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virion_protein_US2

Euk-Vir

Equid_alphaherpesvirus_9

virion_protein_US2__YP_002333549__Equid_alphaherpesvirus_9__55744

Identity

Accession:
YP_002333549 ↗
Protein ID:
virion_protein_US2
Kingdom:
euk

Quality

67.9 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Varicellovirus› Equid_alphaherpesvirus_9

TaxID: 55744

Cluster

Singleton — not in a non-trivial cluster

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 3-179_203-222
PDB
Domain cluster: rep: dihydrofolate_reductase__YP_009119754__Pandoravirus_inopinatum__1605721__D21-210
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02476.22 best US2 183.6 4.00e-54 97.0% 89.0%
CATH (79)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1dhiA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.75 58.0 6.45e-01 99.0% 100.0%
3vcoA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.74 65.0 6.80e-01 99.5% 99.5%
2w9hA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.74 57.0 6.32e-01 99.0% 100.0%
5eccA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.73 57.0 6.25e-01 100.0% 100.0%
6pf8A01 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.72 62.0 6.50e-01 100.0% 100.0%
3ix9A00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.72 58.0 6.30e-01 100.0% 99.4%
1ao8A00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.72 56.0 6.15e-01 98.5% 99.4%
1vdrA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.72 55.0 6.12e-01 99.0% 100.0%
1bozA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.71 64.0 6.56e-01 100.0% 100.0%
3k2hA01 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.71 62.0 6.35e-01 100.0% 96.8%
1cz3B00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.70 56.0 6.08e-01 99.5% 98.2%
2xw7A00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.69 57.0 6.07e-01 100.0% 98.3%
3nzbX00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.68 63.0 6.26e-01 100.0% 98.5%
3eoeD01 3.40.1380.20 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate Kinase; Chain: A, domain 1 › Pyruvate kinase, C-terminal domain 0.67 35.0 4.22e-01 86.3% 73.0%
3jtwA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.67 57.0 5.98e-01 100.0% 100.0%
2p4gA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.67 63.0 5.76e-01 100.0% 92.7%
1aoeA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.66 59.0 6.05e-01 100.0% 99.0%
1j3jB00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.66 61.0 5.96e-01 100.0% 95.8%
2gd9A01 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.65 53.0 5.71e-01 98.0% 100.0%
3zpgA02 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.64 59.0 5.77e-01 100.0% 95.4%
2b3zA02 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.64 59.0 5.64e-01 99.5% 95.6%
2aznA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.64 59.0 5.73e-01 100.0% 99.1%
1juvA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.62 57.0 5.76e-01 98.5% 100.0%
2hxvA02 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.62 58.0 5.83e-01 100.0% 100.0%
1ri5A00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.62 51.0 4.72e-01 87.8% 98.4%
2g6vA02 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.61 57.0 5.49e-01 100.0% 95.5%
3kgyA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.61 56.0 5.46e-01 100.0% 97.2%
1mjfB02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.60 49.0 4.79e-01 85.8% 94.9%
7uehA01 3.40.1380.20 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate Kinase; Chain: A, domain 1 › Pyruvate kinase, C-terminal domain 0.60 36.0 4.53e-01 85.3% 98.3%
4ha7B00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.60 53.0 5.25e-01 100.0% 89.8%
1e3jA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.60 40.0 4.71e-01 85.8% 97.1%
1e0tA01 3.40.1380.20 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate Kinase; Chain: A, domain 1 › Pyruvate kinase, C-terminal domain 0.60 35.0 4.36e-01 85.3% 92.7%
3e0vB01 3.40.1380.20 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate Kinase; Chain: A, domain 1 › Pyruvate kinase, C-terminal domain 0.59 36.0 3.99e-01 86.8% 73.3%
4lg1B00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.59 50.0 4.90e-01 89.8% 86.4%
4hg2B01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.59 47.0 5.01e-01 87.8% 97.0%
1ej6A04 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.59 49.0 4.67e-01 87.8% 95.2%
