Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › MTH677-like	0.52	43.0	3.80e-01	100.0%	92.3%
1xttB00	3.40.50.2020	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.51	41.0	2.95e-01	100.0%	82.7%
2ex5A00	3.10.28.10	Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases	0.51	37.0	2.60e-01	85.5%	21.3%
1bd3A00	3.40.50.2020	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.51	41.0	2.89e-01	100.0%	66.5%
5ekaA00	4.10.520.10	Few Secondary Structures › Irregular › HU Protein; Chain A › IHF-like DNA-binding proteins	0.51	35.0	3.13e-01	74.5%	72.9%
3j7aZ00	3.30.1230.20	Alpha Beta › 2-Layer Sandwich › Hypothetical Cytosolic Protein; Chain: A; › Ribosomal protein S21	0.50	33.0	3.13e-01	74.5%	51.4%

ECOD (39)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3389084	3937.1.1.2 ↗	alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin	0.90	83.0	4.99e-01	100.0%	17.9%
3225873	3937.1.1.2 ↗	alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin	0.86	69.0	4.05e-01	100.0%	12.7%
3391149	3937.1.1.2 ↗	alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin	0.83	77.0	4.56e-01	100.0%	16.3%
3414363	3937.1.1.2 ↗	alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin	0.82	75.0	4.43e-01	100.0%	15.9%
3472642	3937.1.1.2 ↗	alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin	0.79	72.0	4.23e-01	100.0%	13.6%
3211111	3937.1.1.2 ↗	alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin	0.78	71.0	4.21e-01	100.0%	14.7%
3813686	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.71	48.0	3.09e-01	70.9%	15.1%
5025980	101.1.2.914 ↗	alpha arrays › HTH › HTH › winged helix domain › DUF6015	0.71	52.0	4.37e-01	78.2%	85.6%
4980535	101.1.2.914 ↗	alpha arrays › HTH › HTH › winged helix domain › DUF6015	0.66	52.0	4.35e-01	85.5%	85.3%
4234844	7527.1.1.1 ↗	a/b three-layered sandwiches › SurE-like/CoA-transferase family III (CaiB/BaiF) › SurE-like/CoA-transferase family III (CaiB/BaiF) › SurE-like/CoA-transferase family III (CaiB/BaiF) › SurE	0.64	40.0	2.60e-01	70.9%	13.9%
5080275	101.1.2.914 ↗	alpha arrays › HTH › HTH › winged helix domain › DUF6015	0.63	50.0	3.87e-01	85.5%	68.3%
3395022	394.1.1.1 ↗	few secondary structure elements › Invertebrate chitin-binding proteins › Invertebrate chitin-binding proteins › Invertebrate chitin-binding proteins › CBM_14	0.62	42.0	3.87e-01	70.9%	63.0%
3717300	206.1.1.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase	0.62	44.0	2.58e-01	76.4%	19.6%
5019432	101.1.2.30 ↗	alpha arrays › HTH › HTH › winged helix domain › TrmB	0.61	49.0	3.94e-01	98.2%	76.9%
3479321	5001.1.1.41 ↗	alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw	0.61	46.0	2.82e-01	85.5%	12.7%
4943515	7527.1.1.1 ↗	a/b three-layered sandwiches › SurE-like/CoA-transferase family III (CaiB/BaiF) › SurE-like/CoA-transferase family III (CaiB/BaiF) › SurE-like/CoA-transferase family III (CaiB/BaiF) › SurE	0.59	38.0	2.58e-01	83.6%	15.1%
3223233	375.1.1.179 ↗	few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › TFIIE_alpha	0.59	43.0	2.89e-01	78.2%	35.2%
4433789	2004.1.1.14 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › GTP_EFTU	0.59	42.0	2.74e-01	100.0%	15.4%
3677582	2498.1.1.0 ↗	mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain"	0.58	42.0	2.78e-01	81.8%	19.2%
3608304	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.57	39.0	3.16e-01	70.9%	81.8%
3194847	3343.1.1.2 ↗	alpha complex topology › gamma-tubulin complex protein 4 (GCP4) › gamma-tubulin complex protein 4 (GCP4) › gamma-tubulin complex protein 4 (GCP4) › GCP_C_terminal,GCP_N_terminal	0.57	43.0	2.49e-01	87.3%	27.0%
3330279	2498.1.1.0 ↗	mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain"	0.56	38.0	2.54e-01	72.7%	17.6%
5056444	2002.1.1.29 ↗	a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › DHDPS	0.55	46.0	2.91e-01	100.0%	30.7%
4160692	171.1.1.1 ↗	alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonuclease_3	0.55	48.0	3.18e-01	98.2%	82.7%
None	—		0.54	40.0	2.85e-01	78.2%	43.8%
4399128	7581.1.1.30 ↗	a/b three-layered sandwiches › Thiolase-like › Thiolase-like › Thiolase-like › Thiolase_N, ketoacyl-synt, Thiolase_C	0.54	45.0	2.76e-01	98.2%	91.1%
3639498	101.1.2.722 ↗	alpha arrays › HTH › HTH › winged helix domain › DUF6581, PF28722	0.53	37.0	2.21e-01	72.7%	21.7%
4978825	101.1.2.30 ↗	alpha arrays › HTH › HTH › winged helix domain › TrmB	0.53	42.0	3.50e-01	100.0%	83.3%
3916165	633.23.1.22 ↗	alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL	0.53	46.0	3.25e-01	100.0%	85.1%
4233683	171.1.1.1 ↗	alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonuclease_3	0.53	45.0	3.05e-01	100.0%	58.2%
4032453	101.1.9.78 ↗	alpha arrays › HTH › HTH › Putative DNA-binding domain › AntA	0.52	37.0	3.18e-01	78.2%	93.7%
3224634	5001.1.1.41 ↗	alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw	0.52	40.0	2.55e-01	96.4%	37.3%
3181301	101.1.2.569 ↗	alpha arrays › HTH › HTH › winged helix domain › PF28722	0.51	39.0	2.95e-01	85.5%	89.7%
3394822	375.1.1.179 ↗	few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › TFIIE_alpha	0.51	38.0	2.71e-01	83.6%	41.5%
3485716	101.1.2.31 ↗	alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha	0.51	40.0	2.98e-01	100.0%	90.5%
4595166	5076.2.1.0 ↗	alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ	0.51	39.0	2.64e-01	87.3%	22.2%
5010647	1075.1.1.0 ↗	alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain	0.50	42.0	2.89e-01	100.0%	28.4%
3517620	5001.1.1.1 ↗	alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1	0.50	40.0	2.54e-01	89.1%	16.9%
3488429	375.1.1.179 ↗	few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › TFIIE_alpha	0.50	39.0	2.94e-01	100.0%	92.4%