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virion_transactivator

Euk-Vir

Human_betaherpesvirus_6B

virion_transactivator__NP_050235__Human_betaherpesvirus_6B__32604

Identity

Accession:
NP_050235 ↗
Protein ID:
virion_transactivator
Kingdom:
euk

Quality

85.2 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Roseolovirus› Human_betaherpesvirus_6B

TaxID: 32604

Cluster

View cluster (23 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 8-98_380-446
PDB
Domain cluster: rep: E84__YP_007016481__Murid_betaherpesvirus_8__1261657__D3-113_445-495
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05784.17 best Herpes_UL82_83 112.1 3.80e-32 64.6% 31.0%
D2 high residues 103-237
PDB
Domain cluster: rep: protein_UL84__YP_004940247__Saimiriine_betaherpesvirus_4__1535247__D144-278
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05784.17 best Herpes_UL82_83 131.4 5.20e-38 100.0% 38.8%
D3 high residues 251-270_284-336
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05784.17 best Herpes_UL82_83 66.8 2.30e-18 100.0% 15.9%
CATH (44)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2d4lA01 2.70.40.10 Mainly Beta › Distorted Sandwich › Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A › Deoxyuridine triphosphatase (dUTPase) 0.87 78.0 6.82e-01 97.3% 84.9%
2yzjA01 2.70.40.10 Mainly Beta › Distorted Sandwich › Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A › Deoxyuridine triphosphatase (dUTPase) 0.86 78.0 6.14e-01 97.3% 81.4%
1sixA00 2.70.40.10 Mainly Beta › Distorted Sandwich › Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A › Deoxyuridine triphosphatase (dUTPase) 0.84 77.0 5.96e-01 100.0% 62.7%
5y5qC00 2.70.40.10 Mainly Beta › Distorted Sandwich › Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A › Deoxyuridine triphosphatase (dUTPase) 0.81 73.0 5.87e-01 100.0% 67.9%
2r9qC01 2.70.40.10 Mainly Beta › Distorted Sandwich › Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A › Deoxyuridine triphosphatase (dUTPase) 0.81 73.0 5.56e-01 100.0% 79.1%
2bsyA01 2.70.40.10 Mainly Beta › Distorted Sandwich › Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A › Deoxyuridine triphosphatase (dUTPase) 0.79 71.0 5.63e-01 100.0% 60.5%
1tulA00 2.70.40.20 Mainly Beta › Distorted Sandwich › Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A › Baculovirus telokin-like protein 20 0.69 58.0 5.26e-01 95.9% 83.3%
6tqdC01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.67 56.0 5.17e-01 94.5% 85.4%
4b96A00 2.60.40.710 Mainly Beta › Sandwich › Immunoglobulin-like › Endoglucanase-like 0.67 56.0 4.46e-01 93.2% 62.3%
4zrxA02 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.64 54.0 4.80e-01 94.5% 99.0%
3esmA00 2.60.40.2230 Mainly Beta › Sandwich › Immunoglobulin-like › Uncharacterised protein YcnI-like PF07987, DUF1775 0.64 53.0 4.34e-01 93.2% 56.5%
2oznA00 2.60.40.680 Mainly Beta › Sandwich › Immunoglobulin-like › 0.63 53.0 4.43e-01 95.9% 58.6%
3nngA00 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.61 51.0 4.12e-01 95.9% 96.1%
4mbrA01 2.60.40.1280 Mainly Beta › Sandwich › Immunoglobulin-like › 0.60 51.0 4.15e-01 98.6% 58.7%
4iefA00 2.60.40.3800 Mainly Beta › Sandwich › Immunoglobulin-like › 0.60 51.0 3.89e-01 100.0% 81.2%
4v15A01 2.40.37.20 Mainly Beta › Beta Barrel › Lyase, Ornithine Decarboxylase; Chain A, domain 1 › D-serine dehydratase-like domain 0.58 50.0 4.09e-01 98.6% 89.6%
2awnC03 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.58 35.0 3.84e-01 84.9% 75.9%
3uesA02 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.57 45.0 3.98e-01 91.8% 100.0%
1opoA02 2.60.40.1780 Mainly Beta › Sandwich › Immunoglobulin-like › Carmovirus coat protein 0.57 46.0 4.21e-01 93.2% 98.1%
3eypA02 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.56 44.0 3.77e-01 90.4% 100.0%
4aw7A03 2.60.120.1200 Mainly Beta › Sandwich › Jelly Rolls › 0.56 44.0 3.92e-01 94.5% 71.3%
4frwA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.56 44.0 4.17e-01 93.2% 81.2%
1dv2A02 3.30.470.20 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain 0.55 41.0 2.90e-01 84.9% 61.2%
8ediA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.55 44.0 4.02e-01 93.2% 84.6%
1o0vA03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.55 44.0 3.95e-01 93.2% 80.0%
4o5lL02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.55 44.0 4.05e-01 94.5% 84.6%
5h80B03 3.30.470.20 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain 0.55 42.0 2.96e-01 84.9% 68.9%
4ofdB02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.55 43.0 4.08e-01 93.2% 86.3%
1cqkA00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 43.0 4.01e-01 93.2% 85.1%
4q9bA00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 43.0 4.03e-01 94.5% 87.1%
2c5dC01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 44.0 3.98e-01 94.5% 84.6%