3ndiA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.59 50.0 5.05e-01 91.4% 96.0%
3a7eA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.59 49.0 4.84e-01 88.8% 83.5%
2p7iA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.59 48.0 4.66e-01 87.8% 100.0%
3htxD03 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.58 48.0 4.64e-01 86.8% 91.0%
4xcxA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.58 48.0 4.66e-01 87.3% 89.4%
3dliA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.58 49.0 4.71e-01 89.8% 96.8%
4htfA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.58 47.0 4.45e-01 87.8% 93.9%
3busB00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.57 48.0 4.52e-01 89.3% 99.6%
1nv8A02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.57 48.0 4.90e-01 89.8% 91.9%
2yqzA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.57 48.0 4.89e-01 89.8% 94.3%
7wm5A01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.57 46.0 4.57e-01 89.8% 81.2%
1xcjA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.57 48.0 4.62e-01 90.9% 95.6%
3v97A02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.57 45.0 4.85e-01 88.3% 98.8%
4pneA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.57 49.0 4.43e-01 93.4% 98.5%
3tmaA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.56 45.0 4.75e-01 87.8% 94.4%
3egiA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.56 45.0 4.59e-01 86.8% 85.6%
3egeA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.56 47.0 4.36e-01 88.8% 99.2%
7bfpA01 3.40.50.10890 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.56 40.0 4.52e-01 86.3% 98.6%
2fpoC00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.56 44.0 4.56e-01 88.8% 89.5%
4yhbA02 3.40.50.80 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module 0.55 36.0 4.22e-01 98.0% 95.5%
1suiA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.55 48.0 4.65e-01 94.9% 98.2%
3eodA00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.55 32.0 4.10e-01 80.2% 98.3%
4qdjA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.55 46.0 4.60e-01 90.9% 94.7%
3s28A03 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.55 51.0 4.38e-01 100.0% 88.8%
5fcdA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.55 46.0 4.39e-01 89.8% 100.0%
1jg1A00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.54 40.0 3.94e-01 87.3% 69.8%
3frhA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.54 42.0 4.33e-01 89.8% 87.4%
6ejiA01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.53 47.0 4.83e-01 98.5% 98.9%
3futA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.53 46.0 4.58e-01 91.4% 91.0%
3plnA03 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.53 36.0 4.06e-01 75.1% 88.3%
1y7lA02 3.40.50.1100 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.53 30.0 3.83e-01 82.7% 100.0%
2jjqA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.53 44.0 4.50e-01 93.4% 90.7%
2yn0A00 3.40.50.1240 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphoglycerate mutase-like 0.53 47.0 4.39e-01 97.0% 97.2%
2qyoA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.53 44.0 4.10e-01 89.8% 79.9%
1wznA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.53 44.0 4.55e-01 90.4% 96.3%
3eozB01 3.40.50.1240 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphoglycerate mutase-like 0.52 38.0 4.15e-01 75.1% 100.0%
2b78A03 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.52 44.0 4.32e-01 89.8% 90.9%
3ezsA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.52 44.0 4.15e-01 90.4% 85.1%
1bs0A02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.52 44.0 4.23e-01 90.9% 81.1%
2igtA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.51 45.0 4.20e-01 94.4% 91.9%
4hwgA01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.51 47.0 4.57e-01 100.0% 98.1%
1wyuB03 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.51 43.0 3.90e-01 90.9% 80.6%
3h1tA03 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 45.0 4.47e-01 97.0% 94.7%
ECOD (88)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4276639 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.75 60.0 6.42e-01 100.0% 96.5%
2503171 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.72 61.0 6.44e-01 100.0% 98.3%
4402042 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.72 64.0 6.59e-01 99.5% 100.0%
3900511 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.71 63.0 6.49e-01 100.0% 99.5%
185430 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.71 61.0 6.33e-01 100.0% 96.8%
3913441 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.71 64.0 6.54e-01 100.0% 98.9%
3232633 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.69 62.0 6.37e-01 99.5% 100.0%
4667474 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.69 60.0 6.25e-01 98.5% 100.0%
4228699 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.68 63.0 6.29e-01 98.5% 100.0%
4183099 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.68 57.0 5.95e-01 100.0% 96.1%
4392834 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.68 64.0 6.05e-01 100.0% 98.3%
5058063 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.68 57.0 6.07e-01 100.0% 100.0%
10268 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.68 63.0 6.28e-01 100.0% 98.5%
136031 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.67 63.0 6.15e-01 100.0% 100.0%
3056343 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.67 63.0 6.18e-01 100.0% 94.3%
3187913 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.67 62.0 6.05e-01 100.0% 99.5%
136641 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.67 57.0 5.98e-01 100.0% 100.0%
4115051 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.66 62.0 5.77e-01 100.0% 96.7%
5063695 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.66 59.0 6.05e-01 99.5% 98.4%
3278932 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.65 59.0 6.04e-01 100.0% 100.0%
3279668 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.65 57.0 5.94e-01 99.5% 100.0%
4577003 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.64 60.0 5.82e-01 100.0% 98.6%
5001085 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.64 60.0 5.62e-01 100.0% 92.8%
5009586 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.64 59.0 5.78e-01 99.0% 98.6%
235716 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.64 59.0 5.86e-01 100.0% 100.0%
3286316 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.64 56.0 5.75e-01 100.0% 99.5%
4954734 7518.1.1.1 ↗ a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › PK_C 0.63 38.0 4.75e-01 86.3% 95.8%
4946280 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.63 58.0 5.60e-01 99.5% 99.5%
4173461 2003.1.5.79 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_23 0.61 52.0 4.53e-01 89.3% 89.0%
3963509 7518.1.1.1 ↗ a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › PK_C 0.60 36.0 4.40e-01 85.8% 90.8%
4942915 2003.1.5.19 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › TRM 0.60 50.0 4.16e-01 88.8% 83.8%
4947473 2003.4.1.1 ↗ a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP 0.60 37.0 4.17e-01 85.3% 80.0%
4981190 7518.1.1.1 ↗ a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › PK_C 0.59 36.0 4.42e-01 86.8% 94.4%
4516103 7518.1.1.1 ↗ a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › PK_C 0.59 36.0 4.44e-01 85.8% 95.9%
4995793 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.59 46.0 5.02e-01 94.9% 100.0%
None — 0.59 50.0 4.30e-01 92.9% 90.8%
3757398 2003.1.5.97 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_32 0.59 51.0 4.10e-01 93.4% 90.9%
3630392 7518.1.1.1 ↗ a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › PK_C 0.59 36.0 4.37e-01 86.8% 91.7%
3849065 2003.1.5.97 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_32 0.59 51.0 4.23e-01 93.4% 91.3%
4975093 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.58 51.0 4.56e-01 93.4% 97.1%
4932130 7518.1.1.1 ↗ a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › PK_C 0.58 36.0 4.30e-01 86.8% 90.8%
5075261 2003.1.5.81 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.58 51.0 4.54e-01 93.4% 93.8%
5038356 2003.1.5.69 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › GCD14 0.58 44.0 4.79e-01 88.8% 94.5%
4947582 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.58 50.0 4.43e-01 92.4% 90.2%
3958114 2003.4.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes 0.58 37.0 4.14e-01 85.8% 82.0%
165681 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.58 49.0 4.47e-01 90.4% 96.6%
4677963 2003.1.5.2 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › RrnaAD 0.58 49.0 4.83e-01 91.4% 92.1%
3500538 7518.1.1.1 ↗ a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › PK_C 0.58 36.0 4.32e-01 86.3% 89.9%