2e9wA04 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 43.0 3.94e-01 93.2% 83.3%
6x4tA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 40.0 3.85e-01 84.9% 89.4%
1kcvL02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 41.0 3.84e-01 93.2% 88.3%
3o4oC03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 43.0 3.88e-01 95.9% 88.2%
4kbxA01 2.40.37.30 Mainly Beta › Beta Barrel › Lyase, Ornithine Decarboxylase; Chain A, domain 1 › 0.53 40.0 2.92e-01 84.9% 78.2%
7k0xA03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.52 43.0 4.24e-01 94.5% 91.0%
4rz0A00 2.170.270.10 Mainly Beta › Beta Complex › Beta-clip-like › SET domain 0.52 38.0 3.32e-01 78.1% 91.2%
5wl1A02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.51 40.0 3.75e-01 93.2% 83.2%
1v0fB03 2.40.30.20 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › 0.51 42.0 4.08e-01 100.0% 97.6%
1c16A02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.51 40.0 3.79e-01 93.2% 83.5%
1xakA00 2.60.40.1550 Mainly Beta › Sandwich › Immunoglobulin-like › SARS coronavirus X4 0.51 36.0 3.66e-01 91.8% 80.9%
1es0A02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.51 41.0 3.81e-01 94.5% 83.8%
3pv7A02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.50 40.0 3.75e-01 91.8% 88.3%
ECOD (31)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
367299 70.2.1.0 ↗ beta barrels › beta-clip › dUTPase-like › dUTPase-like 0.77 69.0 6.02e-01 100.0% 79.5%
3242079 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.69 59.0 5.27e-01 95.9% 77.1%
759 70.2.1.2 ↗ beta barrels › beta-clip › dUTPase-like › dUTPase-like › TLP-20 0.69 58.0 5.26e-01 95.9% 83.3%
3479280 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.66 57.0 4.92e-01 98.6% 92.4%
3676554 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.64 55.0 4.59e-01 95.9% 68.8%
3282461 11.1.5.28 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f › DUF1775 0.64 53.0 4.15e-01 93.2% 48.8%
1557261 10.32.1.0 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like 0.63 51.0 4.57e-01 94.5% 96.4%
3905354 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.62 51.0 4.33e-01 93.2% 64.0%
4969606 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.61 48.0 4.32e-01 90.4% 82.7%
5070791 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.60 49.0 4.48e-01 93.2% 84.0%
3320100 10.32.1.0 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like 0.60 50.0 4.20e-01 100.0% 95.7%
3998175 11.1.5.114 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f › Integrin_A_Ig_2 0.59 50.0 4.36e-01 95.9% 69.6%
3869055 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.59 46.0 4.32e-01 86.3% 84.4%
3559589 11.1.1.591 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › NUP210_Ig7 0.58 45.0 3.98e-01 86.3% 74.5%
3182777 70.3.1.1 ↗ beta barrels › beta-clip › SET domain-like › SET domain-like › SET 0.57 45.0 3.04e-01 89.0% 77.7%
1125231 325.1.5.1 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Ribosomal protein L10e › Ribosomal_L16 0.56 38.0 3.11e-01 72.6% 66.2%
5071126 12.1.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain 0.55 47.0 4.71e-01 95.9% 94.7%
3027089 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.54 42.0 4.09e-01 91.8% 85.1%
3578304 11.1.1.297 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Integrin_A_Ig_2 0.54 44.0 3.71e-01 97.3% 56.4%
3739593 70.3.1.1 ↗ beta barrels › beta-clip › SET domain-like › SET domain-like › SET 0.52 37.0 2.62e-01 75.3% 89.4%
3310253 70.3.1.1 ↗ beta barrels › beta-clip › SET domain-like › SET domain-like › SET 0.51 38.0 2.81e-01 82.2% 64.5%
3854192 11.1.1.947 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › VEGFR-1-like_Ig-like, VEGFR1-3_N_Ig-like 0.51 40.0 3.16e-01 91.8% 42.2%
3684421 10.12.1.0 ↗ beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix 0.51 44.0 3.47e-01 100.0% 49.1%
3928465 70.3.1.13 ↗ beta barrels › beta-clip › SET domain-like › SET domain-like › SET_TTL 0.51 37.0 2.76e-01 79.5% 74.5%
153388 11.1.1.96 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › C1-set 0.51 39.0 3.71e-01 91.8% 85.7%
3925638 70.3.1.1 ↗ beta barrels › beta-clip › SET domain-like › SET domain-like › SET 0.51 37.0 2.81e-01 82.2% 57.7%
3493392 70.3.1.13 ↗ beta barrels › beta-clip › SET domain-like › SET domain-like › SET_TTL 0.51 41.0 2.87e-01 89.0% 62.1%
3229770 70.3.1.13 ↗ beta barrels › beta-clip › SET domain-like › SET domain-like › SET_TTL 0.51 36.0 2.76e-01 79.5% 71.9%
3641863 70.3.1.0 ↗ beta barrels › beta-clip › SET domain-like › SET domain-like 0.50 38.0 2.78e-01 86.3% 54.0%
3394051 12.2.1.4 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Hyaluronate lyase-like, C-terminal domain › Hyaluronate lyase-like, C-terminal domain › Vanin_C 0.50 40.0 3.13e-01 94.5% 56.3%
3396359 70.3.1.13 ↗ beta barrels › beta-clip › SET domain-like › SET domain-like › SET_TTL 0.50 37.0 2.71e-01 80.8% 74.8%