5032810 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.58 48.0 4.44e-01 89.3% 94.2%
2553360 7518.1.1.1 ↗ a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › PK_C 0.58 36.0 4.31e-01 86.8% 90.5%
3683296 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.57 49.0 4.05e-01 92.9% 79.7%
3952836 2003.1.5.81 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.57 49.0 4.37e-01 93.4% 88.3%
3394634 2003.1.5.97 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_32 0.57 50.0 4.43e-01 93.4% 91.8%
5045564 2003.1.5.8 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Ubie_methyltran 0.57 48.0 4.65e-01 90.4% 96.0%
3180686 2003.1.5.152 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › CMAS, Methyltransf_25 0.57 48.0 4.09e-01 90.9% 84.0%
4988583 2003.1.5.209 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PF29244 0.57 43.0 4.72e-01 90.9% 99.4%
4998635 7518.1.1.1 ↗ a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › PK_C 0.57 36.0 4.41e-01 87.8% 96.9%
3717817 2003.1.5.11 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PARP_regulatory 0.57 47.0 4.10e-01 88.8% 68.5%
9395 2003.1.5.151 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_23, Methyltransf_25 0.56 48.0 4.47e-01 91.4% 98.0%
4977257 2003.1.5.82 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_31 0.56 47.0 4.38e-01 90.4% 98.4%
5037445 2003.1.5.81 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.56 48.0 4.37e-01 91.4% 99.2%
3275654 2003.1.5.97 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_32 0.56 49.0 4.10e-01 93.9% 87.2%
4429287 2003.1.5.15 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › FtsJ 0.56 47.0 4.69e-01 90.4% 97.6%
4004032 2003.1.5.82 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_31 0.56 44.0 4.68e-01 89.3% 94.3%
3404546 7518.1.1.1 ↗ a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › PK_C 0.56 39.0 4.41e-01 88.3% 92.7%
4955361 2003.1.5.81 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.56 46.0 4.28e-01 89.3% 94.5%
4974362 2003.1.5.81 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.56 47.0 4.36e-01 90.4% 98.4%
3989865 2003.1.5.81 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.56 47.0 4.42e-01 90.9% 99.2%
3386250 2003.1.5.46 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › MTS 0.56 47.0 4.70e-01 89.8% 91.5%
5057874 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.55 47.0 4.70e-01 91.4% 94.1%
4931549 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.55 48.0 4.29e-01 92.9% 93.5%
4408393 2003.1.5.174 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › tRNA_U5-meth_tr, Methyltransf_15 0.55 48.0 3.91e-01 94.4% 94.9%
3800974 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.55 46.0 4.22e-01 90.4% 90.2%
None — 0.55 48.0 4.60e-01 94.4% 96.4%
4003781 2003.1.5.5 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › UPF0020 0.54 45.0 4.20e-01 88.3% 94.3%
4982424 2003.1.5.81 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.54 46.0 4.31e-01 91.4% 98.4%
3510809 2003.1.5.13 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Spermine_synth 0.54 47.0 4.72e-01 91.9% 93.3%
5059212 2003.1.5.69 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › GCD14 0.54 45.0 4.58e-01 89.3% 94.7%
4224328 2003.1.5.107 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › AdoMet_MTase 0.53 45.0 4.26e-01 89.8% 85.1%
3502395 2003.1.5.5 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › UPF0020 0.53 45.0 4.03e-01 90.4% 90.4%
3937503 7573.1.1.4 ↗ a/b three-layered sandwiches › PRTase-like › PRTase-like › PRTase-like › UPRTase 0.53 41.0 4.17e-01 79.7% 90.5%
5010978 7577.1.1.4 ↗ a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › Pyridoxal_deC 0.53 45.0 3.68e-01 91.4% 60.6%
None — 0.52 46.0 3.79e-01 94.4% 97.2%
4936070 2003.1.5.5 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › UPF0020 0.52 43.0 4.46e-01 89.8% 92.6%
3204920 2003.1.5.15 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › FtsJ 0.52 44.0 3.79e-01 90.9% 72.9%
1102197 101.1.2.163 ↗ alpha arrays › HTH › HTH › winged helix domain › PMT2_N 0.51 41.0 4.37e-01 87.8% 97.1%
4989148 7518.1.1.1 ↗ a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › PK_C 0.51 31.0 3.68e-01 100.0% 88.1%
3631357 7577.1.1.4 ↗ a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › Pyridoxal_deC 0.50 44.0 3.54e-01 94.9% 88.6%